Zobrazeno 1 - 10
of 139
pro vyhledávání: '"Anne K Kenworthy"'
Autor:
Alex J B Kreutzberger, Volker Kiessling, Catherine A Doyle, Noah Schenk, Clint M Upchurch, Margaret Elmer-Dixon, Amanda E Ward, Julia Preobraschenski, Syed S Hussein, Weronika Tomaka, Patrick Seelheim, Iman Kattan, Megan Harris, Binyong Liang, Anne K Kenworthy, Bimal N Desai, Norbert Leitinger, Arun Anantharam, J David Castle, Lukas K Tamm
Publikováno v:
eLife, Vol 9 (2020)
Insulin secretion from β-cells is reduced at the onset of type-1 and during type-2 diabetes. Although inflammation and metabolic dysfunction of β-cells elicit secretory defects associated with type-1 or type-2 diabetes, accompanying changes to insu
Externí odkaz:
https://doaj.org/article/6a3003b24de34ef2a6a794b8fb9446e1
Publikováno v:
PLoS Pathogens, Vol 12, Iss 12, p e1006070 (2016)
Clostridium difficile infection affects a significant number of hospitalized patients in the United States. Two homologous exotoxins, TcdA and TcdB, are the major virulence factors in C. difficile pathogenesis. The toxins are glucosyltransferases tha
Externí odkaz:
https://doaj.org/article/67f1f3ec03564646b03be7b037d92564
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0127966 (2015)
Fluorescence Recovery After Photobleaching (FRAP) has been a versatile tool to study transport and reaction kinetics in live cells. Since the fluorescence data generated by fluorescence microscopy are in a relative scale, a wide variety of scalings a
Externí odkaz:
https://doaj.org/article/4de5f524c68a4c5c83d66363da7f39da
Autor:
Charles A Day, Anne K Kenworthy
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e34923 (2012)
Multivalent glycolipid binding toxins such as cholera toxin have the capacity to cluster glycolipids, a process thought to be important for their functional uptake into cells. In contrast to the highly dynamic properties of lipid probes and many lipi
Externí odkaz:
https://doaj.org/article/75ec1a832de54cfa805bf8fa4b3c2003
Publikováno v:
PLoS ONE, Vol 5, Iss 3, p e9806 (2010)
The process of autophagy involves the formation of autophagosomes, double-membrane structures that encapsulate cytosol. Microtubule-associated protein light chain 3 (LC3) was the first protein shown to specifically label autophagosomal membranes in m
Externí odkaz:
https://doaj.org/article/de9385b6ab1d4a589966149b12e1e5b1
Autor:
Anne K. Kenworthy
Publikováno v:
Biochemical Society Transactions. 51:855-869
The ability of cells to divide, migrate, relay signals, sense mechanical stimuli, and respond to stress all rely on nanoscale invaginations of the plasma membrane known as caveolae. The caveolins, a family of monotopic membrane proteins, form the inn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e89f474cdf02a6374d8271b3ece2f543
https://doi.org/10.1042/bst20221298
https://doi.org/10.1042/bst20221298
Autor:
Anne K. Kenworthy
Publikováno v:
Biophysical Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::313f9aa0299c758569bd0e3ab96c9f8b
https://doi.org/10.1016/j.bpj.2023.05.016
https://doi.org/10.1016/j.bpj.2023.05.016
Autor:
Bing Han, Alican Gulsevin, Sarah Connolly, Ting Wang, Brigitte Meyer, Jason Porta, Ajit Tiwari, Angie Deng, Louise Chang, Yelena Peskova, Hassane S. Mchaourab, Erkan Karakas, Melanie D. Ohi, Jens Meiler, Anne K. Kenworthy
Publikováno v:
J Biol Chem
Caveolin-1 (CAV1) is a membrane-sculpting protein that oligomerizes to generate flask-shaped invaginations of the plasma membrane known as caveolae. Mutations in CAV1 have been linked to multiple diseases in humans. Such mutations often interfere wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3262e8a2bce0ab029daea8a71ff1d5f7
https://europepmc.org/articles/PMC10124911/
https://europepmc.org/articles/PMC10124911/
Caveolins are a unique family of membrane remodeling proteins essential for building flaskshaped nanoscale plasma membrane invaginations that regulate signaling and stress responses in vertebrates known as caveolae. Recent evidence suggests that to g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3fb7037da904768291355bfe88b7a9f
https://doi.org/10.1101/2022.11.15.516482
https://doi.org/10.1101/2022.11.15.516482
Autor:
Alican Gulsevin, Bing Han, Jason C. Porta, Hassane S. Mchaourab, Jens Meiler, Anne K. Kenworthy
Publikováno v:
Biophysical Journal.
AlphaFold2 (AF2) has revolutionized the field of protein structural prediction. Here, we test its ability to predict the tertiary and quaternary structure of a previously undescribed scaffold with new folds and unusual architecture, the monotopic mem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d93a2a1e53071d87cb57df46ee73318
https://doi.org/10.1016/j.bpj.2022.11.011
https://doi.org/10.1016/j.bpj.2022.11.011