Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Anne L. Prieto"'
Autor:
Anne L. Prieto, Cary Lai
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 6, p 3369 (2024)
The TAMs are a subfamily of receptor tyrosine kinases (RTKs) comprised of three members, Tyro3, Axl and Mer. Evidence in support of the existence of this subfamily emerged from a screen for novel RTKs performed in the laboratory of Dr. Greg Lemke in
Externí odkaz:
https://doaj.org/article/827b82b407514de08b4f38558b19037a
Publikováno v:
Molecular Neurobiology. 57:3568-3588
The neuregulins (Nrgs 1–4) are a family of signaling molecules that play diverse roles in the nervous system. Nrg1 has been implicated in the formation of synapses and in synaptic plasticity. Previous studies have shown Nrg1 can affect neurite outg
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e36800 (2012)
The dysregulation of receptor protein tyrosine kinase (RPTK) function can result in changes in cell proliferation, cell growth and metastasis leading to malignant transformation. Among RPTKs, the TAM receptor family composed of three members Tyro3, A
Externí odkaz:
https://doaj.org/article/edfebea9679045d68f22aa9bd6ed4ce8
Publikováno v:
The Journal of comparative neurology. 527(4)
Neuregulin-3 (Nrg3) is a member of the Nrg family of growth factors identified as risk factors for schizophrenia. There are three Nrgs expressed in the nervous system (Nrg1-3) and of these Nrg1 has been the best characterized. To set the groundwork f
Autor:
Jan Anker Jahnsen, Michael R. Vasko, Eivind Vefring, Sumner Burstein, Benjamin F. Cravatt, David K. O’Dell, Douglas McHugh, Eric L. Thompson, Kim Masuda, H. Velocity Hughes, Neta Rimmerman, Jay Shih Chieh Chen, Sherry Shu Jung Hu, Heather B. Bradshaw, Anne L. Prieto, J. Michael Walker
Publikováno v:
Molecular Pharmacology. 74:213-224
N-arachidonoyl glycine is an endogenous arachidonoyl amide that activates the orphan G protein-coupled receptor (GPCR) GPR18 in a pertussis toxin (PTX)-sensitive manner and produces antinociceptive and antiinflammatory effects. It is produced by dire
Autor:
Donna L. Gruol, Lely A. Quina, C. L. Ur, Vi Nguyen, Penney Blakely-Gonzales, Jeffrey G. Netzeband, Shannon M. Conroy, Anne L. Prieto
Publikováno v:
Journal of Neuroimmunology. 155:43-54
CNS levels of the cytokine interleukin-6 (IL-6) are elevated during CNS injury and disease, but it is unclear if IL-6 contributes to the pathologic process. Our studies show that in a well-characterized CNS developmental model system, primary culture
Publikováno v:
Experimental Eye Research. 75:391-400
The phagocytosis of photoreceptor outer segments by retinal pigment epithelial (RPE) cells plays a critical role in preserving normal retinal function. Recently the receptor protein tyrosine kinase (RTK) Mer, has been shown to be necessary for this c
Autor:
Todd M. Mowery, Jennifer B. Buchholz, Anne L. Prieto, Sarah M. Wilson, Blair Dina, Polina V. Kostylev, Preston E. Garraghty
Publikováno v:
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 40
Autism spectrum disorders (ASD) is diagnosed in males at a much higher rate than females. For this reason, the majority of autism research has used male subjects exclusively. However; more recent studies using genetic sex as a factor find that the de
Autor:
Martin S. Obin, Barry L. Burgess, Michael O. Hall, Anne L. Prieto, Mary J. Heeb, Brian J. Agnew, Toshka A. Abrams
Publikováno v:
Experimental Eye Research. 73:509-520
The function and viability of vertebrate photoreceptors requires the daily phagocytosis of photoreceptor outer segments (OS) by the adjacent retinal pigment epithelium (RPE). We demonstrate here a critical role in this process for Gas6 and by implica
Publikováno v:
The Journal of Comparative Neurology. 425:295-314
Tyro-3, Axl, and Mer are three related receptor protein-tyrosine kinases (RPTKs) characterized by an extracellular domain exhibiting significant amino acid sequence similarity to neural cell adhesion molecules. The molecule Gas6 (for growth arrest-sp