Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Anne M Powell"'
Autor:
Juan Carlos Izpisua Belmonte, Tianbin Liu, Laramie Pence, Anne M. Powell, Yue Shen, Jie Li, Jessica Bridge, Kyung Jun Uh, Ying Gu, Bhanu Prakash V.L. Telugu, Jun Wu, Luhui Zhang, Chi-Hun Park, Hai Xi Sun, Ki-Eun Park, Young Jeoung
Publikováno v:
Stem Cell Reports
Summary Most of our current knowledge regarding early lineage specification and embryo-derived stem cells comes from studies in rodent models. However, key gaps remain in our understanding of these developmental processes from nonrodent species. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e037af4f0f18493874da000938740132
http://europepmc.org/articles/PMC7897585
http://europepmc.org/articles/PMC7897585
Autor:
Laramie Pence, Juan Carlos Izpisua Belmonte, Yue Shen, Anne M. Powell, Ying Gu, Hai Xi Sun, Tianbin Liu, Bhanu Prakash V.L. Telugu, Jun Uh, Jessica Bridge, Jun Wu, Jie Li, Young Jeoung, Ki-Eun Park, Chi Park
In this article, we report for the first time the derivation and characterization of extra-embryonic endoderm (XEN) cells from primitive endoderm (PrE) of porcine (p) embryos. The pXEN cells can be reliably and reproducibly generated from parthenote,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0c3e747991d38070292e6f8610f15b7
https://doi.org/10.1101/2020.01.02.892802
https://doi.org/10.1101/2020.01.02.892802
Autor:
Timothy P Sheets, Anne M. Powell, Chi-Hun Park, Steven M. Swift, Ki-Eun Park, Bhanu Prakash V.L. Telugu, David M. Donovan
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Scientific Reports
Scientific Reports
The domestic pig is an attractive model for biomedical research because of similarities in anatomy and physiology to humans. However, key gaps remain in our understanding of the role of developmental genes in pig, limiting its full potential. In this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49152c8abdaa348a823077292a9a31ef
http://link.springer.com/article/10.1038/s41598-018-22050-0
http://link.springer.com/article/10.1038/s41598-018-22050-0
Autor:
Neil C. Talbot, Wesley M. Garrett, Anne M. Powell, Thomas J. Caperna, David M. Donovan, Le Ann Blomberg, Wendy O. Sparks, Alan D. Ealy, Caitlin E. Phillips
Publikováno v:
Molecular Reproduction and Development. 84:468-485
Thirteen independent induced bovine trophectroderm (iBT) cell lines were established by reprogramming bovine fetal liver-derived fibroblasts after viral-vector transduction with either six or eight factors, including POU5F1 (OCT4), KLF4, SOX2, MYC, N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7202a153010836a205aef36886cf95a1
https://doi.org/10.1002/mrd.22797
https://doi.org/10.1002/mrd.22797
Autor:
Anjali Nandal, L. A. Blomberg, Shelley E. S. Sandmaier, Neil C. Talbot, Bhanu Prakash V.L. Telugu, David M. Donovan, Anne M. Powell, Wesley M. Garrett
Publikováno v:
Molecular Reproduction and Development. 82:709-721
The creation of genetically modified goats provides a powerful approach for improving animal health, enhancing production traits, animal pharming, and for ensuring food safety all of which are high-priority goals for animal agriculture. The availabil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d323186ae8b6b956b55a374c6648dacb
https://doi.org/10.1002/mrd.22512
https://doi.org/10.1002/mrd.22512
Autor:
Alan J. Mileham, Le Ann Blomberg, Shelley E. S. Sandmaier, C. Bruce A. Whitelaw, Jon M. Oatley, Ki-Eun Park, Simon G. Lillico, Muhammad Salman Waqas, Anne M. Powell, Amy V. Kaucher, Melissa J. Oatley, Bhanu Prakash V.L. Telugu, Chi-Hun Park, Ahmed Tibary, David M. Donovan
Publikováno v:
Park, K-E, Kaucher, A V, Powell, A, Waqas, M S, Sandmaier, S E S, Oatley, M J, Park, C-H, Tibary, A, Donovan, D M, Blomberg, L A, Lillico, S, Whitelaw, C, Mileham, A, Telugu, B & Oatley, J M 2017, ' Generation of germline ablated male pigs by CRISPR/Cas9 editing of the NANOS2 gene ', Scientific Reports, vol. 7, 40176 . https://doi.org/10.1038/srep40176
Scientific Reports
Scientific Reports
Genome editing tools have revolutionized the generation of genetically modified animals including livestock. In particular, the domestic pig is a proven model of human physiology and an agriculturally important species. In this study, we utilized the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91a08902878ae39a264fd26a588dc47d
https://hdl.handle.net/20.500.11820/8bd727f6-a5c3-420a-bd21-d63f085dfa87
https://hdl.handle.net/20.500.11820/8bd727f6-a5c3-420a-bd21-d63f085dfa87
Autor:
Anne M. Powell, David M. Donovan, Chi-Hun Park, Ki-Eun Park, Timothy P Sheets, Bhanu Prakash V.L. Telugu
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 17, Iss 12, p 2031 (2016)
International Journal of Molecular Sciences, Vol 17, Iss 12, p 2031 (2016)
The domestic pig is an ideal “dual purpose” animal model for agricultural and biomedical research. With the availability of genome editing tools such as clustered regularly interspaced short palindromic repeat (CRISPR) and associated nuclease Cas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e33e9b8a989a1039b2c619ca11fb225c
http://europepmc.org/articles/PMC5187831
http://europepmc.org/articles/PMC5187831
Autor:
Neil C, Talbot, Wendy O, Sparks, Caitlin E, Phillips, Alan D, Ealy, Anne M, Powell, Thomas J, Caperna, Wesley M, Garrett, David M, Donovan, Le Ann, Blomberg
Publikováno v:
Molecular reproduction and development. 84(6)
Thirteen independent induced bovine trophectroderm (iBT) cell lines were established by reprogramming bovine fetal liver-derived fibroblasts after viral-vector transduction with either six or eight factors, including POU5F1 (OCT4), KLF4, SOX2, MYC, N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::75c190f60303c87d7788720852d7037f
https://pubmed.ncbi.nlm.nih.gov/28332752
https://pubmed.ncbi.nlm.nih.gov/28332752
Autor:
Anne M. Powell, Jessica Martin, Chi-Hun Park, Ki-Eun Park, Bhanu Prakash V.L. Telugu, David M. Donovan
Publikováno v:
International Journal of Molecular Sciences, Vol 17, Iss 6, p 810 (2016)
International Journal of Molecular Sciences; Volume 17; Issue 6; Pages: 810
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 17; Issue 6; Pages: 810
International Journal of Molecular Sciences
The pig is an ideal large animal model for genetic engineering applications. A relatively short gestation interval and large litter size makes the pig a conducive model for generating and propagating genetic modifications. The domestic pig also share
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e066ef210c79385072e5c7a5aa06048
http://www.mdpi.com/1422-0067/17/6/810
http://www.mdpi.com/1422-0067/17/6/810
Autor:
Anne M. Powell, Juli Foster-Frey, Jean C. Lee, David G. Pritchard, John Baker, Daniel C. Nelson, Stephen C. Becker, Homan Mohammadi, Yang Shen, Ian Marriott, David M. Donovan, Tamsin R. Sheen, Shengli Dong, Vinita S. Chauhan, Mathias Schmelcher, Gary R. Bauchan, William J. Harty, Richard A. Lease, Raul A. Almeida, Kelly S. Doran, Chad Simmons, Dwayne R. Roach, Mary J. Camp
Publikováno v:
Scientific Reports
Scientific Reports, 6
Scientific Reports, 6
Multi-drug resistant bacteria are a persistent problem in modern health care, food safety and animal health. There is a need for new antimicrobials to replace over used conventional antibiotics. Here we describe engineered triple-acting staphylolytic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1aee1982018f88eadaaef4c0b9d8992
https://doi.org/10.1038/srep25063
https://doi.org/10.1038/srep25063