Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Anne Kamitz"'
Autor:
Heja Aga, Nicole Hallahan, Pascal Gottmann, Markus Jaehnert, Sophie Osburg, Gunnar Schulze, Anne Kamitz, Danny Arends, Gudrun Brockmann, Tanja Schallschmidt, Sandra Lebek, Alexandra Chadt, Hadi Al-Hasani, Hans-Georg Joost, Annette Schürmann, Heike Vogel
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Type 2 diabetes (T2D) is a complex metabolic disease regulated by an interaction of genetic predisposition and environmental factors. To understand the genetic contribution in the development of diabetes, mice varying in their disease susceptibility
Externí odkaz:
https://doaj.org/article/c1879ec999634ac1a25ae539c9841c9e
Autor:
Pascal Gottmann, Meriem Ouni, Sophie Saussenthaler, Julian Roos, Laura Stirm, Markus Jähnert, Anne Kamitz, Nicole Hallahan, Wenke Jonas, Andreas Fritsche, Hans-Ulrich Häring, Harald Staiger, Matthias Blüher, Pamela Fischer-Posovszky, Heike Vogel, Annette Schürmann
Publikováno v:
Molecular Metabolism, Vol 11, Iss , Pp 145-159 (2018)
Objective: Obesity and type 2 diabetes (T2D) arise from the interplay between genetic, epigenetic, and environmental factors. The aim of this study was to combine bioinformatics and functional studies to identify miRNAs that contribute to obesity and
Externí odkaz:
https://doaj.org/article/b43f895593b3447b9e47be298c257584
Autor:
Oliver Kluth, Daniela Matzke, Anne Kamitz, Markus Jähnert, Heike Vogel, Stephan Scherneck, Matthias Schulze, Harald Staiger, Fausto Machicao, Hans-Ulrich Häring, Hans-Georg Joost, Annette Schürmann
Publikováno v:
PLoS Genetics, Vol 11, Iss 9, p e1005506 (2015)
Beta-cell apoptosis and failure to induce beta-cell regeneration are hallmarks of type 2-like diabetes in mouse models. Here we show that islets from obese, diabetes-susceptible New Zealand Obese (NZO) mice, in contrast to diabetes-resistant C57BL/6J
Externí odkaz:
https://doaj.org/article/8b348edb041a42118e2de0ab5d3a5c2d
Autor:
Manuel Benito, Jesús Burillo, Beatriz Jiménez, Alberto Bartolomé, Patricia Marqués, Helena Hernández Martínez, María Fernández-Rhodes, Anne Kamitz, Carlos Guillén
Publikováno v:
Cell Death Discovery
Cell Death Discovery, Vol 5, Iss 1, Pp 1-11 (2019)
Cell Death Discovery, Vol 5, Iss 1, Pp 1-11 (2019)
Energy sensing is indispensable to balance anabolic and catabolic processes for the maintenance of cell viability. Pancreatic β cells are especially relevant because of their involvement in the coordination of insulin secretion when glucose concentr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c18229a76e0d097e7070c4c68b5acc00
http://europepmc.org/articles/PMC6769003
http://europepmc.org/articles/PMC6769003
Autor:
Katharina Stohlmann, Tony J. Collins, Andreas Meisel, Dirk Megow, Heiko Klawitter, Josef Priller, Vincent van Laak, Ulrich Dirnagl, Lars Neeb, Ingo Przesdzing, Susanne Thomsen, Dorette Freyer, Anne Kamitz, David W. Andrews, Philipp Mergenthaler, Anja Kahl
Publikováno v:
Proceedings of the National Academy of Sciences
Proceedings of the National Academy of Sciences; Vol 109
Proceedings of the National Academy of Sciences; Vol 109
The metabolic state of a cell is a key determinant in the decision to live and proliferate or to die. Consequently, balanced energy metabolism and the regulation of apoptosis are critical for the development and maintenance of differentiated organism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74d9ce6b2686ae4f2b5e690ba3f8e6ca