Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Anne L. Maerz"'
Autor:
Heidi E Drummer, Melissa K Hill, Anne L Maerz, Stephanie Wood, Paul A Ramsland, Johnson Mak, Pantelis Poumbourios
Publikováno v:
PLoS Pathogens, Vol 9, Iss 4, p e1003218 (2013)
The HIV-1 gp120-gp41 complex, which mediates viral fusion and cellular entry, undergoes rapid evolution within its external glycan shield to enable escape from neutralizing antibody (NAb). Understanding how conserved protein determinants retain funct
Externí odkaz:
https://doaj.org/article/4613c3f8b4ef4162ac4fa6e12f557b61
Publikováno v:
Journal of Virology. 80:7844-7853
The hepatitis C virus (HCV) glycoproteins E1 and E2 form a heterodimer that mediates CD81 receptor binding and viral entry. In this study, we used site-directed mutagenesis to examine the functional role of a conserved G 436 WLAGLFY motif of E2. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf8f19c0249275581154ff0e423efe0e
https://doi.org/10.1128/jvi.00029-06
https://doi.org/10.1128/jvi.00029-06
Autor:
Suzanne M. Crowe, Anne L. Maerz, Hiu Tat Chan, Katherine Kedzierska, Anthony Jaworowski, Angel F. Lopez, Secondo Sonza, Johnson Mak, Tammra Warby
Publikováno v:
AIDS. 14:1739-1748
Background Previous studies of the effect of granulocyte-macrophage colony-stimulating factor (GM-CSF) on HIV-1 replication in macrophages have had inconsistent results, variously reporting no effect, augmentation or inhibition of viral replication.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c9e568b0d8ef4b91973905f8c9ab315
https://doi.org/10.1097/00002030-200008180-00008
https://doi.org/10.1097/00002030-200008180-00008
Autor:
Kate Silburn, Wayne Gerrard Reilly, Michael K. Manthey, Pantelis Poumbourios, Dale A. McPhee, Anne L. Maerz, Robert George Whittaker, Cyril C. Curtain, Alan Kirkpatrick
Publikováno v:
AIDS Research and Human Retroviruses. 14:385-392
Contrary to earlier reports, we have found that tri- and hexapeptides analogous or homologous with segments of the 23-residue N-terminal fusion sequence (FS) of the viral transmembrane glycoprotein gp41 (residues 517-539) did not significantly inhibi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ff5068a845be5eed1fa1a1ae4ab4d9f
https://doi.org/10.1089/aid.1998.14.385
https://doi.org/10.1089/aid.1998.14.385
Autor:
Suzanne M. Crowe, Nicholas J. Vardaxis, Marilyn J. Hewish, Stephen J. Kent, Anne L. Maerz, Michael S. McGrath, John Mills
Publikováno v:
Journal of Leukocyte Biology. 56:318-327
HIV-1 infection of peripheral blood monocyte-derived macrophages (MDMs) is unrelated to the level of CD4 expression on the surface of the cell, is associated with considerable donor variability, causes minimal cytopathology, and results in peak viral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da4dd022254bcb55b6f39c02ad89c88e
https://doi.org/10.1002/jlb.56.3.318
https://doi.org/10.1002/jlb.56.3.318
Autor:
Séverine Baär, Anna Kathryn Bellamy-McIntyre, Chan-Sien Lay, Pantelis Poumbourios, Anne L. Maerz, Gert H Talbo, Heidi E. Drummer
Publikováno v:
The Journal of biological chemistry. 282(32)
The binding of CD4 and chemokine receptors to the gp120 attachment glycoprotein of human immunodeficiency virus triggers refolding of the associated gp41 fusion glycoprotein into a trimer of hairpins with a 6-helix bundle (6HB) core. These events lea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40b00da4bbc373cfc2a2270fcf1e1441
https://pubmed.ncbi.nlm.nih.gov/17526486
https://pubmed.ncbi.nlm.nih.gov/17526486
Retroviral transmembrane proteins (TMs) contain an N-terminal fusion peptide that initiates virus-cell membrane fusion. The fusion peptide is linked to the coiled-coil core through a conserved sequence that is often rich in glycines. We investigated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f18f834f461836231add5ae6e5810ae
https://europepmc.org/articles/PMC1061562/
https://europepmc.org/articles/PMC1061562/
Publikováno v:
The Journal of biological chemistry. 278(43)
Protein-protein interaction surfaces can exhibit structural plasticity, a mechanism whereby an interface adapts to mutations as binding partners coevolve. The HIV-1 envelope glycoprotein gp120-gp41 complex, which is responsible for receptor attachmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dac1dbaea5bc6098ffda5b2274e99cc9
https://pubmed.ncbi.nlm.nih.gov/12923196
https://pubmed.ncbi.nlm.nih.gov/12923196
Publikováno v:
FEBS letters. 546(2-3)
Hepatitis C virus (HCV) glycoproteins E1 and E2 are believed to be retained in the endoplasmic reticulum (ER) or cis-Golgi compartment via retention signals located in their transmembrane domains. Here we describe the detection of E1 and E2 at the su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26a77b72a41578f6db00d6471d64addc
https://pubmed.ncbi.nlm.nih.gov/12832074
https://pubmed.ncbi.nlm.nih.gov/12832074
Publikováno v:
The Journal of biological chemistry. 276(52)
To investigate the structural context of the fusion peptide region in human T-cell leukemia virus type 1 gp21, maltose-binding protein (MBP) was used as an N-terminal solubilization partner for the entire gp21 ectodomain (residues 313-445) and C-term
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c529b1fcd345da238313b363eb54a77
https://pubmed.ncbi.nlm.nih.gov/11595747
https://pubmed.ncbi.nlm.nih.gov/11595747