Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Anne Katrine Johansen"'
Autor:
Charlotte Demkes, Mauro Giacca, Bastiaan Spanjaard, Farhad Akbari Moqadam, Lieneke Kooijman, Hesther de Ruiter, Lorena Zentilin, D Versteeg, Bas Molenaar, Anne Katrine Johansen, Eva van Rooij, Ana Rita Leitoguinho
Publikováno v:
Circulation Research, 121(10), 1168-1181. Lippincott Williams & Wilkins
Rationale: CRISPR/Cas9 (clustered regularly interspaced palindromic repeats/CRISPR-associated protein 9)–based DNA editing has rapidly evolved as an attractive tool to modify the genome. Although CRISPR/Cas9 has been extensively used to manipulate
Autor:
Aikaterini Anagnostopoulou, Rhian M. Touyz, Kevin P. White, Katie Y Hood, Afshan Dean, Margaret R. MacLean, Ian Morecroft, Lynn Loughlin, Margaret Nilsen, Anne Katrine Johansen
Publikováno v:
Pulmonary Circulation. 6:82-92
Pulmonary arterial hypertension (PAH) is a devastating vasculopathy that predominates in women and has been associated with dysregulated estrogen and serotonin signaling. Overexpression of the serotonin transporter (SERT(+)) in mice results in an est
Autor:
Abdallah Alzoubi, Masahiko Oka, Stevan P. Tofovic, James West, Margaret R. MacLean, Anne Katrine Johansen, Eric D. Austin, Tim Lahm
Publikováno v:
Pulmonary Circulation
Most subtypes of pulmonary arterial hypertension (PAH) are characterized by a greater susceptibility to disease among females, although females with PAH appear to live longer after diagnosis. While this “estrogen paradoxȍ of enhanced female surviv
Autor:
Margaret Nilsen, Annabel S. Campbell, Anne Katrine Johansen, Ian Morecroft, Lynn Loughlin, Kirsty M. Mair, Leigh Paton, Margaret R. MacLean, Emma Wallace, Matthew Thomas, Kevin P. White, John D. McClure, Loredana Ciuclan
Publikováno v:
Circulation. 126:1087-1098
Background— Pulmonary arterial hypertension (PAH) is a hyperproliferative vascular disorder observed predominantly in women. Estrogen is a potent mitogen in human pulmonary artery smooth muscle cells and contributes to PAH in vivo; however, the mec
Pulmonary arterial hypertension (PAH) is a complex disease characterized by elevated pulmonary arterial pressure, pulmonary vascular remodelling and occlusive pulmonary vascular lesions, leading to right heart failure. Evidence from recent epidemiolo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dff4fd8293f85bef9a9f095f3754bb8f
https://europepmc.org/articles/PMC3969073/
https://europepmc.org/articles/PMC3969073/
Publikováno v:
D97. PULMONARY HYPERTENSION: NEW INSIGHTS INTO CAUSES AND TREATMENTS?.