Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Anne M Lynn"'
Publikováno v:
F1000Research, Vol 6 (2017)
This review focuses on pharmacokinetics and pharmacodynamics of opioid and non-opioid analgesics in neonates and infants. The unique physiology of this population differs from that of adults and impacts drug handling. Morphine and remifentanil are de
Externí odkaz:
https://doaj.org/article/f29c1ebbd0ff481cad421c392ae16e52
Autor:
Michiel J van Esdonk, Anne M. Lynn, Karel Allegaert, Dick Tibboel, Klaus T. Olkkola, Youssef Daali, Anne Smits, Michael E Cloesmeijer, Paola Mian
Publikováno v:
British Journal of Clinical Pharmacology, 87(3), 1443-1454. Wiley-Blackwell Publishing Ltd
British Journal of Clinical Pharmacology (2020)
British journal of clinical pharmacology, 87(3), 1443-1454. Wiley-Blackwell
British Journal of Clinical Pharmacology (2020)
British journal of clinical pharmacology, 87(3), 1443-1454. Wiley-Blackwell
AIMS: Ketorolac is a nonsteroidal anti-inflammatory racemic drug with analgesic effects only attributed to its S-enantiomer. The aim of this study is to quantify enantiomer-specific maturational pharmacokinetics (PK) of ketorolac and investigate if t
Autor:
Neil S. Morton, Geoff Frawley, Anne M. Lynn, Sarah J Arnup, Joss J. Thomas, Philip Ragg, Jurgen C. de Graaff, Girolamo Mattioli, Francesca Izzo, Davinia E. Withington, Alessio Pini Prato, Mary Ellen McCann, Peter Szmuk, Rodney W. Hunt, Andrew Davidson, Nicola Disma
Publikováno v:
Journal of Pediatric Surgery, 53(9), 1643-1650. W.B. Saunders
Background The GAS study is an international RCT to evaluate neurodevelopmental outcome comparing general plus regional anesthesia versus regional anesthesia alone in 722 neonates and infants who had inguinal hernia repair up to 60 weeks of postmenst
Autor:
Elliot J. Krane, Bonnie Stevens, Bernard P. Schachtel, Anne M. Lynn, Jennifer Stinson, Gary A. Walco, Srinivasa Raja, Dennis C. Turk, Paul J. Desjardins, Myron Yaster, Charles B. Berde, Ernest A. Kopecky, Lynne G. Maxwell, Robert H. Dworkin, Kanwaljeet J. S. Anand, Ian Gilron, Carlton Dampier, Steven J. Weisman
Publikováno v:
Pain. 159:193-205
Clinical trials to test the safety and efficacy of analgesics across all pediatric age cohorts are needed to avoid inappropriate extrapolation of adult data to children. However, the selection of acute pain models and trial design attributes to maxim
Publikováno v:
Colombian Journal of Anesthesiology. 45:72-79
Introduction Pharmacology of infants is understudied and different from other populations. Objective To review the unique features of neonatal and infant physiology that impact drug handling and the pharmacokinetics of analgesics, including opioids,
Autor:
Davinia E. Withington, Agnes Hunyady, Neil S. Morton, Sarah J Arnup, Katherine R. Gentry, Anne M. Lynn, Andrew Davidson, Jurgen C. de Graaff, Liam Dorris, Mary Ellen McCann, Nicola Disma
Publikováno v:
Paediatric Anaesthesia, 29(1), 51-58. Wiley-Blackwell Publishing Ltd
Introduction Randomized trials are important for generating high‐quality evidence, but are perceived as difficult to perform in the pediatric population. Thus far there has been poor characterization of the barriers to conducting trials involving c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2783bc4ab39e6d4748c26d3c427b7ca3
https://pure.eur.nl/en/publications/0e8927ee-8906-4c61-8cfc-0a471e27b8e2
https://pure.eur.nl/en/publications/0e8927ee-8906-4c61-8cfc-0a471e27b8e2
The Feasibility of Developing an Inpatient Acupuncture Program at a Tertiary Care Pediatric Hospital
Publikováno v:
The Journal of Alternative and Complementary Medicine. 22:458-464
Use of complementary and integrative health approaches has increased significantly in recent decades, with hospital-based acupuncture programs becoming more common. This article presents the feasibility of developing an inpatient acupuncture program
Autor:
Jose T D G Van Gool, David M. Polaner, Robyn Stargatt, Girolamo Mattioli, Niall C. T. Wilton, Greg Hammer, J. H M Hagenaars, Marie Backstrom, Davinia E. Withington, John B. Carlin, Navil F. Sethna, Martin Meuller, Val Gebski, Neil McIntosh, Iskra Ivanova, Philip Ragg, Penelope L Hartmann, Cor J. Kalkman, Sulpicio G. Soriano, Stephen R. Hays, Jonathan De Lima, Geoff Frawley, Gaia Giribaldi, Valter Sonzogni, Alessio Pini Prato, Pollyanna Hardy, Britta S von Ungern Sternberg, Sarah J Arnup, Annette J.M. Davis, Anthony Absalom, Ayman I. Eissa, Charles B. Berde, Nicola Disma, Vanessa Young, Giovanni Montobbio, Liam Dorris, Graham Bell, Francesca Izzo, Shilpa Verma, Jurgen C. de Graaff, Jeffery Steiner, Pietro Tuo, Graham Knottenbelt, Martin J. Volkers, Santhanam Suresh, David Costi, Peter A. Stoddart, Britta S. von Ungern-Sternberg, Joss J. Thomas, Koto Furue, Ida Salvo, Anne M. Lynn, Josee Gaudreault, Sandra Numan, Peter Szmuk, Bruno Guido Locatelli, David Field, Robert K. Williams, Pete G. Kovatsis, Katherine J Lee, Rodney W. Hunt, Andy Wolf, Paul S. Myles, Gillian D Ormond, Andrew Davidson, Oliver Bagshaw, Kate Leslie, Frouckje M. Hoekstra, Mary Ellen McCann, Agnes Hunyady, Anthony Chisakuta, Jacki Marmor, David C. Bellinger, Suzette Sheppard, Dick Tibboel, Denisa Haret, Leila Mameli, Neil S. Morton, Lynne G. Maxwell, Andreas H. Taenzer, Joseph P. Cravero, Andrea Wolfler, Magda Khotcholava, Claire Adey, Brian Kravitz
Publikováno v:
Anesthesiology. 123:38-54
Background:Postoperative apnea is a complication in young infants. Awake regional anesthesia (RA) may reduce the risk; however, the evidence is weak. The General Anesthesia compared to Spinal anesthesia study is a randomized, controlled trial designe
Autor:
Meindert Danhof, Caroline D. van der Marel, Joost DeJongh, Anne M. Lynn, Elke H. J. Krekels, Catherijne A. J. Knibbe, Richard A. van Lingen, Dick Tibboel, Imti Choonara
Publikováno v:
Clinical Pharmacokinetics, 50(1), 51-63. Adis
Background and Objective: Model validation procedures are crucial when models are to be used to develop new dosing algorithms. In this study, the predictive performance of a previously published paediatric population pharmacokinetic model for morphin