Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Anne Laure Goenaga"'
Autor:
James D. Marks, Ulrik B. Nielsen, Birgit Schoeberl, Gregory P. Adams, Fraser Conrad, Jianlong Lou, Hao Zou, Brian D. Harms, Anne-Laure Goenaga, Yu Zhou
PDF file, 450KB, Biphasic distribution of the increase in binding affinity for conversion from monovalent to bivalent forms for antibodies with different intrinsic affinities.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dad4b36218fddcc93214aa8599e29c9
https://doi.org/10.1158/1535-7163.22498900.v1
https://doi.org/10.1158/1535-7163.22498900.v1
Autor:
James D. Marks, Ulrik B. Nielsen, Birgit Schoeberl, Gregory P. Adams, Fraser Conrad, Jianlong Lou, Hao Zou, Brian D. Harms, Anne-Laure Goenaga, Yu Zhou
PDF file, 95KB, Comparison of cell-binding curves for low and high affinity anti-EGFR IgG antibodies at the experimental incubation time and a hypothetical time.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d912714f35509e5cb38fad73680d2e5
https://doi.org/10.1158/1535-7163.22498897
https://doi.org/10.1158/1535-7163.22498897
Autor:
James D. Marks, Ulrik B. Nielsen, Birgit Schoeberl, Gregory P. Adams, Fraser Conrad, Jianlong Lou, Hao Zou, Brian D. Harms, Anne-Laure Goenaga, Yu Zhou
PDF file, 52KB, Comparison of measured apparent IgG affinities vs affinities calculated by using a mathematical model on cells of different EGFR density (A431, MDAMB468, and MDAMB231).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80173de6710a95bc7f5e6126c03912b9
https://doi.org/10.1158/1535-7163.22498879.v1
https://doi.org/10.1158/1535-7163.22498879.v1
Autor:
James D. Marks, Ulrik B. Nielsen, Birgit Schoeberl, Gregory P. Adams, Fraser Conrad, Jianlong Lou, Hao Zou, Brian D. Harms, Anne-Laure Goenaga, Yu Zhou
PDF file, 56KB, Kinetic parameters used in the computational model of antibody binding.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01eaae82ca847d4d1067a9547389809e
https://doi.org/10.1158/1535-7163.22498882
https://doi.org/10.1158/1535-7163.22498882
Autor:
James D. Marks, Ulrik B. Nielsen, Birgit Schoeberl, Gregory P. Adams, Fraser Conrad, Jianlong Lou, Hao Zou, Brian D. Harms, Anne-Laure Goenaga, Yu Zhou
PDF file, 62KB.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2c14f673a9ec3ffd164c3530441ffc2
https://doi.org/10.1158/1535-7163.22498894.v1
https://doi.org/10.1158/1535-7163.22498894.v1
Autor:
Anne-Laure Goenaga, I-Ming Wang, Bryan S. Clay, Susanne Lang, Annabel Wang, Peter Weady, Smitha P.S. Pillai, Sripad Ram, Leah Mitchell, Michael Eisenbraun, Joseph Binder, Liliana Maruri Avidal, David Kirn, Robert Hollingsworth, Clare Lees
Publikováno v:
Cancer Research. 82:5617-5617
Oncolytic viruses (OVs) have been widely investigated as cancer immunotherapy platforms and are represented by a diverse group of DNA and RNA viruses. We are currently investigating a genetically modified oncolytic vaccinia virus as a best-in-class t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c2d6e23c91f128dc401ee00f2b3d33f7
https://doi.org/10.1158/1538-7445.am2022-5617
https://doi.org/10.1158/1538-7445.am2022-5617
Autor:
Bruce A. Green, Richard J. Anderson, Derek John Falconer, Neil C. Sheppard, Shawn R. Makinen, Anne-Laure Goenaga, Stephen J. Gracheck, Jim E. Eyles, James R. Merson, Risini D. Weeratna, Susanne Lang, Siradanahalli Guru, Bingsheng Chang
Publikováno v:
Vaccine. 34(50)
We evaluated 52 different E. coli expressed pneumococcal proteins as immunogens in a BALB/c mouse model of S. pneumoniae lung infection. Proteins were selected based on genetic conservation across disease-causing serotypes and bioinformatic predictio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e0e1d47c7a0000dc87f3533c4098fdd
https://pubmed.ncbi.nlm.nih.gov/27816374
https://pubmed.ncbi.nlm.nih.gov/27816374
Autor:
Hao Zou, Ulrik B. Nielsen, Fraser Conrad, Yu Zhou, Brian Harms, Anne Laure Goenaga, Gregory P. Adams, Jianlong Lou, James D. Marks, Birgit Schoeberl
Publikováno v:
Molecular cancer therapeutics. 11(7)
Aberrant expression and activation of EGF receptor (EGFR) has been implicated in the development and progression of many human cancers. As such, targeted therapeutic inhibition of EGFR, for example by antibodies, is a promising anticancer strategy. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38e22eaee6d9ab946019c09cf4f9a6f8
https://pubmed.ncbi.nlm.nih.gov/22564724
https://pubmed.ncbi.nlm.nih.gov/22564724
Autor:
Lan Huang, Marie-Alix Poul, Christian Auclair, Dmitri B. Kirpotin, James D. Marks, Bin Liu, Anne-Laure Goenaga, Daryl C. Drummond, Christine Legay, Yu Zhou, Houcine Bougherara
Publikováno v:
Molecular immunology. 44(15)
To generate a panel of antibodies binding human breast cancers, a human single chain Fv phage display library was selected for rapid internalization into the SK-BR-3 breast cancer cell line. Thirteen unique antibodies were identified within the 55 ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4112ee52cb6c9f65033880023dceea6
https://pubmed.ncbi.nlm.nih.gov/17498801
https://pubmed.ncbi.nlm.nih.gov/17498801