Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Anne Lespine"'
Publikováno v:
Parasites & Vectors, Vol 15, Iss 1, Pp 1-12 (2022)
Abstract Background Dirofilaria immitis causes dirofilariosis, a potentially fatal condition in canids. Dirofilaria infections can be prevented with a macrocyclic lactone (ML) prophylactic regimen. However, some D. immitis isolates have become resist
Externí odkaz:
https://doaj.org/article/ad0c586b1a0547fc8ba9e3d76e3c197c
Autor:
Rémy Bétous, Anthony Emile, Hua Che, Eva Guchen, Didier Concordet, Thavy Long, Sandra Noack, Paul M Selzer, Roger Prichard, Anne Lespine
Publikováno v:
PLoS Pathogens, Vol 19, Iss 6, p e1011462 (2023)
Nematode parasites enter their definitive host at the developmentally arrested infectious larval stage (iL3), and the ligand-dependent nuclear receptor DAF-12 contributes to trigger their development to adulthood. Here, we characterized DAF-12 from t
Externí odkaz:
https://doaj.org/article/0212e8c062b941028f67aae478da276b
Autor:
Nico Hachgenei, Guillaume Nord, Lorenzo Spadini, Henri Mora, François Courvoisier, Jean‐François Sutra, Jean‐Pierre Vandervaere, Cédric Legoût, Marie‐Christine Morel, Jean Martins, Anne Lespine, Celine Duwig
Publikováno v:
Vadose Zone Journal, Vol 21, Iss 2, Pp n/a-n/a (2022)
Abstract Many contaminants of agricultural origin are released into rural environments, particularly at the soil surface. Their fate has been extensively investigated in repacked soils, but only few studies have addressed their transport in structura
Externí odkaz:
https://doaj.org/article/e06cfef989424e599069954a314210f4
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Abstract Prevention therapy against Dirofilaria immitis in companion animals is currently threatened by the emergence of isolates resistant to macrocyclic lactone anthelmintics. Understanding the control over developmental processes in D. immitis is
Externí odkaz:
https://doaj.org/article/108c836ccade4cb094a7790f86b21298
Autor:
Olivier Chosidow, Charlotte Bernigaud, Didier Guillemot, Bruno Giraudeau, Anne Lespine, Jean-Pierre Changeux, Hervé Bourhy, Marc Lecuit, Zahir Amoura
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 6, p e0009446 (2021)
Externí odkaz:
https://doaj.org/article/4d90369e899c41f4b6fbcd602a2c33f6
Autor:
Alain Bousquet-Mélou, Anne Lespine, Jean-François Sutra, Isabelle Bargues, Pierre-Louis Toutain
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Ivermectin (IVM) and moxidectin (MOX) are used extensively as parasiticides in veterinary medicine. Based on in vitro data, IVM has recently been proposed for the prevention and treatment of COVID-19 infection, a condition for which obesity is a majo
Externí odkaz:
https://doaj.org/article/b3dce9ffaffe404093de3b88cbbf580f
Autor:
Marion David, Chantal Lebrun, Thomas Duguet, Franck Talmont, Robin Beech, Stéphane Orlowski, François André, Roger K. Prichard, Anne Lespine
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 8, Iss 1, Pp 145-157 (2018)
Haemonchus contortus, one of the most economically important parasites of small ruminants, has become resistant to the anthelmintic ivermectin. Deciphering the role of P-glycoproteins in ivermectin resistance is desirable for understanding and overco
Externí odkaz:
https://doaj.org/article/8c003bc3fbe248e0b8a0a3cf2f63c38a
Autor:
Marion A. David, Stéphane Orlowski, Roger K. Prichard, Shaima Hashem, François André, Anne Lespine
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 6, Iss 3, Pp 299-313 (2016)
Macrocyclic lactones (ML) are important anthelmintics used in animals and humans against parasite nematodes, but their therapeutic success is compromised by the spread of ML resistance. Some ABC transporters, such as p-glycoproteins (Pgps), are selec
Externí odkaz:
https://doaj.org/article/9d45ccc23b7c4c02a52cfe442399e918
Autor:
Cécile Ménez, Mélanie Alberich, Elise Courtot, Fabrice Guegnard, Alexandra Blanchard, Hugo Aguilaniu, Anne Lespine
Publikováno v:
PLoS Pathogens, Vol 15, Iss 2, p e1007598 (2019)
Resistance to the anthelmintic macrocyclic lactone ivermectin (IVM) has a great impact on the control of parasitic nematodes. The mechanisms by which nematodes adapt to IVM remain to be deciphered. We have identified NHR-8, a nuclear hormone receptor
Externí odkaz:
https://doaj.org/article/e791cfe7730449cf856cd7c88d16d747
Autor:
Andrew C. Kotze, Peter W. Hunt, Philip Skuce, Georg von Samson-Himmelstjerna, Richard J. Martin, Heinz Sager, Jürgen Krücken, Jane Hodgkinson, Anne Lespine, Aaron R. Jex, John S. Gilleard, Robin N. Beech, Adrian J. Wolstenholme, Janina Demeler, Alan P. Robertson, Claude L. Charvet, Cedric Neveu, Ronald Kaminsky, Lucien Rufener, Melanie Alberich, Cecile Menez, Roger K. Prichard
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 4, Iss 3, Pp 164-184 (2014)
Anthelmintic resistance has a great impact on livestock production systems worldwide, is an emerging concern in companion animal medicine, and represents a threat to our ongoing ability to control human soil-transmitted helminths. The Consortium for
Externí odkaz:
https://doaj.org/article/0a884c7c4a7c454ea5b5be5fc9a7abce