Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Anne Korwitz"'
Autor:
Carsten Merkwirth, Paola Martinelli, Anne Korwitz, Michela Morbin, Hella S Brönneke, Sabine D Jordan, Elena I Rugarli, Thomas Langer
Publikováno v:
PLoS Genetics, Vol 8, Iss 11, p e1003021 (2012)
Fusion and fission of mitochondria maintain the functional integrity of mitochondria and protect against neurodegeneration, but how mitochondrial dysfunctions trigger neuronal loss remains ill-defined. Prohibitins form large ring complexes in the inn
Externí odkaz:
https://doaj.org/article/5db45e9d209245a78fd19f8f0e725ed6
Autor:
Anne Korwitz-Reichelt, Claudia Till, Kathleen Grundke, Despina Tsortouktzidis, Jörn Oliver Sass
Publikováno v:
Metabolic brain disease. 34(6)
Acylpeptide hydrolase (APEH) is a serine protease involved in the recycling of amino acids from acylated peptides. Beyond that, APEH participates in the metabolism of the antiepileptic drug valproic acid (2-propylpentanoic acid; VPA) by catalyzing th
Autor:
Elena I. Rugarli, Simon E. Tröder, Hans-Georg Sprenger, Carsten Merkwirth, Ricarda Richter-Dennerlein, Anne Korwitz, Pedro M. Quirós, Thomas Langer, Carlos López-Otín
Publikováno v:
The Journal of Cell Biology
J Cell Biol
J Cell Biol
Loss of OMA1 in a mouse model of neurodegeneration stabilizes fusion-active L-OPA1, which supports neuronal survival by preventing apoptosis, independent of its effects on cristae morphogenesis.
Proteolytic cleavage of the dynamin-like guanosine
Proteolytic cleavage of the dynamin-like guanosine
Autor:
Martine Roovers, Udo Oppermann, Louis Droogmans, Corinne Gemperle-Britschgi, Henry J. Bailey, Michael Leichsenring, Wyatt W. Yue, Frauke Beermann, Alain Fouilhoux, Stephanie Oerum, Joern Oliver Sass, Anne Korwitz-Reichelt, Cecile Acquaviva-Bourdain
Publikováno v:
Biochimica et biophysica acta. Molecular basis of disease. 1863(12)
MRPP2 (also known as HSD10/SDR5C1) is a multifunctional protein that harbours both catalytic and non-catalytic functions. The protein belongs to the short-chain dehydrogenase/reductases (SDR) family and is involved in the catabolism of isoleucine in
Autor:
Thomas Langer, Thorsten Decker, Ines Lauria, Ricarda Richter-Dennerlein, Kavya Bakka, Angela Paggio, Maria Patron, Anne Korwitz, Mareike Mühlmeister, Ulrich Brandt, Elena I. Rugarli, Tim König, Simon E. Tröder, Rosario Rizzuto, Philipp A Lampe, Sergio Guerrero-Castillo, Diego De Stefani
Publikováno v:
Mol Cell
Molecular Cell, 64, 1, pp. 148-162
Molecular Cell, 64, 148-162
Molecular Cell, 64, 1, pp. 148-162
Molecular Cell, 64, 148-162
Item does not contain fulltext Mutations in subunits of mitochondrial m-AAA proteases in the inner membrane cause neurodegeneration in spinocerebellar ataxia (SCA28) and hereditary spastic paraplegia (HSP7). m-AAA proteases preserve mitochondrial pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86775fcfc9a16ac65450ff61970eb902
http://hdl.handle.net/11577/3206185
http://hdl.handle.net/11577/3206185
Autor:
Rodolfo Lavilla, Claudia M. Palmeri, Gabriel Pons, Sonia Núñez-Vázquez, José Saura-Esteller, Helena Pomares, Sara Preciado, Alba Pérez-Perarnau, Daniel Iglesias-Serret, Ana M. Cosialls, Diana M. González-Gironès, Thomas Langer, Joan Gil, Anne Korwitz, Fernando Albericio, Cristina Moncunill-Massaguer
Publikováno v:
Oncotarget
Recercat. Dipósit de la Recerca de Catalunya
instname
Dipòsit Digital de la UB
Universidad de Barcelona
Recercat. Dipósit de la Recerca de Catalunya
instname
Dipòsit Digital de la UB
Universidad de Barcelona
// Cristina Moncunill-Massaguer 1 , Jose Saura-Esteller 1 , Alba Perez-Perarnau 1 , Claudia Mariela Palmeri 1 , Sonia Nunez-Vazquez 1 , Ana M. Cosialls 1 , Diana M. Gonzalez-Girones 1 , Helena Pomares 1 , Anne Korwitz 2 , Sara Preciado 3 , Fernando A
Autor:
Mathias Haag, Michael J. Baker, Ricarda Richter-Dennerlein, Sascha Dargazanli, Elena I. Rugarli, Takashi Tatsuta, Anne Korwitz, Thomas Langer, Thorsten Decker, Tobias Lamkemeyer
Publikováno v:
Cell Metab
Cell Metabolism
Cell Metabolism
SummaryProhibitins form large protein and lipid scaffolds in the inner membrane of mitochondria that are required for mitochondrial morphogenesis, neuronal survival, and normal lifespan. Here, we have defined the interactome of PHB2 in mitochondria a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b03fef63704ed5fd4192707b2a5cef0c
https://hdl.handle.net/21.11116/0000-000B-72B7-6
https://hdl.handle.net/21.11116/0000-000B-72B7-6
Autor:
Arun Kumar Kondadi, Elena I. Rugarli, Michael J. Baker, Anne Korwitz, Paola Martinelli, Astrid Schauss, Sara Montagner, Thomas Langer, Nikolay Kladt, Shuaiyu Wang, David Herholz
Publikováno v:
EMBO J
The m-AAA protease subunit AFG(3)L(2) is involved in degradation and processing of substrates in the inner mitochondrial membrane. Mutations in AFG(3)L(2) are associated with spinocerebellar ataxia SCA28 in humans and impair axonal development and ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0cee1aa5c71a4d1abfb2d5be8c7356d
https://hdl.handle.net/21.11116/0000-000B-82BD-D
https://hdl.handle.net/21.11116/0000-000B-82BD-D
Autor:
Thomas Langer, Michael J. Baker, Ruchika Anand, Philipp A Lampe, Diana Stojanovski, Anne Korwitz, Takashi Tatsuta
Publikováno v:
EMBO J
The dynamic network of mitochondria fragments under stress allowing the segregation of damaged mitochondria and, in case of persistent damage, their selective removal by mitophagy. Mitochondrial fragmentation upon depolarisation of mitochondria is br
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4da23334610c470b9fe5ba05673398fa
https://europepmc.org/articles/PMC3989652/
https://europepmc.org/articles/PMC3989652/
Autor:
Alvaro Barrera-Ocampo, Kuikui Zhou, Chris I. De Zeeuw, María Fernanda Vinueza-Veloz, Haibo Zhou, Martijn Schonewille, Andrés Villegas, Markus Glatzel, Thomas Langer, Anne Korwitz, Francisco Lopera, Christian Hagel, Diego Sepulveda-Falla, Luis Velázquez-Pérez, Isidro Ferrer, Roberto Rodríguez-Labrada
Publikováno v:
Recercat. Dipósit de la Recerca de Catalunya
instname
Dipòsit Digital de la UB
Universidad de Barcelona
Journal of Clinical Investigation, 124(4), 1552-67. The American Society for Clinical Investigation
Journal of Clinical Investigation, 124(4), 1552-1567. The American Society for Clinical Investigation
J Clin Invest
instname
Dipòsit Digital de la UB
Universidad de Barcelona
Journal of Clinical Investigation, 124(4), 1552-67. The American Society for Clinical Investigation
Journal of Clinical Investigation, 124(4), 1552-1567. The American Society for Clinical Investigation
J Clin Invest
Familial Alzheimer's disease (FAD) is characterized by autosomal dominant heritability and early disease onset. Mutations in the gene encoding presenilin-1 (PS1) are found in approximately 80% of cases of FAD, with some of these patients presenting c