Heme uptake across the outer membrane as revealed by crystal structures of the receptor–hemophore complex

Autor: Anne Lecroisey, Kay Diederichs, Stefanie Krieg, Nadia Izadi-Pruneyre, Wolfram Welte, Cécile Wandersman, Philippe Delepelaire, Frédéric Huché

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2009, 106 (4), pp.1045-50. ⟨10.1073/pnas.0809406106⟩
Proceedings of the National Academy of Sciences of the United States of America, 2009, 106 (4), pp.1045-50. ⟨10.1073/pnas.0809406106⟩

Gram-negative bacteria use specific heme uptake systems, relying on outer membrane receptors and excreted heme-binding proteins (hemophores) to scavenge and actively transport heme. To unravel the unknown molecular details involved, we present 3 stru

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82ac815618034d0ab59c3b0cf3798dd2
https://doi.org/10.1073/pnas.0809406106

Haemophore-mediated bacterial haem transport: evidence for a common or overlapping site for haem-free and haem-loaded haemophore on its specific outer membrane receptor

Autor: Philippe Delepelaire, Clarisse Deniau, Sylvie Létoffé, Nicolas Wolff, Emmanuel Dassa, Cécile Wandersman, Anne Lecroisey

Publikováno v: Molecular Microbiology. 41:439-450

Chronic bronchitis is associated with airways obstruction and inflammation. In order to determine whether aerosolized beclomethasone can modulate airway inflammation and diminish airway obstruction, subjects with chronic bronchitis performed spiromet

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9fb5d7b9371ce8b1998d94adb5b2faaa
https://doi.org/10.1046/j.1365-2958.2001.02530.x

Hemophore HasA

Autor: Nadia Izadi-Pruneyre, Nicolas Wolff, Muriel Delepierre, Anne Lecroisey

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91060d75cbfd9a6f69fa5b9344992d20
https://doi.org/10.1002/9781119951438.eibc0690

Purification and characterization of an extracellular 29-kilodalton phospholipase C from Listeria monocytogenes

Autor: Jacques Raveneau, C Geoffroy, Patrick Berche, José A. Vázquez-Boland, J E Alouf, Anne Lecroisey, Jean-Luc Beretti

Publikováno v: Geoffroy, C, Raveneau, J, Beretti, J-L, Lecroisey, A, Vazquez-Boland, J A, Alouf, J E & Berche, P 1991, ' Purification and characterization of an extracellular 29-kilodalton phospholipase C from Listeria monocytogenes ', Infection and Immunity, vol. 59, no. 7, pp. 2382-8 .

We purified and characterized an extracellular phospholipase produced by Listeria monocytogenes. This enzyme was separated as a homogeneous protein of 29 kDa by chromatography on DEAE-52 cellulose and Bio-Gel P100 columns. It is a zinc-dependent phos

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5613e99a2311f6d0c7e6d334aff05c95
https://doi.org/10.1128/iai.59.7.2382-2388.1991

Novel heme ligand displacement by CO in the soluble hemophore HasA and its proximal ligand mutants: implications for heme uptake and release

Autor: Anne Lecroisey, Célia Caillet-Saguy, Kenton R. Rodgers, Gudrun S. Lukat-Rodgers, Nadia Izadi-Pruneyre

Publikováno v: Biochemistry
Biochemistry, American Chemical Society, 2008, 47 (7), pp.2087-98. ⟨10.1021/bi7019518⟩
Biochemistry, 2008, 47 (7), pp.2087-98. ⟨10.1021/bi7019518⟩

International audience; HasASM, a hemophore secreted by the Gram-negative bacteria Serratia marcescens, extracts heme from host hemoproteins and shuttles it to HasRSM, a specific hemophore outer membrane receptor. Heme iron in HasASM is in a six-coor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::041a73a554321517aea19fddd61e25d4
https://hal-pasteur.archives-ouvertes.fr/pasteur-00366684