Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Anne M, Glazier"'
Autor:
Martin Hrabé de Angelis, Morag A. Lewis, Anton J. Enright, Karen P. Steel, Stijn van Dongen, Cordelia Langford, Tamas Dalmay, Anne M Glazier, Nick Redshaw, Cei Abreu-Goodger, M A Moreno-Pelayo, Elizabeth Quint, Helmut Fuchs, Matias Piipari
Publikováno v:
Nature genetics
Progressive hearing loss is common in the human population, but little is known about the molecular basis. We report a new N-ethyl-N-nitrosurea (ENU)-induced mouse mutant, diminuendo, with a single base change in the seed region of Mirn96. Heterozygo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c21de3e5c44470e6fe38ff5f70860a76
http://europepmc.org/articles/PMC2705913
http://europepmc.org/articles/PMC2705913
Publikováno v:
Science. 298:2345-2349
Phenotypic variation among organisms is central to evolutionary adaptations underlying natural and artificial selection, and also determines individual susceptibility to common diseases. These types of complex traits pose special challenges for genet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b9993c92b8fdb5402f83be848df0959
https://doi.org/10.1126/science.1076641
https://doi.org/10.1126/science.1076641
Autor:
John Reynolds, Ccharles D Pusey, Timothy J. Aitman, Paul R. Cook, Mark A Duda, Anne M. Glazier, Penny J. Norsworthy, David J. Evans, James J. Ryan
Publikováno v:
Nephron Experimental Nephrology. 10:402-407
Experimental autoimmune glomerulonephritis (EAG), an animal model of Goodpasture’s disease, can be induced in Wistar-Kyoto (WKY) rats (RT1-l) by immunization with rat glomerular basement membrane (GBM) in adjuvant. The model in this rat strain is c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5df6f89e2f92c2d2e56aead7d7ee5020
https://doi.org/10.1159/000065297
https://doi.org/10.1159/000065297
Autor:
Douglas D. Ebert, Timothy J. Aitman, Richard H. Aster, Saira Ali, Brian R. Curtis, Anne M. Glazier
Publikováno v:
Transfusion. 42:1173-1179
BACKGROUND : Platelet CD36 (glycoprotein [GP] IV) deficiency occurs in 3 to 5 percent of persons of Asian or African ancestry. A subset of these individuals is at risk for immunization against CD36, but the magnitude of this problem and its significa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a690026b68b117473f00803af0537d49
https://doi.org/10.1046/j.1537-2995.2002.00176.x
https://doi.org/10.1046/j.1537-2995.2002.00176.x
Autor:
Danilo C. Carlos, Tom C. Freeman, Saira Ali, Timothy J. Aitman, Anne E. Kwitek, Lawrence W. Stanton, Caroline A. Wallace, Penny J. Norsworthy, Anne M. Glazier, James Scott
Publikováno v:
Mammalian Genome. 13:194-197
The spontaneously hypertensive rat (SHR) is a model of human essential hypertension. Increased blood pressure in SHR is associated with other risk factors associated with cardiovascular disease, including insulin resistance and dyslipidemia. DNA micr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1780c5b3101c768490fa65fd8b3bcc76
https://doi.org/10.1007/s00335-001-2140-9
https://doi.org/10.1007/s00335-001-2140-9
Autor:
Azeddine Ibrahimi, Landa, St Lezin Em, Ludmila Kazdova, Alena Musilova, Theodore W. Kurtz, Zídek, N. Qi, Anne M. Glazier, Timothy J. Aitman, Nada A. Abumrad, Kren, M Pravenec, J M Wang
Publikováno v:
Nature Genetics. 27:156-158
Spontaneously hypertensive rats (SHR) display several features of the human insulin-resistance syndromes. Cd36 deficiency is genetically linked to insulin resistance in SHR. We show that transgenic expression of Cd36 in SHR ameliorates insulin resist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acf62d402027c9be2d4abe5824c5dc7a
https://doi.org/10.1038/84777
https://doi.org/10.1038/84777
Publikováno v:
Biometrics. 62(1)
We present a Bayesian hierarchical model for detecting differentially expressing genes that includes simultaneous estimation of array effects, and show how to use the output for choosing lists of genes for further investigation. We give empirical evi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c45696bb2a4e0753db05ed4c040f1bde
https://pubmed.ncbi.nlm.nih.gov/16542224
https://pubmed.ncbi.nlm.nih.gov/16542224
Autor:
John, Reynolds, Paul R, Cook, James J, Ryan, Penny J, Norsworthy, Anne M, Glazier, Mark A, Duda, David J, Evans, Timothy J, Aitman, Ccharles D, Pusey
Publikováno v:
Experimental nephrology. 10(5-6)
Experimental autoimmune glomerulonephritis (EAG), an animal model of Goodpasture's disease, can be induced in Wistar-Kyoto (WKY) rats (RT1-l) by immunization with rat glomerular basement membrane (GBM) in adjuvant. The model in this rat strain is cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1e2b2cc4c7fe943065435d26df21c61f
https://pubmed.ncbi.nlm.nih.gov/12381925
https://pubmed.ncbi.nlm.nih.gov/12381925
Publikováno v:
Mammalian genome : official journal of the International Mammalian Genome Society. 13(2)
The human insulin resistance syndromes---type 2 diabetes, obesity, combined hyperlipidemia, and essential hypertension---are genetically complex disorders whose molecular basis is largely unknown. The spontaneously hypertensive rate (SHR) is a model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6948bf646dbe4c26a3771c9dc0fbef33
https://pubmed.ncbi.nlm.nih.gov/11889559
https://pubmed.ncbi.nlm.nih.gov/11889559
Autor:
James J. Morton, Anne M. Glazier, Delyth Graham, Timothy J. Aitman, Marek H. Dominiczak, Gwyn W. Gould, Anna F. Dominiczak, M. Collison, John M. C. Connell
Publikováno v:
Diabetes. 49(12)
Insulin resistance is of pathogenic importance in several common human disorders including type 2 diabetes, hypertension, obesity and hyperlipidemia, but the underlying mechanisms are unknown. The spontaneously hypertensive rat (SHR) is a model of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6994fdeb247efe9939eaeb1b26a2773d
https://pubmed.ncbi.nlm.nih.gov/11118030
https://pubmed.ncbi.nlm.nih.gov/11118030