Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Anne L. Morkbak"'
Publikováno v:
Haematologica, Vol 92, Iss 12 (2007)
We confirm a decrease in cobalamins during pregnancy, and report that the active part of cobalamins (holotranscobalamin, holoTC) remains unchanged. The decrease in cobalamins is explained by a decreased holohaptocorrin (holoHC), suggesting that holoT
Externí odkaz:
https://doaj.org/article/fef314ab88b446d2847b1e2234b03c36
Autor:
Katrine Hygum, Dorte L Lildballe, Eva H Greibe, Anne L Morkbak, Steen S Poulsen, Boe S Sorensen, Torben E Petersen, Ebba Nexo
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e20638 (2011)
In humans, the cobalamin (Cbl) -binding protein transcobalamin (TC) transports Cbl from the intestine and into all the cells of the body, whereas the glycoprotein haptocorrin (HC), which is present in both blood and exocrine secretions, is able to bi
Externí odkaz:
https://doaj.org/article/9bbaddec7bbf48a2a4f4052f0a8a0582
Publikováno v:
Hardlei, T F, Mørkbak, A L & Nexo, E 2007, ' Enzymatic extraction of cobalamin from monoclonal antibody captured haptocorrin and transcobalamin. ', Clinical Biochemistry, vol. 40, no. 18, pp. 1392-7 . https://doi.org/10.1016/j.clinbiochem.2007.09.008
Objectives: Current extraction methods for cobalamins from serum influence the molecular characteristics of the vitamin. Therefore, an extraction procedure that leaves the cobalamins unchanged is needed. Design and methods: Monoclonal antibodies towa
Autor:
Anne-Mette Hvas, Anne L. Morkbak, Eva Greibe, Dorte L Lildballe, Ebba Nexo, Birgitte Horst Andreasen
Publikováno v:
Greibe, E, Andreasen, B H, Lildballe, D L, Morkbak, A L, Hvas, A-M & Nexø, E 2011, ' Uptake of cobalamin and markers of cobalamin status: a longitudinal study of healthy pregnant women ', Clinical Chemistry and Laboratory Medicine, vol. 49 . https://doi.org/10.1515/CCLM.2011.682
BACKGROUND Currently, it is unknown whether the decline in plasma cobalamin observed during pregnancy is caused by malabsorption of the vitamin. This study examined cobalamin absorption and markers of cobalamin status during normal pregnancy. METHODS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da1fc04fa23c18e126662fd1b8b01ed2
https://pure.au.dk/portal/da/publications/uptake-of-cobalamin-and-markers-of-cobalamin-status-a-longitudinal-study-of-healthy-pregnant-women(b7d7613d-48a1-4136-b90a-13095fc077e2).html
https://pure.au.dk/portal/da/publications/uptake-of-cobalamin-and-markers-of-cobalamin-status-a-longitudinal-study-of-healthy-pregnant-women(b7d7613d-48a1-4136-b90a-13095fc077e2).html
Autor:
Boe Sandahl Sorensen, Ebba Nexo, Katrine Hygum, Anne L. Morkbak, Dorte L Lildballe, Steen Seier Poulsen, Eva Greibe, Torben E. Petersen
Publikováno v:
Hygum, K, Lildballe, D L, Greibe, E H, Morkbak, A L, Poulsen, S S, Sørensen, B S, Petersen, T E & Nexø, E 2011, ' Mouse Transcobalamin Has Features Resembling both Human Transcobalamin and Haptocorrin ', P L o S One, vol. 6, no. 5, pp. e20638 . https://doi.org/10.1371/journal.pone.0020638
PLoS ONE
PLoS ONE, Vol 6, Iss 5, p e20638 (2011)
PLoS ONE
PLoS ONE, Vol 6, Iss 5, p e20638 (2011)
In humans, the cobalamin (Cbl) -binding protein transcobalamin (TC) transports Cbl from the intestine and into all the cells of the body, whereas the glycoprotein haptocorrin (HC), which is present in both blood and exocrine secretions, is able to bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::065a159519f64a1d440a9adb249e4ea5
https://pure.au.dk/ws/files/48531203/journal.pone.0020638.pdf
https://pure.au.dk/ws/files/48531203/journal.pone.0020638.pdf
Publikováno v:
Hvas, A-M, Morkbak, A L, Hardlei, T F & Nexø, E 2011, ' The vitamin B12 absorption test, CobaSorb, identifies patients not requiring vitamin B12 injection therapy ', Scandinavian Journal of Clinical & Laboratory Investigation, vol. 71, no. 5, pp. 432-8 . https://doi.org/10.3109/00365513.2011.581389
Background. Treatment with vitamin B12 has virtually no side effects; however, life-long treatment is inconvenient for the patient and constitutes a cost for society. Objective. To investigate whether vitamin B12 injection treatment reflects the actu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7654f37df4abcf16a40c9916df2e183
https://pure.au.dk/portal/da/publications/the-vitamin-b12-absorption-test-cobasorb-identifies-patients-not-requiring-vitamin-b12-injection-therapy(781d09b1-9c58-4c78-bd01-bb07355aec8e).html
https://pure.au.dk/portal/da/publications/the-vitamin-b12-absorption-test-cobasorb-identifies-patients-not-requiring-vitamin-b12-injection-therapy(781d09b1-9c58-4c78-bd01-bb07355aec8e).html
Autor:
Tore Forsingdal Hardlei, Anne-Mette Hvas, Mustafa Vakur Bor, Ebba Nexo, Lynn B. Bailey, Anne L. Morkbak
Publikováno v:
Hardlei, T F, Mørkbak, A L, Bor, M V, Bailey, L B, Hvas, A-M & Nexø, E 2009, ' Assessment of Vitamin B12 Absorption Based on the Accumulation of Orally Administered Cyanocobalamin on Transcobalamin ', Clinical Chemistry . https://doi.org/10.1373/clinchem.2009.131524
Hardlei, T F, Mørkbak, A L, Bor, M V, Bailey, L B, Hvas, A-M & Nexo, E 2010, ' Assessment of vitamin B(12) absorption based on the accumulation of orally administered cyanocobalamin on transcobalamin ', Clinical Chemistry, vol. 56, no. 3, pp. 432-6 . https://doi.org/10.1373/clinchem.2009.131524
Hardlei, T F, Mørkbak, A L, Bor, M V, Bailey, L B, Hvas, A-M & Nexo, E 2010, ' Assessment of vitamin B(12) absorption based on the accumulation of orally administered cyanocobalamin on transcobalamin ', Clinical Chemistry, vol. 56, no. 3, pp. 432-6 . https://doi.org/10.1373/clinchem.2009.131524
Background: Vitamin B12, or cobalamin (Cbl), is absorbed in the intestine and transported to the cells bound to transcobalamin (TC). We hypothesize that cyanocobalamin (CNCbl) is absorbed unchanged, thereby allowing measurement of the complex of CNCb
Publikováno v:
Mørkbak, A L, Nexo, E & Poulsen, S S 2007, ' Haptocorrin in humans. ', Clinical Chemistry and Laboratory Medicine, vol. 45, no. 12, pp. 1751-9 . https://doi.org/10.1515/CCLM.2007.343
Background: Evolutionary haptocorrin is the youngest of the cobalamin-binding proteins. It evolved by duplication of the intrinsic factor gene and has been identified in most mammals examined. Its ability to bind both cobalamin and analogues is well
Publikováno v:
Larsen, K L, Andersen, S B, Mørkbak, A L & Wimmer, R 2007, ' Inclusion Complexes of Fusidic Acid and Three Structurally Related Compounds with Cyclodextrins ', Journal of Inclusion Phenomena and Macrocyclic Chemistry, vol. 57, no. 1-4, pp. 185-190 . https://doi.org/10.1007/s10847-006-9198-7
Larsen, K L, Bruse Andersen, S, Mørkbak, A L & Wimmer, R 2006, ' Inclusion complexes of fusidic acid and three structurally related compounds with cyclodextrins ', 13th International Cyclodextrin Symposium, Torino, Italy, 14/05/2006-17/05/2006 .
Aalborg University
Larsen, K L, Bruse Andersen, S, Mørkbak, A L & Wimmer, R 2006, ' Inclusion complexes of fusidic acid and three structurally related compounds with cyclodextrins ', 13th International Cyclodextrin Symposium, Torino, Italy, 14/05/2006-17/05/2006 .
Aalborg University
The inclusion complexes between fusidate, 3-keto fusidate, 11-keto fusidate and 11-deoxy fusidate and α-, β-, and γ-cyclodextrin (CD) were studied using capillary electrophoresis. By monitoring the changes in mobility of the negatively charged com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70a377e354e17266349e5ea0a01b953c
https://vbn.aau.dk/da/publications/0ce8bb60-a8b8-11dc-8d1d-000ea68e967b
https://vbn.aau.dk/da/publications/0ce8bb60-a8b8-11dc-8d1d-000ea68e967b
Publikováno v:
Clinica chimica acta; international journal of clinical chemistry. 376(1-2)
A recently developed non-radioactive vitamin B(12) absorption test (CobaSorb) was further explored to identify the best marker for reflection of vitamin B(12) absorption and to determine the duration of the test.Seventy-eight healthy individuals (age