Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Anne K. Bergfeld"'
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e17403 (2011)
The major virulence factor of the neuroinvasive pathogen Escherichia coli K1 is the K1 capsule composed of α2,8-linked polysialic acid (polySia). K1 strains harboring the CUS-3 prophage modify their capsular polysaccharide by phase-variable O-acetyl
Externí odkaz:
https://doaj.org/article/e020ea4bd81040f0bc222f42cc34bdb0
Autor:
Ajit Varki, Heinz Läubli, Alyssa N. Crittenden, Christopher J. Gregg, Andrea E. Bingman, Oliver M. T. Pearce, Patrick Secrest, Annie N. Samraj, Sandra Diaz, Anne K. Bergfeld, Kalyan Banda, Nissi Varki
Publikováno v:
Proceedings of the National Academy of Sciences. 112:542-547
A well known, epidemiologically reproducible risk factor for human carcinomas is the long-term consumption of "red meat" of mammalian origin. Although multiple theories have attempted to explain this human-specific association, none have been conclus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eceb7b318760533641af7cb646c1e55b
https://doi.org/10.1073/pnas.1417508112
https://doi.org/10.1073/pnas.1417508112
Autor:
Pascal Gagneux, Sandra Diaz, Meave G. Leakey, Roger Lawrence, Darius Ghaderi, Anne K. Bergfeld, Ajit Varki, Oliver M. T. Pearce
Biosynthesis of the common mammalian sialic acid N -glycolylneuraminic acid (Neu5Gc) was lost during human evolution due to inactivation of the CMAH gene, possibly expediting divergence of the Homo lineage, due to a partial fertility barrier. Neu5Gc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7981f363b8515e82b0538d30945a4a3f
https://europepmc.org/articles/PMC5625913/
https://europepmc.org/articles/PMC5625913/
Publikováno v:
Journal of Biological Chemistry. 287:28865-28881
The two major mammalian sialic acids are N-acetylneuraminic acid and N-glycolylneuraminic acid (Neu5Gc). The only known biosynthetic pathway generating Neu5Gc is the conversion of CMP-N-acetylneuraminic acid into CMP-Neu5Gc, which is catalyzed by the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d82004886d4cdca591d11a1d678e2195
https://doi.org/10.1074/jbc.m112.363549
https://doi.org/10.1074/jbc.m112.363549
Autor:
Rudolf Geyer, Anne K. Bergfeld, Martina Mühlenhoff, Sebastian P. Galuska, Christina Bleckmann, Hildegard Geyer, René C Röhrich, Kai Maass
Publikováno v:
Analytical Chemistry. 82:2059-2066
Oligosialic and polysialic acids (oligo/polySia) are characterized by high structural diversity, because of different types of sialic acids and glycosidic linkages. Although several methods have been described for the analysis of oligo/polySia, only
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f2a7c77cebadd1490116644f389f554
https://doi.org/10.1021/ac902809q
https://doi.org/10.1021/ac902809q
Autor:
Nina K. Lorenzen, Ulrich Vogel, Heike Claus, Martina Mühlenhoff, Fabian Spielmann, Anne K. Bergfeld
Publikováno v:
Journal of Biological Chemistry. 284:6-16
Neisseria meningitidis serogroup C is a major cause of bacterial meningitis and septicaemia. This human pathogen is protected by a capsule composed of alpha2,9-linked polysialic acid that represents an important virulence factor. In the majority of s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed655a27702f4659077626b054ce1e11
https://doi.org/10.1074/jbc.m807518200
https://doi.org/10.1074/jbc.m807518200
Publikováno v:
Journal of Biological Chemistry. 282:22217-22227
Escherichia coli K1 is a leading pathogen in neonatal sepsis and meningitis. The K1 capsule, composed of alpha2,8-linked polysialic acid, represents the major virulence factor. In some K1 strains, phase-variable O-acetylation of the capsular polysacc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4056865499350d2df72db226cc58926b
https://doi.org/10.1074/jbc.m703044200
https://doi.org/10.1074/jbc.m703044200
Publikováno v:
Glycoscience: Biology and Medicine ISBN: 9784431548409
Glycoscience: Biology and Medicine ISBN: 9784431548362
Glycoscience: Biology and Medicine ISBN: 9784431548362
N-Glycolylneuraminic acid (Neu5Gc) is a sialic acid commonly found at the outermost position of glycan chains at the surface of most mammalian cells. The only known pathway for synthesis of Neu5Gc is the conversion of CMP-N-acetylneuraminic acid (CMP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be0aa7bc4b3cfcb5288fe0a9a1b17300
https://doi.org/10.1007/978-4-431-54841-6_169
https://doi.org/10.1007/978-4-431-54841-6_169
Autor:
Oliver M. T. Pearce, Jeremy Van Vleet, Roger Lawrence, Biswa Choudhury, Anne K. Bergfeld, Ajit Varki, Sandra Diaz, Jeffrey D. Esko
Publikováno v:
The FASEB Journal. 28
Metabolism of the major mammalian sialic acid N-glycolylneuraminic acid (Neu5Gc) generates N-glycolylglucosamine (GlcNGc) as a byproduct of its degradative pathway (1). Mammalian cells cultured wit...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2577f8141e8409745a28386b978a7428
https://doi.org/10.1096/fasebj.28.1_supplement.607.6
https://doi.org/10.1096/fasebj.28.1_supplement.607.6
Autor:
Anne K. Bergfeld, Ajit Varki
Publikováno v:
Handbook of Glycosyltransferases and Related Genes ISBN: 9784431542391
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c55440b3fb1d54b917fa98dbc31780e8
https://doi.org/10.1007/978-4-431-54240-7_133
https://doi.org/10.1007/978-4-431-54240-7_133