Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Anne K Gibson"'
Autor:
Justin T. Whitfield, Gerald A. Meininger, Michael E. Nance, Steven S. Segal, Yi Zhu, Kenneth S. Campbell, Laurin M. Hanft, Anne K. Gibson, Timothy L. Domeier, Kerry S. McDonald
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 309:H918-H925
The Frank-Starling mechanism, whereby increased diastolic filling leads to increased cardiac output, depends on increasing the sarcomere length ( Ls) of cardiomyocytes. Ventricular stiffness increases with advancing age, yet it remains unclear how su
Autor:
Jessica A Hiemstra, Anne K Gibson, Jan R Ivey, Melissa S Cobb, Christopher P Baines, Maike Krenz, Timothy L Domeier, Craig A Emter
Publikováno v:
Circulation Research. 115
Left ventricular (LV) hypertrophy is a common characteristic of heart failure with preserved ejection fraction (HFpEF). Our lab recently characterized a mini-swine model of LV hypertrophy induced by aortic banding (AB) that displays clinical features
Autor:
Kerry S. McDonald, Steven S. Segal, Cale J. Roberts, Laurin M. Hanft, Timothy L. Domeier, Anne K. Gibson
Cardiac dysfunction in the aged heart reflects abnormalities in cardiomyocyte Ca2+homeostasis including altered Ca2+cycling through the sarcoplasmic reticulum (SR). The ryanodine receptor antagonist dantrolene exerts antiarrhythmic effects by prevent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e192c53dfb1a1ae4d4a44e9b94c66359
https://europepmc.org/articles/PMC4166750/
https://europepmc.org/articles/PMC4166750/
Autor:
Kerry S. McDonald, Steven S. Segal, Anne K. Gibson, Michael E. Nance, Timothy L. Domeier, Laurin M. Hanft, Charmain A. Fernando
Publikováno v:
Biophysical Journal. 106:645a
The Frank-Starling mechanism, whereby increased cardiac filling leads to increased cardiac output, is dependent on cardiomyocyte sarcomere length (Ls). The relationship between Ls and left-ventricular pressure (LVP) in living (non-fixed) myocardium i