Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Anne Karppinen"'
Autor:
Anne Karppinen
An unorthodox musician from the start, singer-songwriter Joni Mitchell's style of composing, performing, and of playing (and tuning) the guitar is unique. In the framework of sexual difference and the gendered discourses of rock this immediately begs
Publikováno v:
International Journal of Cancer. 104:380-388
Cancer gene therapy with the aid of herpes simplex virus type 1 thymidine kinase gene (HSV-TK) and anti-herpes drug ganciclovir (GCV) has been widely used and its efficacy has been demonstrated in a variety of different malignant cells and animal tum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::08f65589b79088fa880a1836ff03ed64
https://doi.org/10.1002/ijc.10942
https://doi.org/10.1002/ijc.10942
Autor:
Slavoljub Vujcic, Debora L. Kramer, Anne Karppinen, Maria Halmekytö, Ryan Hines, Mikko Uusi-Oukari, Carl W. Porter, Leena Alhonen, Veli-Pekka Korhonen, Juhani Jänne
Publikováno v:
Journal of Biological Chemistry. 273:1964-1969
A recently generated transgenic mouse line having activated polyamine catabolism due to systemic overexpression of spermidine/spermine N1-acetyltransferase (SSAT) was used to isolate primary fetal fibroblasts as a means to further elucidate the cellu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c323b01ad9866c2b7237438ed6f2882b
https://doi.org/10.1074/jbc.273.4.1964
https://doi.org/10.1074/jbc.273.4.1964
Autor:
Tuomo A. Keinänen, Patrick M. Woster, Pekka Uimari, Leena Alhonen, Anne Karppinen, Juhani Jänne, Anne Uimari
Publikováno v:
The Biochemical journal. 422(1)
SSAT (Spermidine/spermine N1-acetyltransferase, also known as SAT1), the key enzyme in the catabolism of polyamines, is turned over rapidly and there is only a low amount present in the cell. In the present study, the regulation of SSAT by spermine a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd6545da8d03ae2c8adb8b3a359f1709
https://pubmed.ncbi.nlm.nih.gov/19473115
https://pubmed.ncbi.nlm.nih.gov/19473115
Publikováno v:
International journal of oncology. 28(6)
We have shown earlier that polyamine biosynthesis inhibition is accompanied by cell cycle alterations that can be utilized to enhance the efficacy of herpes simplex virus thymidine kinase - ganciclovir (HSV-TK/GCV) cancer gene therapy. In the present
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e40fd91a3bc46a237d522b5d240b0ae6
https://pubmed.ncbi.nlm.nih.gov/16685452
https://pubmed.ncbi.nlm.nih.gov/16685452
Publikováno v:
International journal of cancer. 104(3)
Cancer gene therapy with the aid of herpes simplex virus type 1 thymidine kinase gene (HSV-TK) and anti-herpes drug ganciclovir (GCV) has been widely used and its efficacy has been demonstrated in a variety of different malignant cells and animal tum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::943144f4d0b6ea833bbe7240831303ee
https://pubmed.ncbi.nlm.nih.gov/12569563
https://pubmed.ncbi.nlm.nih.gov/12569563
Publikováno v:
Molecular Therapy. 11:S120
We have earlier demonstrated that inhibition of polyamine biosynthesis with difluoromethylornithine (DFMO, irreversible inhibitor of ornithine decarboxylase) can be used to enhance the cytotoxicity of HSV-TK/ganciclovir gene therapy in rat and human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd6f0fc8c46af99ea9cd4766a14014df
https://doi.org/10.1016/j.ymthe.2005.06.311
https://doi.org/10.1016/j.ymthe.2005.06.311