Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Anne M, Horne"'
Autor:
Kazi Mirajul Hoque, Eryn E. Dixon, Raychel M. Lewis, Jordyn Allan, Gregory D. Gamble, Amanda J. Phipps-Green, Victoria L. Halperin Kuhns, Anne M. Horne, Lisa K. Stamp, Tony R. Merriman, Nicola Dalbeth, Owen M. Woodward
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
The common ABCG2 variant Q141K contributes to hyperuricemia and gout risk. Here, using a human interventional study and a new orthologous mouse model, the authors report a tissue specific pathobiology of the Q141K variant, and support a significant r
Externí odkaz:
https://doaj.org/article/12c73f6333324432b9f2c84850631506
Autor:
Rachel Murdoch, Anna Mellar, Anne M. Horne, Emma Billington, Pui Ling Chan, Gregory D. Gamble, Ian R. Reid
Publikováno v:
Journal of Bone and Mineral Research. 38:631-638
Publikováno v:
British Journal of Clinical Pharmacology. 89:1099-1104
The aim of this work is to assess the safety and efficacy of two oral zoledronate preparations by determining their effects on bone resorption in healthy postmenopausal women.The preparations studied were zoledronic acid in enteric-coated capsules or
Publikováno v:
Journal of Bone and Mineral Research. 37:2149-2155
Vertebral fractures are associated with height loss, reduced quality of life, and increased mortality and are an important endpoint for osteoporosis trials. However, height loss is associated with quality of life and mortality independent of associat
Publikováno v:
Bone Reports, Vol 10, Iss , Pp - (2019)
Longitudinal studies often report that spine bone mineral density (BMD), measured by DXA, is stable in older adults, which has been attributed to osteophyte development and the presence of aortic calcification. A decline in projected spine area as a
Externí odkaz:
https://doaj.org/article/0bb5e23bf2c744b982e0f8159790a222
Autor:
Rachel Murdoch, Borislav Mihov, Anne M. Horne, Keith J. Petrie, Gregory D. Gamble, Nicola Dalbeth
Publikováno v:
Arthritis Care & Research.
Autor:
George B. Coleman, Nicola Dalbeth, Chris Frampton, Janine Haslett, Jill Drake, Isabel Su, Anne M. Horne, Lisa K. Stamp
Publikováno v:
The Journal of rheumatology. 49(12)
ObjectiveTo determine the long-term use of and adherence to urate-lowering therapy (ULT), serum urate (SU) control, and self-reported flares in participants from a randomized controlled trial of allopurinol dose escalation, in order to achieve target
Autor:
Ian R, Reid, Anne M, Horne, Borislav, Mihov, Angela, Stewart, Sonja, Bastin, Gregory D, Gamble
Publikováno v:
Calcified tissue international. 109(1)
A recent observational study of the incidence of pneumonia in patients with previous hip fractures found that bisphosphonate use reduced pneumonia risk by about one-quarter, in comparisons with those either not receiving osteoporosis treatment or rec
Autor:
Kazi Mirajul, Hoque, Eryn E, Dixon, Raychel M, Lewis, Jordyn, Allan, Gregory D, Gamble, Amanda J, Phipps-Green, Victoria L, Halperin Kuhns, Anne M, Horne, Lisa K, Stamp, Tony R, Merriman, Nicola, Dalbeth, Owen M, Woodward
Publikováno v:
Nature communications. 11(1)
The pathophysiological nature of the common ABCG2 gout and hyperuricemia associated variant Q141K (rs2231142) remains undefined. Here, we use a human interventional cohort study (ACTRN12615001302549) to understand the physiological role of ABCG2 and