Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Anne K. Zaiss"'
Autor:
Kanagasabai Vadivel, Anne K. Zaiss, Yogesh Kumar, Frank M. Fabian, Ayman E. A. Ismail, Mark A. Arbing, Wallace G. Buchholz, William H. Velander, S. Paul Bajaj
Publikováno v:
Journal of Clinical Medicine, Vol 9, Iss 11, p 3684 (2020)
Current antifibrinolytic agents reduce blood loss by inhibiting plasmin active sites (e.g., aprotinin) or by preventing plasminogen/tissue plasminogen activator (tPA) binding to fibrin clots (e.g., ε-aminocaproic acid and tranexamic acid); however,
Externí odkaz:
https://doaj.org/article/8225ff1b319d465197425cdb0dec2bd3
Autor:
S. Paul Bajaj, Wallace G. Buchholz, Yogesh Kumar, William H. Velander, Anne K. Zaiss, Kanagasabai Vadivel, Frank M. Fabian, Ayman E.A. Ismail, Mark A. Arbing
Publikováno v:
Journal of Clinical Medicine
Volume 9
Issue 11
Journal of Clinical Medicine, Vol 9, Iss 3684, p 3684 (2020)
Volume 9
Issue 11
Journal of Clinical Medicine, Vol 9, Iss 3684, p 3684 (2020)
Current antifibrinolytic agents reduce blood loss by inhibiting plasmin active sites (e.g., aprotinin) or by preventing plasminogen/tissue plasminogen activator (tPA) binding to fibrin clots (e.g., &epsilon
aminocaproic acid and tranexamic acid)
aminocaproic acid and tranexamic acid)
Autor:
Sathya-Moorthy Ponnuraj, Denis Evseenko, Rodney M. Camire, Harvey R. Herschman, Anne K. Zaiss, Yogesh Kumar, Kanagasabai Vadivel, Matthew W. Bunce, S. Paul Bajaj, Ling Wu, Madhu S. Bajaj
Publikováno v:
The Journal of biological chemistry, vol 289, iss 45
Tissue factor pathway inhibitor-2 (TFPI-2) is a homologue of TFPI-1 and contains three Kunitz-type domains and a basic C terminus region. The N-terminal domain of TFPI-2 is the only inhibitory domain, and it inhibits plasma kallikrein, factor XIa, an
Publikováno v:
The Journal of Immunology. 191:3112-3118
CD20 is a tetraspanning membrane protein expressed on B lymphocytes. CD20 deficiency in both mice and humans has recently been shown to have deleterious effects on Ab responses to T-independent Ags; however, no effect on T-dependent immunity has been
Autor:
Blerina Ahmetaj-Shala, Lisa Berglund, Nicholas S. Kirkby, Anne K. Zaiss, Jane A. Mitchell, John L. Wallace, Jing Jiao, Maria F. Gomez, Melissa V. Chan, Eliana Garcia-Vaz, Elena F. Verdu, Harvey R. Herschman
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 113(2)
Cyclooxygenase-2 (COX-2) is an inducible enzyme that drives inflammation and is the therapeutic target for widely used nonsteroidal antiinflammatory drugs (NSAIDs). However, COX-2 is also constitutively expressed, in the absence of overt inflammation
Autor:
Erin M. Foley, Harvey R. Herschman, Arthur Catapang, Roger Lawrence, Jeffrey D. Esko, Ramon Alemany, Hamidreza Hoveida, Patrick Secrest, Anne K. Zaiss, Dmitry M. Shayakhmetov, Yu Yamaguchi, Lina S. Schneider
Publikováno v:
Journal of virology, vol 90, iss 1
Adeno-associated virus 2 (AAV2) and adenovirus 5 (Ad5) are promising gene therapy vectors. Both display liver tropism and are currently thought to enter hepatocytes in vivo through cell surface heparan sulfate proteoglycans (HSPGs). To test directly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8c59c7e5e5863fb067797e494f275cb
https://europepmc.org/articles/PMC4702579/
https://europepmc.org/articles/PMC4702579/
Autor:
Sharon A. Clark, Akosua Vilaysane, Daniel A. Muruve, H. Christopher Meijndert, Virginie Pétrilli, Anne K. Zaiss, Pina Colarusso, Matthew J. Cotter, Jürg Tschopp, Robin M. Yates
Publikováno v:
The Journal of Immunology. 182:7058-7068
Adenovirus is a nonenveloped dsDNA virus that activates intracellular innate immune pathways. In vivo, adenovirus-immunized mice displayed an enhanced innate immune response and diminished virus-mediated gene delivery following challenge with the ade
Autor:
Jason C. L. Spurrell, Gloria P. Bowen, Qiang Liu, Daniel A. Muruve, Thomas J. Wickham, Morley D. Hollenberg, Lee Anne Tibbles, Anne K. Zaiss, Mindy Lam, Stephen M. Robbins
Publikováno v:
Journal of Virology. 76:1559-1568
The use of adenovirus vectors for human gene therapy is limited by potent inflammatory responses that result in significant morbidity. In kidney-derived epithelial cells (REC), activation of extracellular signal-regulated kinase 1/2 (ERK) and p38 kin
Autor:
Arthur Catapang, Tomo-o Ishikawa, Chun Chu, Hidevaldo B. Machado, Jose S. Gil, Anne K. Zaiss, Scott W. Lowe, Harvey R. Herschman, Johannes Zuber, Jing Jiao
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 7, p e101263 (2014)
PLoS ONE, Vol 9, Iss 7, p e101263 (2014)
Prostaglandin-endoperoxide synthase 2 (PTGS2), also known as cyclooxygenase 2 (COX-2), plays a critical role in many normal physiological functions and modulates a variety of pathological conditions. The ability to turn endogenous COX-2 on and off in
Autor:
Jane A. Mitchell, John L. Wallace, Jing Jiao, Maria F. Gomez, Melissa V. Chan, Lisa Berglund, Nicholas S. Kirkby, Anne K. Zaiss, Harvey R. Herschman, Eliana Garcia-Vaz
Publikováno v:
The FASEB Journal. 28
Drugs such as diclofenac and celecoxib inhibit cyclo-oxygenase (COX)-2 to produce anti-inflammatory benefit, but also produce renal/cardiovascular toxicity by inhibition of constitutive COX-2 in the kidney. During inflammation COX-2 is rapidly induce