Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Anne Louise Latif"'
Autor:
Gloria Iacoboni, Josu Iraola‐Truchuelo, Maeve O'Reilly, Víctor Navarro, Tobias Menne, Mi Kwon, Ana África Martín‐López, Sridhar Chaganti, Javier Delgado, Claire Roddie, Ariadna Pérez, Jane Norman, Manuel Guerreiro, Adam Gibb, Ana Carolina Caballero, Caroline Besley, Nuria Martínez‐Cibrián, Alberto Mussetti, Robin Sanderson, Hugo Luzardo, Sunil Iyengar, Jose Maria Sánchez, Ceri Jones, Juan‐Manuel Sancho, Pere Barba, Anne‐Louise Latif, Lucia López‐Corral, Rafael Hernani, Juan Luis Reguera, Anna Sureda, Alejandro Martin Garcia‐Sancho, Mariana Bastos, Pau Abrisqueta, Andrea Kuhnl
Publikováno v:
HemaSphere, Vol 8, Iss 5, Pp n/a-n/a (2024)
Abstract Over 60% of relapsed/refractory (R/R) large B‐cell lymphoma (LBCL) patients who receive chimeric antigen receptor (CAR) T cells will experience disease progression. There is no standard next line of therapy and information in this setting
Externí odkaz:
https://doaj.org/article/da69c64401f4489eb88ab02b2a46bb49
Autor:
Anne-Louise Latif, Ashley Newcombe, Sha Li, Kathryn Gilroy, Neil A. Robertson, Xue Lei, Helen J. S. Stewart, John Cole, Maria Terradas Terradas, Loveena Rishi, Lynn McGarry, Claire McKeeve, Claire Reid, William Clark, Joana Campos, Kristina Kirschner, Andrew Davis, Jonathan Lopez, Jun-ichi Sakamaki, Jennifer P. Morton, Kevin M. Ryan, Stephen W. G. Tait, Sheela A. Abraham, Tessa Holyoake, Brian Higgins, Xu Huang, Karen Blyth, Mhairi Copland, Timothy J. T. Chevassut, Karen Keeshan, Peter D. Adams
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
MDM2 and BET inhibitors have shown efficacy in AML treatment. Here, the authors show that the two compounds can synergize through both p53 protein stabilization and inhibition of BRD4-mediated repression of p53 target genes.
Externí odkaz:
https://doaj.org/article/4058dbf2924543a399c2f17c8fd2a6ad
Autor:
Jad Othman, Ing S Tiong, Katya Mokretar, Adam Ivey, Michael James Austin, Anne-Louise Latif, Charles Crawley, Mariam Amer, Francesca Crolla, Joe W Cross, Raymond Dang, Chun Yew Fong, Sofia Galli, Paolo Gallipoli, Francesca L Hogan, Pallavi Kalkur, Anjum Khan, Pramila Krishnamurthy, John Laurie, Scott R. Marshall, Vidhya Murthy, Sateesh K. Nagumantry, Srinivas Pillai, Nicola Potter, Tom Taylor, Rui Zhao, Andrew H Wei, Richard Dillon
Publikováno v:
Blood. 140:2033-2035
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4d80c040e79fbc9be9c49d2886572c9
https://doi.org/10.1182/blood-2022-159467
https://doi.org/10.1182/blood-2022-159467
Autor:
Stephen Boyle, Robin Sanderson, Maeve A. O'Reilly, Tobias F. Menne, Jane Norman, Adrian Bloor, Sanne Lugthart, Sridhar Chaganti, Carlos Gonzalez-Arias, Ceri Jones, Anne-Louise Latif, Reuben Benjamin, Piers Patten, Deborah Yallop, Victoria Potter, Claire Roddie, Andrea Kuhnl
Publikováno v:
Blood. 140:4649-4651
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a98f0e09a0fdc85e27463a4d2dcaa447
https://doi.org/10.1182/blood-2022-159217
https://doi.org/10.1182/blood-2022-159217
A national service for delivering CD19 CAR‐T in large B‐cell lymphoma – The UK real‐world experience
Autor:
Andrea Kuhnl, Claire Roddie, Amy A. Kirkwood, Eleni Tholouli, Tobias Menne, Amit Patel, Caroline Besley, Sridhar Chaganti, Robin Sanderson, Maeve O'Reilly, Jane Norman, Wendy Osborne, Adrian Bloor, Sanne Lugthart, Ram Malladi, Piers E. M. Patten, Lorna Neill, Nuria Martinez‐Cibrian, Hannah Kennedy, Elizabeth H. Phillips, Ceri Jones, Kirsty Sharplin, Dima El‐Sharkawi, Anne‐Louise Latif, Amrith Mathew, Benjamin Uttenthal, Orla Stewart, Maria A. V. Marzolini, William Townsend, Kate Cwynarski, Kirit Ardeshna, Arzhang Ardavan, Kate Robinson, Antonio Pagliuca, Graham P. Collins, Roderick Johnson, Andrew McMillan
Publikováno v:
British Journal of Haematology. 198:492-502
CD19 CAR-T have emerged as a new standard treatment for relapsed/refractory (r/r) large B-cell lymphoma (LBCL). CAR-T real-world (RW) outcomes published to date suggest significant variability across countries. We provide results of a large national
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::017628ccff28172fef0cf1f897295514
https://doi.org/10.1111/bjh.18209
https://doi.org/10.1111/bjh.18209
Autor:
Jad Othman, Nicola Potter, Katya Mokretar, David Taussig, Anjum Khan, Pramila Krishnamurthy, Anne-Louise Latif, Paul Cahalin, James Aries, Mariam Amer, Edward Belsham, Eibhlin Conneally, Charles Craddock, Dominic Culligan, Mike Dennis, Caroline Duncan, Caroline Furness, Paraskevi Gkreka, Katherine Hodgson, Wendy Ingram, Andrew King, Panagiotis Kottaridis, Mary Frances McMullin, Unmesh Mohite, Loretta Ngu, Katharine Patrick, Tom Rider, Wing Roberts, Marianne Tang Severinsen, Neill Storrar, Tom Taylor, Nigel H. Russell, Richard Dillon
Publikováno v:
Othman, J, Potter, N, Mokretar, K, Taussig, D, Khan, A, Krishnamurthy, P, Latif, A-L, Cahalin, P, Aries, J, Amer, M, Belsham, E, Conneally, E, Craddock, C, Culligan, D, Dennis, M, Duncan, C, Furness, C, Gkreka, P, Hodgson, K, Ingram, W, King, A, Kottaridis, P, McMullin, M F, Mohite, U, Ngu, L, Patrick, K, Rider, T, Roberts, W, Severinsen, M T, Storrar, N, Taylor, T, Russell, N H & Dillon, R 2022, ' High Molecular Response Rate and Overall Survival with FLT3 Inhibitors As MRD-Guided Salvage Treatment for Molecular Failure in AML ', Blood, vol. 140, no. Suppl. 1, pp. 2002-2004 . https://doi.org/10.1182/blood-2022-159503
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aeb6a16ee27d3d93605e5769abdec6c3
https://vbn.aau.dk/da/publications/35c706f6-65ae-417e-b628-07e99eb4f6e9
https://vbn.aau.dk/da/publications/35c706f6-65ae-417e-b628-07e99eb4f6e9
Autor:
David Irvine, Anne Louise Latif, Matthew Wilson, Gillian A. Horne, Jennifer Laird, Kenneth W. Douglas
Publikováno v:
Journal of Clinical Apheresis. 36:513-515
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3a73687a9c73b52be7d913d0e3c00f9
https://doi.org/10.1002/jca.21871
https://doi.org/10.1002/jca.21871
Autor:
Andrew Davis, Helen Stewart, Kristina Kirschner, Tessa L. Holyoake, William C. Clark, Ashley Newcombe, Xu Huang, John J. Cole, Anne-Louise Latif, Joana Campos, Stephen W.G. Tait, Kevin M. Ryan, Lynn McGarry, Loveena Rishi, Claire Reid, Jun-ichi Sakamaki, Sheela A. Abraham, Brian Higgins, Claire McKeeve, Xue Lei, Neil Robertson, Karen Blyth, Jennifer P. Morton, Timothy Chevassut, Mhairi Copland, Jonathan Lopez, Kathryn Gilroy, Karen Keeshan, Peter D. Adams, Sha Li, Maria Terradas Terradas
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Acute myeloid leukemia (AML) is a typically lethal molecularly heterogeneous disease, with few broad-spectrum therapeutic targets. Unusually, most AML retain wild-type TP53, encoding the pro-apoptotic tumor suppressor p53. MDM2 inhibitors (MDM2i), wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::813a0a41aaea00f9398f4b139324ead4
https://doi.org/10.1101/2020.09.16.291930
https://doi.org/10.1101/2020.09.16.291930
Autor:
R. Campbell Tait, Sarah K Westbury, Dirk Hendriks, Kate Downes, Claire S. Whyte, Andrew D Mumford, Nicola J. Mutch, Jonathan Stephens, Karen Claesen, Nihr BioResource, Ernest Turro, Joachim C. Mertens, Emma J Leishman, Anne-Louise Latif
Publikováno v:
Westbury, S K, Whyte, C S, Stephens, J, Downes, K, Turro, E, Claesen, K, Mertens, J, Hendriks, D, Latif, A-L, Leishman, E, Mutch, N J & Tait, C R & Mumford, A D 2020, ' A new pedigree with thrombomodulin-associated coagulopathy in which delayed fibrinolysis is partially attenuated by co-inherited TAFI deficiency ', Journal of Thrombosis and Haemostasis . https://doi.org/10.1111/jth.14990
Journal of thrombosis and haemostasis
Journal of thrombosis and haemostasis
Background: Thrombomodulin-associated coagulopathy (TM-AC) is a rare bleeding disorder in which a single reported p.Cys537* variant in the thrombomodulin gene THBD causes high plasma thrombomodulin (TM) levels. High TM levels attenuate thrombin gener
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c157a370d0e881f53aa770a2ad3679b4
https://research-information.bris.ac.uk/en/publications/6789ca66-5e8d-46c1-99cc-29e55d539469
https://research-information.bris.ac.uk/en/publications/6789ca66-5e8d-46c1-99cc-29e55d539469
Autor:
Amrith Mathew, Anne-Louise Latif, Charlotte Stenson, Eleni Tholouli, Lorna Neill, Sridhar Chaganti, Lourdes Rubio, Katarzyna Aleksandra Aleksandra Jalowiec, Emma Nicholson, Maeve A O'Reilly, Caroline Besley, Kathleen Pao Lynn Cheok, R. Sanderson, Claire Roddie, Andrea Kuhnl, Amit R. Patel, Kirsty Sharplin, Tobias Menne, Jessica Bazin, Ceri Jones
Publikováno v:
Blood. 138:531-531
Background Axicabtagene ciloleucel (axi-cel) and tisagenlecleucel (tisa-cel) CD19 CAR-T therapies are licensed in the UK for relapsed/refractory large B-cell lymphoma (LBCL). Corticosteroids for CAR-T toxicity were administered to 28% and 10% of pati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7cb68f184fc286ac8c4204a3c35740b5
https://doi.org/10.1182/blood-2021-149501
https://doi.org/10.1182/blood-2021-149501