Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Anne Laure Schang"'
Autor:
Marta Boccazzi, Giulia Macchiarulo, Sophie Lebon, Justyna Janowska, Tifenn Le Charpentier, Valérie Faivre, Jennifer Hua, Davide Marangon, Davide Lecca, Marta Fumagalli, Shyamala Mani, Maria P. Abbracchio, Pierre Gressens, Anne-Laure Schang, Juliette Van Steenwinckel
Publikováno v:
Neurobiology of Disease, Vol 187, Iss , Pp 106315- (2023)
G protein-coupled receptor 17 (GPR17) and the WNT pathway are critical players of oligodendrocyte (OL) differentiation acting as essential timers in developing brain to achieve fully-myelinating cells. However, whether and how these two systems are r
Externí odkaz:
https://doaj.org/article/5762b6f592454653a1582747d57ba39b
Autor:
Anne-Laure Schang, Juliette Van Steenwinckel, Zoi S. Ioannidou, Julia Lipecki, Charlotte Rich-Griffin, Kate Woolley-Allen, Nigel Dyer, Tifenn Le Charpentier, Patrick Schäfer, Bobbi Fleiss, Sascha Ott, Délara Sabéran-Djoneidi, Valérie Mezger, Pierre Gressens
Publikováno v:
Cell Death and Disease, Vol 13, Iss 12, Pp 1-19 (2022)
Abstract Prenatal inflammatory insults accompany prematurity and provoke diffuse white matter injury (DWMI), which is associated with increased risk of neurodevelopmental pathologies, including autism spectrum disorders. DWMI results from maturation
Externí odkaz:
https://doaj.org/article/5d91fa03d0d040c8a238ea7913f823ed
Autor:
Marta Boccazzi, Juliette Van Steenwinckel, Anne-Laure Schang, Valérie Faivre, Tifenn Le Charpentier, Cindy Bokobza, Zsolt Csaba, Claudia Verderio, Marta Fumagalli, Shyamala Mani, Pierre Gressens
Publikováno v:
Cell Death and Disease, Vol 12, Iss 2, Pp 1-12 (2021)
Abstract A leading cause of preterm birth is the exposure to systemic inflammation (maternal/fetal infection), which leads to neuroinflammation and white matter injury (WMI). A wide range of cytokines and chemokines are expressed and upregulated in o
Externí odkaz:
https://doaj.org/article/1ea4c654e3db4b379a06a82c4f236b6b
Autor:
Vanessa Naffaa, Isabelle Hochar, Chéryane Lama, Romain Magny, Anne Regazzetti, Pierre Gressens, Olivier Laprévote, Nicolas Auzeil, Anne-Laure Schang
Publikováno v:
Molecules, Vol 27, Iss 7, p 2274 (2022)
In the central nervous system, the process of myelination involves oligodendrocytes that wrap myelin around axons. Myelin sheaths are mainly composed of lipids and ensure efficient conduction of action potentials. Oligodendrocyte differentiation is a
Externí odkaz:
https://doaj.org/article/fa470ee35c854a739cee01f4f7f3510a
Autor:
Vanessa Naffaa, Romain Magny, Anne Regazzetti, Juliette Van Steenwinckel, Pierre Gressens, Olivier Laprévote, Nicolas Auzeil, Anne-Laure Schang
Publikováno v:
Biochimie. 203:20-31
In the central nervous system, lipids represent approximately 70% of myelin dry weight and play a key role in axon insulation and action potential conduction velocity. Lipids may thus represent sensitive markers of myelin status in physiological and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e59d9d0755183c949ee7fd577f9ad4dd
https://doi.org/10.1016/j.biochi.2022.08.010
https://doi.org/10.1016/j.biochi.2022.08.010
Autor:
Michelle L. Krishnan, Juliette Van Steenwinckel, Anne-Laure Schang, Jun Yan, Johanna Arnadottir, Tifenn Le Charpentier, Zsolt Csaba, Pascal Dournaud, Sara Cipriani, Constance Auvynet, Luigi Titomanlio, Julien Pansiot, Gareth Ball, James P. Boardman, Andrew J. Walley, Alka Saxena, Ghazala Mirza, Bobbi Fleiss, A. David Edwards, Enrico Petretto, Pierre Gressens
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Inflammation mediated by microglia plays a key role in brain injury associated with preterm birth, but little is known about the microglial response in preterm infants. Here, the authors integrate molecular and imaging data from animal models and pre
Externí odkaz:
https://doaj.org/article/68c92e894f6d4f89971dbd07d7ac5142
Autor:
Anouk Benmamar-Badel, Valérie C. Besson, Anne Galland, Sophie Lebon, Bobbi Fleiss, Zsolt Csaba, Leslie Schwendimann, Shyamala Mani, Anne-Laure Schang, Pooja Joshi, Valérie Faivre, Pascal Dournaud, Pierre Gressens, Emmanuelle Bosher, Juliette Van Steenwinckel, Cindy Bokobza, Amélie Montané
Publikováno v:
Annals of neurology. 91(1)
Objectives In the premature newborn, perinatal inflammation mediated by microglia contributes significantly to neurodevelopmental injuries including white matter injury (WMI). Brain inflammation alters development through neuroinflammatory processes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2dbccb84aa1695ae3e63bee9c1c4e1b
https://pubmed.ncbi.nlm.nih.gov/34741343
https://pubmed.ncbi.nlm.nih.gov/34741343
Autor:
Veronique Beneton, Veena Supramaniam, Bobbi Fleiss, Juliette Van Steenwinckel, Ana A. Baburamani, Carina Mallard, Leslie Schwendimann, Jingjun Li, Nathalie Journiac, Pierrette Young-Ten, Boris Matrot, Pierre Gressens, Johanna Maze, A. David Edwards, Claire-Marie Rangon, Sophie Lebon, Henrik Hagberg, Libo Chen, Tingting Fu, Thomas Bourgeois, Tsu Tshen Chuang, Lionel Trottet, Anne-Laure Schang
Publikováno v:
Brain, Behavior, and Immunity
Brain, Behavior, and Immunity, 2018, 74, pp.265-276. ⟨10.1016/j.bbi.2018.09.017⟩
Brain, Behavior, and Immunity, Elsevier, 2018, 74, pp.265-276. ⟨10.1016/j.bbi.2018.09.017⟩
Rangon, C-M, Schang, A-L, Van Steenwinckel, J, Schwendimann, L, Lebon, S, Fu, T, Chen, L, Beneton, V, Journiac, N, Young-Ten, P, Bourgeois, T, Maze, J, Matrot, B, Baburamani, A A, Supramaniam, V, Mallard, C, Trottet, L, Edwards, A D, Hagberg, H, Fleiss, B, Li, J, Tshen Chuang, T & Gressens, P 2018, ' Myelination induction by a histamine H3 receptor antagonist in a mouse model of preterm white matter injury ', Brain, Behavior, and Immunity . https://doi.org/10.1016/j.bbi.2018.09.017
Brain, Behavior, and Immunity, 2018, 74, pp.265-276. ⟨10.1016/j.bbi.2018.09.017⟩
Brain, Behavior, and Immunity, Elsevier, 2018, 74, pp.265-276. ⟨10.1016/j.bbi.2018.09.017⟩
Rangon, C-M, Schang, A-L, Van Steenwinckel, J, Schwendimann, L, Lebon, S, Fu, T, Chen, L, Beneton, V, Journiac, N, Young-Ten, P, Bourgeois, T, Maze, J, Matrot, B, Baburamani, A A, Supramaniam, V, Mallard, C, Trottet, L, Edwards, A D, Hagberg, H, Fleiss, B, Li, J, Tshen Chuang, T & Gressens, P 2018, ' Myelination induction by a histamine H3 receptor antagonist in a mouse model of preterm white matter injury ', Brain, Behavior, and Immunity . https://doi.org/10.1016/j.bbi.2018.09.017
Fifteen million babies are born preterm every year and a significant number suffer from permanent neurological injuries linked to white matter injury (WMI). A chief cause of preterm birth itself and predictor of the severity of WMI is exposure to mat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfa546a18578e42184049bd5d01ae655
https://doi.org/10.1016/j.bbi.2018.09.017
https://doi.org/10.1016/j.bbi.2018.09.017
Autor:
Amélie Montané, Vincent Degos, Rebecca K. Holloway, Valérie C. Besson, Olivier Baud, David H. Rowitch, Pierre Gressens, A. David Edwards, Rahma Hassan-Abdi, Henrik Hagberg, Bobbi Fleiss, Nadia Soussi-Yanicostas, Sophie Lebon, Enrico Petretto, Gareth Ball, Tifenn Le Charpentier, Fabrice Chrétien, Andrée Delahaye-Duriez, Olivier Hennebert, Zsolt Csaba, Paul Aljabar, Anne-Laure Schang, Alka Saxena, Juliette Van Steenwinckel, Veronique E. Miron, Michelle L. Krishnan, Stéphanie Sigaut, Claire Leconte, Franck Verdonk, Cindy Bokobza, Leslie Schwendimann, Walter Birchmeier
Publikováno v:
Brain-A Journal of Neurology
Brain-A Journal of Neurology, Oxford University Press (OUP), 2019, 42 (12), pp.3806-3833. ⟨10.1093/brain/awz319⟩
Brain-A Journal of Neurology, 2019, 42 (12), pp.3806-3833. ⟨10.1093/brain/awz319⟩
Brain-A Journal of Neurology, Oxford University Press (OUP), 2019, 142 (12), pp.3806-3833. ⟨10.1093/brain/awz319⟩
Brain
Brain, Vol. 142, No 12 (2019) pp. 3806-3833
Van Steenwinckel, J, Schang, A-L, Krishnan, M L, Degos, V, Delahaye-Duriez, A, Bokobza, C, Csaba, Z, Verdonk, F, Montané, A, Sigaut, S, Hennebert, O, Lebon, S, Schwendimann, L, Le Charpentier, T, Hassan-Abdi, R, Ball, G, Aljabar, P, Saxena, A, Holloway, R K, Birchmeier, W, Baud, O, Rowitch, D, Miron, V, Chretien, F, Leconte, C, Besson, V C, Petretto, E G, Edwards, A D, Hagberg, H, Soussi-Yanicostas, N, Fleiss, B & Gressens, P 2019, ' Decreased microglial Wnt/β-catenin signalling drives microglial pro-inflammatory activation in the developing brain ', Brain, vol. 142, no. 12, pp. 3806–3833 . https://doi.org/10.1093/brain/awz319
Van Steenwinckel, J, Schang, A-L, Krishnan, M L, Degos, V, Delahaye-Duriez, A, Bokobza, C, Csaba, Z, Verdonk, F, Montané, A, Sigaut, S, Hennebert, O, Lebon, S, Schwendimann, L, Le Charpentier, T, Hassan-Abdi, R, Ball, G, Aljabar, P, Saxena, A, Holloway, R K, Birchmeier, W, Baud, O, Rowitch, D, Miron, V, Chretien, F, Leconte, C, Besson, V C, Petretto, E G, Edwards, A D, Hagberg, H, Soussi-Yanicostas, N, Fleiss, B & Gressens, P 2019, ' Decreased microglial Wnt/β-catenin signalling drives microglial pro-inflammatory activation in the developing brain ', Brain : a journal of neurology, vol. 142, no. 12, pp. 3806–3833 . https://doi.org/10.1093/brain/awz319
Brain-A Journal of Neurology, Oxford University Press (OUP), 2019, 42 (12), pp.3806-3833. ⟨10.1093/brain/awz319⟩
Brain-A Journal of Neurology, 2019, 42 (12), pp.3806-3833. ⟨10.1093/brain/awz319⟩
Brain-A Journal of Neurology, Oxford University Press (OUP), 2019, 142 (12), pp.3806-3833. ⟨10.1093/brain/awz319⟩
Brain
Brain, Vol. 142, No 12 (2019) pp. 3806-3833
Van Steenwinckel, J, Schang, A-L, Krishnan, M L, Degos, V, Delahaye-Duriez, A, Bokobza, C, Csaba, Z, Verdonk, F, Montané, A, Sigaut, S, Hennebert, O, Lebon, S, Schwendimann, L, Le Charpentier, T, Hassan-Abdi, R, Ball, G, Aljabar, P, Saxena, A, Holloway, R K, Birchmeier, W, Baud, O, Rowitch, D, Miron, V, Chretien, F, Leconte, C, Besson, V C, Petretto, E G, Edwards, A D, Hagberg, H, Soussi-Yanicostas, N, Fleiss, B & Gressens, P 2019, ' Decreased microglial Wnt/β-catenin signalling drives microglial pro-inflammatory activation in the developing brain ', Brain, vol. 142, no. 12, pp. 3806–3833 . https://doi.org/10.1093/brain/awz319
Van Steenwinckel, J, Schang, A-L, Krishnan, M L, Degos, V, Delahaye-Duriez, A, Bokobza, C, Csaba, Z, Verdonk, F, Montané, A, Sigaut, S, Hennebert, O, Lebon, S, Schwendimann, L, Le Charpentier, T, Hassan-Abdi, R, Ball, G, Aljabar, P, Saxena, A, Holloway, R K, Birchmeier, W, Baud, O, Rowitch, D, Miron, V, Chretien, F, Leconte, C, Besson, V C, Petretto, E G, Edwards, A D, Hagberg, H, Soussi-Yanicostas, N, Fleiss, B & Gressens, P 2019, ' Decreased microglial Wnt/β-catenin signalling drives microglial pro-inflammatory activation in the developing brain ', Brain : a journal of neurology, vol. 142, no. 12, pp. 3806–3833 . https://doi.org/10.1093/brain/awz319
International audience; Microglia of the developing brain have unique functional properties but how their activation states are regulated is poorly understood. Inflammatory activation of microglia in the still-developing brain of preterm-born infants
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d5010c4ea37526701c318b122a40130
https://www.repository.cam.ac.uk/handle/1810/301606
https://www.repository.cam.ac.uk/handle/1810/301606
Publikováno v:
Clinical Genetics. 93:467-480
Patients suffering from psychiatric disorders have a life span burden, which represents an enormous human, family, social, and economical cost. Several concepts have revolutionized our way of appraising neuropsychiatric disorders (NPDs). They result
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd5449bf240d0f792a50f5310a172a92
https://doi.org/10.1111/cge.13097
https://doi.org/10.1111/cge.13097