Zobrazeno 1 - 10 of 12 pro vyhledávání: '"Anne Laure Chanson"'
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Association between High Levels of Blood Macrophage Migration Inhibitory Factor, Inappropriate Adrenal Response, and Early Death in Patients with Severe Sepsis
Autor: Thierry Calandra, Marieke Emonts, Peter W. M. Hermans, Fred C.G.J. Sweep, Nicolai Grebenchtchikov, Veronique Erard, Anne Laure Chanson, Jan A. Hazelzet, Pascal Renner, Marlies Knaup, Anneke Geurts-Moespot
Publikováno v: Clinical Infectious Diseases, 44, 1321-1328. Oxford University Press
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Clinical Infectious Diseases, 44, 1321-8
Clinical Infectious Diseases, 44, 10, pp. 1321-8
Clinical Infectious Diseases, vol. 44, no. 10, pp. 1321-1328
Contains fulltext : 52472.pdf (Publisher’s version ) (Closed access) BACKGROUND: Identification of new therapeutic targets remains an imperative goal to improve the morbidity and mortality associated with severe sepsis and septic shock. Macrophage
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5292c2e9ebeb67497f73683e792313f5
http://doc.rero.ch/record/295638/files/44-10-1321.pdf
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2
Macrophage Migration Inhibitory Factor Deficiency Is Associated With Impaired Killing of Gram-Negative Bacteria by Macrophages and Increased Susceptibility to Klebsiella pneumoniae Sepsis
Autor: Anne-Laure Chanson, Thierry Calandra, Julie Delaloye, Didier Le Roy, Marlyse Giddey, Thierry Roger
Publikováno v: JOURNAL OF INFECTIOUS DISEASES
Journal of Infectious Diseases, vol. 207, no. 2, pp. 331-339
The Journal of infectious diseases
The cytokine macrophage migration inhibitory factor (MIF) is an important component of the early proinflammatory response of the innate immune system. However, the antimicrobial defense mechanisms mediated by MIF remain fairly mysterious. In the pres
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d7e0594b5ee14e080277ec8085d26db
https://doi.org/10.1093/infdis/jis673
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3
A functional microsatellite of the macrophage migration inhibitory factor gene associated with meningococcal disease
Autor: Michael Levin, Marcel van Deuren, Fred C.G.J. Sweep, Elene Haralambous, Helen Betts, Murielle Bochud, Veronique Erard, Tom Sprong, Robert C. Read, Elliott Mermel, Thierry Roger, Pascal Renner, Thierry Calandra, Saul N. Faust, Pierre-Yves Bochud, Anne-Laure Chanson, Marlies Knaup Reymond
Publikováno v: FASEB journal : official publication of the Federation of American Societies for Experimental Biolog
FASEB JOURNAL
The Faseb Journal, 26, 907-16
The Faseb Journal, 26, 2, pp. 907-16
The FASEB journal : official publication of the Federation of American Societies for Experimental Bi
Macrophage migration inhibitory factor (MIF) is an abundantly expressed proinflammatory cytokine playing a critical role in innate immunity and sepsis and other inflammatory diseases. We examined whether functional MIF gene polymorphisms ( 794 CATT(5
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4
Histone deacetylase inhibitors impair innate immune responses to Toll-like receptor agonists and to infection
Autor: Didier Le Roy, Xavier C. Ding, Anne-Laure Chanson, Geneviève Goy, Jacques Schrenzel, Jérôme Lugrin, Thibaud Koessler, Thierry Roger, Thierry Calandra, Marlies Knaup Reymond, Matteo Mombelli, Patrice Francois, Isabelle Miconnet
Publikováno v: Blood, Vol. 117, No 4 (2011) pp. 1205-17
BLOOD
Blood
Regulated by histone acetyltransferases and deacetylases (HDACs), histone acetylation is a key epigenetic mechanism controlling chromatin structure, DNA accessibility, and gene expression. HDAC inhibitors induce growth arrest, differentiation, and ap
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::519a82183d32070b1234ffe5e605a1d9
https://doi.org/10.1182/blood-2010-05-284711
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5
Histone deacetylase inhibitors repress macrophage migration inhibitory factor (MIF) expression by targeting MIF gene transcription through a local chromatin deacetylation
Autor: Anne-Laure Chanson, Thierry Calandra, Jérôme Lugrin, Thierry Roger, Fred C.G.J. Sweep, Xavier C. Ding, Didier Le Roy
Publikováno v: Biochimica et Biophysica Acta. Molecular Cell Research, 1793, 1749-58
Biochimica et biophysica acta
Biochimica et Biophysica Acta. Molecular Cell Research, 1793, 11, pp. 1749-58
Contains fulltext : 80470.pdf (Publisher’s version ) (Closed access) The cytokine macrophage migration inhibitory factor plays a central role in inflammation, cell proliferation and tumorigenesis. Moreover, macrophage migration inhibitory factor le
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0570501b636ee802db2e33dead87ab0
https://doi.org/10.1016/j.bbamcr.2009.09.007
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6
Protection from lethal gram-negative bacterial sepsis by targeting Toll-like receptor 4
Autor: Thierry Calandra, Didier Le Roy, Shizuo Akira, Davide Mauri, Anne-Laure Chanson, Kim Burns, Thierry Roger, Beat M. Riederer, Céline Froidevaux, Marlies Knaup Reymond
Publikováno v: Proceedings of the National Academy of Sciences of the United States of America
Toll-like receptor 4 (TLR4), the signal-transducing molecule of the LPS receptor complex, plays a fundamental role in the sensing of LPS from Gram-negative bacteria. Activation of TLR4 signaling pathways by LPS is a critical upstream event in the pat
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7
Macrophage migration inhibitory factor promotes innate immune responses by suppressing glucocorticoid-induced expression of mitogen-activated protein kinase phosphatase-1
Autor: Marlies Knaup-Reymond, Anne Laure Chanson, Thierry Roger, Thierry Calandra
Publikováno v: European Journal of Immunology. 35:3405-3413
The pro-inflammatory cytokine macrophage migration inhibitory factor (MIF) acts as a physiological counter-regulator of the immuno-suppressive effects of glucocorticoids. However, the mechanisms whereby MIF exerts its counter-balancing effect remain
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38badd94629edcc7c92876f4d790a77c
https://doi.org/10.1002/eji.200535413
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8
Regulation of constitutive and microbial pathogen-induced human macrophage migration inhibitory factor (MIF) gene expression
Autor: Pascal Renner, Xavier C. Ding, Anne-Laure Chanson, Thierry Roger, Thierry Calandra
Publikováno v: European journal of immunology
The cytokine macrophage migration inhibitory factor (MIF) is an important regulator of innate immunity, inflammation and oncogenesis. However, four decades after its identification, the molecular mechanism(s) regulating the expression of the MIF gene
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49be6921ad8396c8febe7a86732095f9
https://pubmed.ncbi.nlm.nih.gov/18034423
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10
Histone deacetylase inhibitors impair antibacterial defenses of macrophages
Autor: Ivana Rubino, Thierry Calandra, Anne-Laure Chanson, Marlyse Giddey, Thierry Roger, Matteo Mombelli, Jérôme Lugrin
Publikováno v: The Journal of infectious diseases
Journal of Infectious Diseases, vol. 204, no. 9, pp. 1367-1374
Histone deacetylases (HDACs) control gene expression by deacetylating histones and nonhistone proteins. HDAC inhibitors (HDACi) are powerful anticancer drugs that exert anti-inflammatory and immunomodulatory activities. We recently reported a proof-o
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