Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Anne M Hocking"'
Autor:
Sarah Alice Long, Virginia S. Muir, Britta E. Jones, Valerie Z. Wall, Alyssa Ylescupidez, Anne M. Hocking, Stephan Pribitzer, Jerill Thorpe, Bryce Fuchs, Alice E. Wiedeman, Megan Tatum, Katharina Lambert, Hannes Uchtenhagen, Cate Speake, Bernard Ng, Alexander T. Heubeck, Troy R. Torgerson, Adam K. Savage, Michael A. Maldonado, Neelanjana Ray, Vadim Khaychuk, Jinqi Liu, Peter S. Linsley, Jane H. Buckner
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Exhausted CD8 T cells (TEX) are associated with worse outcome in cancer yet better outcome in autoimmunity. Building on our past findings of increased TIGIT+KLRG1+ TEX with teplizumab therapy in type 1 diabetes (T1D), in the absence of treatment we f
Externí odkaz:
https://doaj.org/article/848afa4859044e9fb280078686f378e7
Autor:
Cate Speake, Tania Habib, Katharina Lambert, Christian Hundhausen, Sandra Lord, Matthew J. Dufort, Samuel O. Skinner, Alex Hu, MacKenzie Kinsman, Britta E. Jones, Megan D. Maerz, Megan Tatum, Anne M. Hocking, Gerald T. Nepom, Carla J. Greenbaum, Jane H. Buckner
Publikováno v:
JCI Insight, Vol 7, Iss 22 (2022)
Therapeutics that inhibit IL-6 at different points in its signaling pathway are in clinical use, yet whether the immunological effects of these interventions differ based on their molecular target is unknown. We performed short-term interventions in
Externí odkaz:
https://doaj.org/article/0d42c57eea354a0694720ed4803ef101
Autor:
Anne M. Hocking, Jane H. Buckner
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Genetic variants associated with susceptibility to autoimmune disease have provided important insight into the mechanisms responsible for the loss of immune tolerance and the subsequent development of autoantibodies, tissue damage, and onset of clini
Externí odkaz:
https://doaj.org/article/3a0ad08f2b4f49fab9ca5e8505062f96
Autor:
Katharina Lambert, Kirsten E. Diggins, Britta E. Jones, Christian Hundhausen, Megan D. Maerz, Anne M. Hocking, Srinath Sanda, Carla J. Greenbaum, Peter S. Linsley, Karen Cerosaletti, Jane H. Buckner
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Elevated levels and enhanced sensing of the pro-inflammatory cytokine interleukin-6 (IL-6) are key features of many autoimmune and inflammatory diseases. To better understand how IL-6 signaling may influence human T cell fate, we investigated the rel
Externí odkaz:
https://doaj.org/article/c773700586e44a7c8cb9899ec2c188f9
Autor:
Elizabeth M. Dam, Alison C. Maier, Anne M. Hocking, Jeffrey Carlin, Bernard Ng, Jane H. Buckner
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Externí odkaz:
https://doaj.org/article/ba38499c084247b68fa6c1afb6a9aa34
Autor:
Elizabeth M. Dam, Alison C. Maier, Anne M. Hocking, Jeffrey Carlin, Bernard Ng, Jane H. Buckner
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
B cells are implicated in rheumatoid arthritis (RA) based on the presence of autoantibodies and the therapeutic response to B cell depletion. IL-21 has a significant role in B cell development and function. Here we assess B cell responses to IL-21 an
Externí odkaz:
https://doaj.org/article/9f5a281c47bb45ed80faf554bcd8b6bd
Autor:
Pornthep Sirimahachaiyakul, Ravi F Sood, Lara A Muffley, Max Seaton, Cheng-Ta Lin, Liang Qiao, Jeffrey S Armaly, Anne M Hocking, Nicole S Gibran
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0139135 (2015)
Abnormal pigmentation following cutaneous injury causes significant patient distress and represents a barrier to recovery. Wound depth and patient characteristics influence scar pigmentation. However, we know little about the pathophysiology leading
Externí odkaz:
https://doaj.org/article/2140f07b8b974249ae5ceb6e2cb3b7ee
Autor:
Alyssa Ylescupidez, Aaron Rips, Cate Speake, Uma Malhotra, Anne M. Hocking, Punam Verma, Henry T. Bahnson, Jane H. Buckner
Publikováno v:
Journal of Clinical Medicine
Journal of Clinical Medicine, Vol 10, Iss 1562, p 1562 (2021)
Volume 10
Issue 8
Journal of Clinical Medicine, Vol 10, Iss 1562, p 1562 (2021)
Volume 10
Issue 8
Comprehensive data on early prognostic indicators in patients with mild COVID-19 remains sparse. In this single center case series, we characterized the initial clinical presentation in 180 patients with mild COVID-19 and defined the earliest predict
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4df56c356447f7ddcda9be8a69d709b3
http://europepmc.org/articles/PMC8068070
http://europepmc.org/articles/PMC8068070
Autor:
Cate Speake, Daniel J. Campbell, Hamid Bolouri, Anne M. Hocking, Jane H. Buckner, David A. G. Skibinski, Uma Malhotra, S. Alice Long, Jessica A. Hamerman
Publikováno v:
J Clin Invest
BACKGROUND: Despite a rapidly growing body of literature on coronavirus disease 2019 (COVID-19), our understanding of the immune correlates of disease severity, course, and outcome remains poor. METHODS: Using mass cytometry, we assessed the immune l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6277fdd55df89d7e45566abb19c67b86
https://doi.org/10.1172/jci143648
https://doi.org/10.1172/jci143648
Autor:
Loren H Engrav, Christopher K Tuggle, Kathleen F Kerr, Kathy Q Zhu, Surawej Numhom, Oliver P Couture, Richard P Beyer, Anne M Hocking, Gretchen J Carrougher, Maria Luiza C Ramos, Matthew B Klein, Nicole S Gibran
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e19024 (2011)
Hypertrophic scar was first described over 100 years ago; PubMed has more than 1,000 references on the topic. Nevertheless prevention and treatment remains poor, because 1) there has been no validated animal model; 2) human scar tissue, which is impo
Externí odkaz:
https://doaj.org/article/625a4da5f10043c48dd75ef13b6b72c6