Výsledky vyhledávání - "Anne Lesieur-Brooks"

Adenoviral modulation of the tumor-associated system L amino acid transporter, LAT1, alters amino acid transport, cell growth and 4F2/CD98 expressionwith cell-type specific effects in cultured hepatic cells

Autor: Celine Fugere, Anne Lesieur-Brooks, Nancy L. Thompson, Charles A. Vaslet, Bill T. Storey

Publikováno v: International Journal of Cancer. 117:387-397

Altered expression of metabolite transporters is observed frequently in tumor cell lines and primary neoplasms. The extent to which these may to contribute to the growth autonomy associated with cancer is not clear. LAT1 is a major L-type amino acid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9421c2a7d17518292dfe30c48e7b4e0
https://doi.org/10.1002/ijc.21169

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Short-term arginine deprivation results in large-scale modulation of hepatic gene expression in both normal and tumor cells: microarray bioinformatic analysis

Autor: Nancy L. Thompson, Anne Lesieur-Brooks, Bonnie W. Lau, Hwei Xian Leong, Edmond Sabo, Carl P. Simkevich, Celine Fugere

Publikováno v: Nutrition & Metabolism
Nutrition & Metabolism, Vol 3, Iss 1, p 37 (2006)

Background We have reported arginine-sensitive regulation of LAT1 amino acid transporter (SLC 7A5) in normal rodent hepatic cells with loss of arginine sensitivity and high level constitutive expression in tumor cells. We hypothesized that liver cell

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f961223f138d98f3b543f24e158d5b89
https://doi.org/10.1186/1743-7075-3-37

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