Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Anne M, Manicone"'
Autor:
Mithu De, Gregory Serpa, Eryn Zuiker, Katherine B. Hisert, W. Conrad Liles, Anne M. Manicone, Emily A. Hemann, Matthew E. Long
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
Chronic pulmonary bacterial infections and associated inflammation remain a cause of morbidity and mortality in people with cystic fibrosis (PwCF) despite new modulator therapies. Therapies targeting host factors that dampen detrimental inflammation
Externí odkaz:
https://doaj.org/article/27d876f7f26041368b9612c3659d7983
Autor:
Eric D. Morrell, Carmen Mikacenic, Ke-Qin Gong, Susanna Kosamo, Mark M. Wurfel, Anne M. Manicone
Publikováno v:
Critical Care, Vol 24, Iss 1, Pp 1-3 (2020)
Externí odkaz:
https://doaj.org/article/63c403335aba45f1ba1d10549aa6beb8
Autor:
Katherine B. Hisert, Timothy P. Birkland, Kelly Q. Schoenfelt, Matthew E. Long, Brenda Grogan, Suzanne Carter, W. Conrad Liles, Edward F. McKone, Lev Becker, Anne M. Manicone, Sina A. Gharib
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
BackgroundCFTR modulators decrease some etiologies of CF airway inflammation; however, data indicate that non-resolving airway infection and inflammation persist in individuals with CF and chronic bacterial infections. Thus, identification of therapi
Externí odkaz:
https://doaj.org/article/9bb3386b6d0b477b94c2d15b5d6ad5b6
Autor:
Katherine B. Hisert, Timothy P. Birkland, Kelly Q. Schoenfelt, Matthew E. Long, Brenda Grogan, Suzanne Carter, W. Conrad Liles, Edward F. McKone, Lev Becker, Anne M. Manicone
Publikováno v:
ERJ Open Research, Vol 6, Iss 2 (2020)
Externí odkaz:
https://doaj.org/article/9c0b01d418b14e5a8714aa95b00b6846
Publikováno v:
Pneumonia, Vol 9, Iss 1, Pp 1-6 (2017)
Abstract This study was designed to test the therapeutic potential of a MEK1/2 inhibitor (MEKi) in an experimental model of Pseudomonas aeruginosa pneumonia. The study found that treatment with MEKi reduced alveolar neutrophilic inflammation and led
Externí odkaz:
https://doaj.org/article/97d65796e1a24f3db196198008b5004c
Autor:
Hrishikesh S. Kulkarni, Janet S. Lee, Julie A. Bastarache, Wolfgang M. Kuebler, Gregory P. Downey, Guillermo M. Albaiceta, William A. Altemeier, Antonio Artigas, Jason H. T. Bates, Carolyn S. Calfee, Charles S. Dela Cruz, Robert P. Dickson, Joshua A. Englert, Jeffrey I. Everitt, Michael B. Fessler, Andrew E. Gelman, Kymberly M. Gowdy, Steve D. Groshong, Susanne Herold, Robert J. Homer, Jeffrey C. Horowitz, Connie C. W. Hsia, Kiyoyasu Kurahashi, Victor E. Laubach, Mark R. Looney, Rudolf Lucas, Nilam S. Mangalmurti, Anne M. Manicone, Thomas R. Martin, Sadis Matalon, Michael A. Matthay, Daniel F. McAuley, Sharon A. McGrath-Morrow, Joseph P. Mizgerd, Stephanie A. Montgomery, Bethany B. Moore, Alexandra Noël, Carrie E. Perlman, John P. Reilly, Eric P. Schmidt, Shawn J. Skerrett, Tomeka L. Suber, Charlotte Summers, Benjamin T. Suratt, Masao Takata, Rubin Tuder, Stefan Uhlig, Martin Witzenrath, Rachel L. Zemans, Gutavo Matute-Bello
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 66:e1-e14
Autor:
Coralynn S, Sack, Anne M, Manicone
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 205:978-980
Autor:
Ke-Qin Gong, Carmen Mikacenic, Matthew E. Long, Charles W. Frevert, Timothy P. Birkland, Jean Charron, Sina A. Gharib, Anne M. Manicone
Publikováno v:
Am J Respir Cell Mol Biol
Acute respiratory distress syndrome (ARDS) remains a significant problem in need of new pharmaceutical approaches to improve its resolution. Studies comparing gene expression signatures in rodents and humans with lung injury reveal conserved pathways
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c077b33f079efa12b204499995ea5149
https://europepmc.org/articles/PMC9116357/
https://europepmc.org/articles/PMC9116357/
Autor:
Carmen Mikacenic, Sina A. Gharib, Eric D. Morrell, Anne M. Manicone, Frank Radella, Mark M. Wurfel, Renee D. Stapleton, Pavan K. Bhatraju
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 200:732-741
Rationale: Serial measurements of alveolar macrophage (AM) transcriptional changes in patients with acute respiratory distress syndrome (ARDS) could identify cell-specific biological programs that ...
Autor:
William E. Eddy, Anne M. Manicone, Moira L. Aitken, Sina A. Gharib, William C. Parks, Matthew E. Long, Ryan S. McMahan
Publikováno v:
Journal of Allergy and Clinical Immunology. 143:1536-1548
Background Macrophage plasticity allows cells to adopt different phenotypes, a property with important implications in disorders such as cystic fibrosis (CF) and asthma. Objective We sought to examine the transcriptional and functional significance o