Zobrazeno 1 - 10
of 186
pro vyhledávání: '"Anne M Remes"'
Autor:
Helmi Soppela, Kasper Katisko, Yasmine Gadola, Johanna Krüger, Päivi Hartikainen, Antonella Alberici, Alberto Benussi, Anne Koivisto, Annakaisa Haapasalo, Anne M Remes, Barbara Borroni, Eino Solje
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 9, Iss 8, Pp 1195-1205 (2022)
Abstract Objective Only a few studies have evaluated modifiable risk factors for frontotemporal dementia (FTD). Here, we evaluated several modifiable factors and their association with disease phenotype, genotype, and prognosis in a large study popul
Externí odkaz:
https://doaj.org/article/334b55288d004b98bb80d40b5c93e92f
Autor:
Hanneke F M Rhodius-Meester, Ingrid S van Maurik, Juha Koikkalainen, Antti Tolonen, Kristian S Frederiksen, Steen G Hasselbalch, Hilkka Soininen, Sanna-Kaisa Herukka, Anne M Remes, Charlotte E Teunissen, Frederik Barkhof, Yolande A L Pijnenburg, Philip Scheltens, Jyrki Lötjönen, Wiesje M van der Flier
Publikováno v:
PLoS ONE, Vol 15, Iss 1, p e0226784 (2020)
INTRODUCTION:An accurate and timely diagnosis for Alzheimer's disease (AD) is important, both for care and research. The current diagnostic criteria allow the use of CSF biomarkers to provide pathophysiological support for the diagnosis of AD. How th
Externí odkaz:
https://doaj.org/article/d230e97885c542eebef34abcaed775eb
Autor:
Tong Tong, Christian Ledig, Ricardo Guerrero, Andreas Schuh, Juha Koikkalainen, Antti Tolonen, Hanneke Rhodius, Frederik Barkhof, Betty Tijms, Afina W Lemstra, Hilkka Soininen, Anne M Remes, Gunhild Waldemar, Steen Hasselbalch, Patrizia Mecocci, Marta Baroni, Jyrki Lötjönen, Wiesje van der Flier, Daniel Rueckert
Publikováno v:
NeuroImage: Clinical, Vol 15, Iss , Pp 613-624 (2017)
Differentiating between different types of neurodegenerative diseases is not only crucial in clinical practice when treatment decisions have to be made, but also has a significant potential for the enrichment of clinical trials. The purpose of this s
Externí odkaz:
https://doaj.org/article/b4f1eb19393d42ecaf67314d22594742
Autor:
Eino Solje, Heidi Aaltokallio, Heli Koivumaa-Honkanen, Noora M Suhonen, Virpi Moilanen, Anna Kiviharju, Bryan Traynor, Pentti J Tienari, Päivi Hartikainen, Anne M Remes
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0131817 (2015)
The C9ORF72 expansion is one of the most common genetic etiologies observed with behavioural variant frontotemporal dementia (bvFTD). Revised diagnostic criteria for bvFTD (FTDC) were recently introduced but only a few studies have evaluated the accu
Externí odkaz:
https://doaj.org/article/df03e3f571a641ac93b3fa651e6e1eea
Autor:
Lyzel S Elias-Sonnenschein, Seppo Helisalmi, Teemu Natunen, Anette Hall, Teemu Paajanen, Sanna-Kaisa Herukka, Marjo Laitinen, Anne M Remes, Anne M Koivisto, Kari M Mattila, Terho Lehtimäki, Frans R J Verhey, Pieter Jelle Visser, Hilkka Soininen, Mikko Hiltunen
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e59676 (2013)
OBJECTIVES: To understand the relation between risk genes for Alzheimer's disease (AD) and their influence on biomarkers for AD, we examined the association of AD in the Finnish cohort with single nucleotide polymorphisms (SNPs) from top AlzGene loci
Externí odkaz:
https://doaj.org/article/c9f56374400345e98bb710f9782bb034
Autor:
Marie Bruun, Kristian S. Frederiksen, Hanneke F. M. Rhodius-Meester, Marta Baroni, Le Gjerum, Juha Koikkalainen, Timo Urhemaa, Antti Tolonen, Mark van Gils, Daniel Rueckert, Nadia Dyremose, Birgitte B. Andersen, Afina W. Lemstra, Merja Hallikainen, Sudhir Kurl, Sanna-Kaisa Herukka, Anne M. Remes, Gunhild Waldemar, Hilkka Soininen, Patrizia Mecocci, Wiesje M. van der Flier, Jyrki Lötjönen, Steen G. Hasselbalch
Publikováno v:
Alzheimer’s Research & Therapy, Vol 11, Iss 1, Pp 1-11 (2019)
Abstract Background In clinical practice, it is often difficult to predict which patients with cognitive complaints or impairment will progress or remain stable. We assessed the impact of using a clinical decision support system, the PredictND tool,
Externí odkaz:
https://doaj.org/article/e6d0259039dc46d6a5e8c049faf11b34
Autor:
Sami Heikkinen, Nadine Huber, Kasper Katisko, Tarja Kokkola, Päivi Hartikainen, Johanna Krüger, Ville Leinonen, Ville E. Korhonen, Sanna-Kaisa Herukka, Anne M. Remes, Barbara Borroni, Antonella Alberici, Ilenia Libri, Eino Solje, Annakaisa Haapasalo
Publikováno v:
Journal of Alzheimer's Disease. 93:395-401
Frontotemporal dementia (FTD) can manifest as diverse clinical phenotypes and is frequently caused by mutations in different genes, complicating differential diagnosis. This underlines the urgent need for valid biomarkers. Altered lysosomal and immun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ff0fd1610a1fd1dc0a0bb6d9e2985b8
https://doi.org/10.3233/jad-221060
https://doi.org/10.3233/jad-221060
Autor:
Helmi Soppela, Johanna Krüger, Päivi Hartikainen, Anne Koivisto, Annakaisa Haapasalo, Barbara Borroni, Anne M. Remes, Kasper Katisko, Eino Solje
Publikováno v:
Journal of Alzheimer's Disease. 91:225-232
Background: Currently, there are few studies considering possible modifiable risk factors of frontotemporal dementia (FTD). Objective: In this retrospective case-control study, we evaluated whether a history of traumatic brain injury (TBI) associates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2f0e716b824d9afcb74ce01ee6bb559
https://doi.org/10.3233/jad-220545
https://doi.org/10.3233/jad-220545
Autor:
Samuli Huttula, Henri Väyrynen, Seppo Helisalmi, Laura Kytövuori, Laura Luukkainen, Mikko Hiltunen, Anne M Remes, Johanna Krüger
Publikováno v:
Neurobiology of Aging. 114:113-116
Early-onset dementia (EOD) is highly heritable. However, in many EOD cases the genetic etiology remains unknown. Mitochondrial dysfunction is associated with neurodegeneration and the complex I (CI) deficiency is the most common enzyme deficiency in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9546128dfe748c927db9aba7bebf5f10
https://doi.org/10.1016/j.neurobiolaging.2021.09.026
https://doi.org/10.1016/j.neurobiolaging.2021.09.026
Autor:
Hannah Rostalski, Stina Leskelä, Nadine Huber, Kasper Katisko, Antti Cajanus, Eino Solje, Mikael Marttinen, Teemu Natunen, Anne M. Remes, Mikko Hiltunen, Annakaisa Haapasalo
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
Frontotemporal lobar degeneration (FTLD) and amyotrophic lateral sclerosis (ALS) are neurodegenerative diseases with a complex, but often overlapping, genetic and pathobiological background and thus they are considered to form a disease spectrum. Alt
Externí odkaz:
https://doaj.org/article/e1d3a20842544134bab22774b056de7e