Zobrazeno 1 - 10
of 326
pro vyhledávání: '"Anne M Remes"'
Autor:
Kasper Katisko, Nadine Huber, Tarja Kokkola, Päivi Hartikainen, Johanna Krüger, Anna-Leena Heikkinen, Veera Paananen, Ville Leinonen, Ville E. Korhonen, Seppo Helisalmi, Sanna-Kaisa Herukka, Valentina Cantoni, Yasmine Gadola, Silvana Archetti, Anne M. Remes, Annakaisa Haapasalo, Barbara Borroni, Eino Solje
Publikováno v:
Alzheimer’s Research & Therapy, Vol 14, Iss 1, Pp 1-10 (2022)
Abstract Background Frontotemporal dementia (FTD) covers a spectrum of neurodegenerative disorders with various clinical and neuropathological subtypes. The two major pathological proteins accumulating in the brains of FTD patients, depending on thei
Externí odkaz:
https://doaj.org/article/3f83909ddbda4779af3f6dea81f281ff
Autor:
Helmi Soppela, Kasper Katisko, Yasmine Gadola, Johanna Krüger, Päivi Hartikainen, Antonella Alberici, Alberto Benussi, Anne Koivisto, Annakaisa Haapasalo, Anne M Remes, Barbara Borroni, Eino Solje
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 9, Iss 8, Pp 1195-1205 (2022)
Abstract Objective Only a few studies have evaluated modifiable risk factors for frontotemporal dementia (FTD). Here, we evaluated several modifiable factors and their association with disease phenotype, genotype, and prognosis in a large study popul
Externí odkaz:
https://doaj.org/article/334b55288d004b98bb80d40b5c93e92f
Autor:
Heikki Lukkarinen, Anna Jeppsson, Carsten Wikkelsö, Kaj Blennow, Henrik Zetterberg, Radu Constantinescu, Anne M. Remes, Sanna-Kaisa Herukka, Mikko Hiltunen, Tuomas Rauramaa, Katarina Nägga, Ville Leinonen, Mats Tullberg
Publikováno v:
Fluids and Barriers of the CNS, Vol 19, Iss 1, Pp 1-13 (2022)
Abstract Background The relationship between cerebrospinal fluid (CSF) biomarkers and the clinical features of idiopathic normal pressure hydrocephalus (iNPH) has been inconclusive. We aimed to evaluate CSF biomarkers reflecting Alzheimer’s disease
Externí odkaz:
https://doaj.org/article/e3306e30d43144a4816b527fa1a87edd
Autor:
Marja Niiranen, Juha Koikkalainen, Jyrki Lötjönen, Tuomas Selander, Antti Cajanus, Päivi Hartikainen, Sakari Simula, Ritva Vanninen, Anne M. Remes
Publikováno v:
Brain and Behavior, Vol 12, Iss 7, Pp n/a-n/a (2022)
Abstract Background Brain atrophy appears during the progression of multiple sclerosis (MS) and is associated with the disability caused by the disease. Methods We investigated global and regional grey matter (GM) and white matter (WM) volumes, WM le
Externí odkaz:
https://doaj.org/article/bb8159823d624d57b3c0b3703cef79aa
Autor:
Timo Tuovinen, Janne Kananen, Zalan Rajna, Johannes Lieslehto, Vesa Korhonen, Riikka Rytty, Heli Mattila, Niko Huotari, Lauri Raitamaa, Heta Helakari, Ahmed Abou Elseoud, Johanna Krüger, Pierre LeVan, Osmo Tervonen, Juergen Hennig, Anne M. Remes, Maiken Nedergaard, Vesa Kiviniemi
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Abstract Biomarkers sensitive to prodromal or early pathophysiological changes in Alzheimer’s disease (AD) symptoms could improve disease detection and enable timely interventions. Changes in brain hemodynamics may be associated with the main clini
Externí odkaz:
https://doaj.org/article/caee84f1ec8b4f068b3915608e8cac85
Autor:
Joel Räsänen, Joel Huovinen, Ville E. Korhonen, Antti Junkkari, Sami Kastinen, Simo Komulainen, Minna Oinas, Cecilia Avellan, Janek Frantzen, Jaakko Rinne, Antti Ronkainen, Mikko Kauppinen, Kimmo Lönnrot, Markus Perola, Anne M. Koivisto, Anne M. Remes, Hilkka Soininen, Mikko Hiltunen, Seppo Helisalmi, Mitja I. Kurki, Juha E. Jääskeläinen, Ville Leinonen
Publikováno v:
Fluids and Barriers of the CNS, Vol 17, Iss 1, Pp 1-11 (2020)
Abstract Background The pathophysiological basis of idiopathic normal pressure hydrocephalus (iNPH) is still unclear. Previous studies have shown a familial aggregation and a potential heritability when it comes to iNPH. Our aim was to conduct a nove
Externí odkaz:
https://doaj.org/article/5abbbab9d5b645c296624a57d3a0cc0e
Serum neurofilament light chain in FTLD: association with C9orf72, clinical phenotype, and prognosis
Autor:
Antti Cajanus, Kasper Katisko, Aleksi Kontkanen, Olli Jääskeläinen, Päivi Hartikainen, Annakaisa Haapasalo, Sanna‐Kaisa Herukka, Ritva Vanninen, Eino Solje, Anette Hall, Anne M. Remes
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 7, Iss 6, Pp 903-910 (2020)
Abstract Objective The aim of the present study was to compare the levels of serum neurofilament light chain (sNfL) in frontotemporal lobar degeneration (FTLD) patients of different clinical subtypes (bvFTD, PPA, and FTLD‐MND) and with or without t
Externí odkaz:
https://doaj.org/article/f38da3e0388342d48a3efb61e5c9fa1e
Autor:
Nadine Huber, Dorit Hoffmann, Raisa Giniatullina, Hannah Rostalski, Stina Leskelä, Mari Takalo, Teemu Natunen, Eino Solje, Anne M. Remes, Rashid Giniatullin, Mikko Hiltunen, Annakaisa Haapasalo
Publikováno v:
Neurobiology of Disease, Vol 162, Iss , Pp 105584- (2022)
Frontotemporal lobar degeneration (FTLD) comprises a heterogenous group of progressive neurodegenerative syndromes. To date, no validated biomarkers or effective disease-modifying therapies exist for the different clinical or genetic subtypes of FTLD
Externí odkaz:
https://doaj.org/article/0d8dcea9ac014ce6b915a51bc64162b9
Autor:
Marie Bruun, Kristian S. Frederiksen, Hanneke F. M. Rhodius-Meester, Marta Baroni, Le Gjerum, Juha Koikkalainen, Timo Urhemaa, Antti Tolonen, Mark van Gils, Daniel Rueckert, Nadia Dyremose, Birgitte B. Andersen, Afina W. Lemstra, Merja Hallikainen, Sudhir Kurl, Sanna-Kaisa Herukka, Anne M. Remes, Gunhild Waldemar, Hilkka Soininen, Patrizia Mecocci, Wiesje M. van der Flier, Jyrki Lötjönen, Steen G. Hasselbalch
Publikováno v:
Alzheimer’s Research & Therapy, Vol 11, Iss 1, Pp 1-11 (2019)
Abstract Background In clinical practice, it is often difficult to predict which patients with cognitive complaints or impairment will progress or remain stable. We assessed the impact of using a clinical decision support system, the PredictND tool,
Externí odkaz:
https://doaj.org/article/e6d0259039dc46d6a5e8c049faf11b34
Autor:
Sami Heikkinen, Nadine Huber, Kasper Katisko, Tarja Kokkola, Päivi Hartikainen, Johanna Krüger, Ville Leinonen, Ville E. Korhonen, Sanna-Kaisa Herukka, Anne M. Remes, Barbara Borroni, Antonella Alberici, Ilenia Libri, Eino Solje, Annakaisa Haapasalo
Publikováno v:
Journal of Alzheimer's Disease. 93:395-401
Frontotemporal dementia (FTD) can manifest as diverse clinical phenotypes and is frequently caused by mutations in different genes, complicating differential diagnosis. This underlines the urgent need for valid biomarkers. Altered lysosomal and immun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ff0fd1610a1fd1dc0a0bb6d9e2985b8
https://doi.org/10.3233/jad-221060
https://doi.org/10.3233/jad-221060