Reduced Thalamic Volume and Metabolites in Type 1 Diabetes with Polyneuropathy

Autor: Asbjørn Mohr Drewes, Poul Erik Jakobsen, Christina Brock, Birgitte Brock, Jens Brøndum Frøkjær, Solomon Tesfaye, Jesper Karmisholt, Anne Juhl, Tine Maria Hansen, Janusiya Anajan Muthulingam, Dinesh Selvarajah

Publikováno v: Hansen, T M, Frøkjær, J B, Selvarajah, D, Muthulingam, J A, Tesfaye, S, Juhl, A, Drewes, A M, Jakobsen, P E, Karmisholt, J, Brock, B & Brock, C 2022, ' Reduced Thalamic Volume and Metabolites in Type 1 Diabetes with Polyneuropathy ', Experimental and Clinical Endocrinology and Diabetes, vol. 130, no. 5, pp. 327-334 . https://doi.org/10.1055/a-1347-2579

Objective Thalamus is essential in processing of sensory information. This study explored the associations between thalamic volume and intra-thalamic metabolites and associations to clinical and experimental characteristics of sensory function in adu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7a29dba942f7d5a0e8b1b893f3033f9
https://vbn.aau.dk/da/publications/12d7cc25-2c80-442c-9c86-e93fc52040aa

Diabetic Neuropathy Influences Control of Spinal Mechanisms

Autor: Rasmus Bach Nedergaard, Christina Brock, Poul Erik Jakobsen, Anne Juhl, Theresa Meldgaard, Jesper Karmisholt, Carsten Dahl Mørch, Thomas Dahl Nissen, Birgitte Brock, Asbjørn Mohr Drewes

Publikováno v: Nedergaard, R B, Nissen, T D, Mørch, C D, Meldgaard, T, Juhl, A H, Jakobsen, P E, Karmisholt, J, Brock, B, Drewes, A M & Brock, C 2021, ' Diabetic Neuropathy Influences Control of Spinal Mechanisms ', Journal of Clinical Neurophysiology, vol. 38, no. 4, pp. 299-305 . https://doi.org/10.1097/WNP.0000000000000691

PURPOSE: Comprehensive evaluation of the upstream sensory processing in diabetic symmetrical polyneuropathy (DSPN) is sparse. The authors investigated the spinal nociceptive withdrawal reflex and the related elicited somatosensory evoked cortical pot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7abe24040ecf78a923ef7a1c1ea71171
https://pubmed.ncbi.nlm.nih.gov/32501945

Brain spectroscopy reveals that N-acetylaspartate is associated to peripheral sensorimotor neuropathy in type 1 diabetes

Autor: Jesper Karmisholt, Anne Juhl, Poul Erik Jakobsen, Birgitte Brock, Henrik Vorum, Asbjørn Mohr Drewes, Jens Brøndum Frøkjær, Carl Uggerhøj Andersen, Christina Brock, Tine Maria Hansen

Publikováno v: Hansen, T M, Brock, B, Juhl, A, Drewes, A M, Vorum, H, Andersen, C U, Jakobsen, P E, Karmisholt, J S, Frøkjær, J B & Brock, C 2019, ' Brain spectroscopy reveals that N-acetylaspartate is associated to peripheral sensorimotor neuropathy in type 1 diabetes ', Journal of Diabetes and its Complications, vol. 33, no. 4, pp. 323-328 . https://doi.org/10.1016/j.jdiacomp.2018.12.016
Hansen, T M, Brock, B, Juhl, A, Drewes, A M, Vorum, H, Andersen, C U, Jakobsen, P E, Karmisholt, J, Frøkjær, J B & Brock, C 2019, ' Brain spectroscopy reveals that N-acetylaspartate is associated to peripheral sensorimotor neuropathy in type 1 diabetes ', Journal of Diabetes and its Complications, vol. 33, no. 4, pp. 323-328 . https://doi.org/10.1016/j.jdiacomp.2018.12.016
Hansen, T M, Brock, B, Juhl, A, Drewes, A M, Vorum, H, Andersen, C U, Jakobsen, P E, Karmisholt, J, Frokjaer, J B & Brock, C 2019, ' Brain spectroscopy reveals that N-acetylaspartate is associated to peripheral sensorimotor neuropathy in type 1 diabetes ', Journal of Diabetes and its Complications, vol. 33, no. 4, pp. 323-328 . https://doi.org/10.1016/j.jdiacomp.2018.12.016

Aims: Emerging evidence shows, that distal symmetric peripheral neuropathy (DSPN) also involves alterations in the central nervous system. Hence, the aims were to investigate brain metabolites in white matter of adults with diabetes and DSPN, and to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3f6c92b9971c52040febe7698bc9a66
https://pure.au.dk/portal/da/publications/brain-spectroscopy-reveals-that-nacetylaspartate-is-associated-to-peripheral-sensorimotor-neuropathy-in-type-1-diabetes(fece78f8-6469-4161-8d02-5a4d981ff8fe).html

26-Week Treatment with Liraglutide Reduced Inflammatory Markers But Did Not Reverse Severe Polyneuropathy in Adults with Type 1 Diabetes: A Randomised, Double-Blind, Placebo-Controlled Trial

Autor: Sam Riahi, Hans Henrik Lervang, Asbjørn Mohr Drewes, Jesper Karmisholt, Holger Jon Møller, Adam D. Farmer, Anne Juhl, Christina Brock, Christian Stevns Hansen, Birgitte Brock, Poul Erik Jakobsen

Publikováno v: SSRN Electronic Journal.

BACKGROUND: The pathogenesis of diabetic polyneuropathy involves vascular, metabolic, immune-mediated and inflammatory pathways. Glucagon-like-peptide-1 receptor agonists, such as liraglutide, have shown anti-inflammatory properties. We hypothesised

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4d11385219fbf2f093109bc6e22b49dc
https://doi.org/10.2139/ssrn.3218713

Severe adverse effects related to dermal exposure to a glyphosate-surfactant herbicide

Autor: N E Ebbehøj, P V Madsen, T P Mariager, B Schmidt, Anne Juhl

Publikováno v: Mariager, T P, Madsen, P V, Ebbehøj, N E, Schmidt, B & Juhl, A 2013, ' Severe adverse effects related to dermal exposure to a glyphosate-surfactant herbicide ', Clinical Toxicology, vol. 51, no. 2, pp. 111-3 . https://doi.org/10.3109/15563650.2013.763951

This is a case of severe chemical burns following prolonged accidental exposure to a glyphosate-surfactant herbicide. The patient developed local swelling, bullae and exuding wounds. Neurological impairment followed affecting finger flexion and sensa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ec0232e9c94ed44f1ec00d2a68b32e7
https://doi.org/10.3109/15563650.2013.763951