Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Anne Hinds"'
Autor:
Erin Crossey, Senegal Carty, Fengzhi Shao, Jhonatan Henao-Vasquez, Alexandra B. Ysasi, Michelle Zeng, Anne Hinds, Ming Lo, Andrew Tilston-Lunel, Xaralabos Varelas, Matthew R. Jones, Alan Fine
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract The lymphatic system consists of a vessel network lined by specialized lymphatic endothelial cells (LECs) that are responsible for tissue fluid homeostasis and immune cell trafficking. The mechanisms for organ-specific LEC responses to envir
Externí odkaz:
https://doaj.org/article/d1b0a87cde6e49948d29b487f65ded98
Autor:
Keith A. Gagnon, Jessie Huang, Olivia T. Hix, Veronica W. Hui, Anne Hinds, Esther Bullitt, Jeroen Eyckmans, Darrell N. Kotton, Christopher S. Chen
Publikováno v:
APL Bioengineering, Vol 8, Iss 2, Pp 026126-026126-13 (2024)
Previous lung-on-chip devices have facilitated significant advances in our understanding of lung biology and pathology. Here, we describe a novel lung-on-a-chip model in which human induced pluripotent stem cell-derived alveolar epithelial type II ce
Externí odkaz:
https://doaj.org/article/156561785503486e81a4ba15a22d4b49
Autor:
Anukul T. Shenoy, Carolina Lyon De Ana, Emad I. Arafa, Isabelle Salwig, Kimberly A. Barker, Filiz T. Korkmaz, Aditya Ramanujan, Neelou S. Etesami, Alicia M. Soucy, Ian M. C. Martin, Brian R. Tilton, Anne Hinds, Wesley N. Goltry, Hasmeena Kathuria, Thomas Braun, Matthew R. Jones, Lee J. Quinton, Anna C. Belkina, Joseph P. Mizgerd
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
The maintenance of T resident memory (TRM) cells within pulmonary tissues is incompletely understood. Here the authors show that antigen presentation by lung epithelial cells maintains function and phenotype of pulmonary TRM cells within specific loc
Externí odkaz:
https://doaj.org/article/c4c893d49d55411c8e49e957418469ec
Autor:
Kristine M. Abo, Julio Sainz de Aja, Jonathan Lindstrom-Vautrin, Konstantinos-Dionysios Alysandratos, Alexsia Richards, Carolina Garcia-de-Alba, Jessie Huang, Olivia T. Hix, Rhiannon B. Werder, Esther Bullitt, Anne Hinds, Isaac Falconer, Carlos Villacorta-Martin, Rudolf Jaenisch, Carla F. Kim, Darrell N. Kotton, Andrew A. Wilson
Publikováno v:
JCI Insight, Vol 7, Iss 6 (2022)
Type 2 alveolar epithelial cells (AT2s), facultative progenitor cells of the lung alveolus, play a vital role in the biology of the distal lung. In vitro model systems that incorporate human cells, recapitulate the biology of primary AT2s, and interf
Externí odkaz:
https://doaj.org/article/42389eda8ce941c3bc455d6c05c41b76
Autor:
Ruobing Wang, Adam J. Hume, Mary Lou Beermann, Chantelle Simone-Roach, Jonathan Lindstrom-Vautrin, Jake Le Suer, Jessie Huang, Judith Olejnik, Carlos Villacorta-Martin, Esther Bullitt, Anne Hinds, Mahboobe Ghaedi, Stuart Rollins, Rhiannon B. Werder, Kristine M. Abo, Andrew A. Wilson, Elke Mühlberger, Darrell N. Kotton, Finn J. Hawkins
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 322:L462-L478
There is an urgent need to understand how SARS-CoV-2 infects the airway epithelium and in a subset of individuals leads to severe illness or death. Induced pluripotent stem cells (iPSCs) provide a near limitless supply of human cells that can be diff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c11daf317db3d8d2e025dfc4b0110bb
https://doi.org/10.1152/ajplung.00397.2021
https://doi.org/10.1152/ajplung.00397.2021
Autor:
Claire L Burgess, Jessie Huang, Pushpinder Bawa, Konstantinos-Dionysios Alysandratos, Kasey Minakin, Michael P Morley, Apoorva Babu, Carlos Villacorta-Martin, Anne Hinds, Bibek R Thapa, Feiya Wang, Adeline M Matschulat, Edward E Morrisey, Xaralabos Varelas, Darrell N Kotton
Publikováno v:
bioRxiv
In the distal lung, alveolar epithelial type I cells (AT1s) comprise the vast majority of alveolar surface area and are uniquely flattened to allow the diffusion of oxygen into the capillaries. This structure along with a quiescent, terminally differ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08e8b8485fb4c400a98169e1b1e1b898
https://europepmc.org/articles/PMC9882278/
https://europepmc.org/articles/PMC9882278/
Autor:
Anne Hinds, E.I. Arafa, Anukul T. Shenoy, Thomas Braun, Matthew R. Jones, Carolina Lyon De Ana, Filiz Korkmaz, Aditya Ramanujan, Neelou S. Etesami, Kimberly A. Barker, Hasmeena Kathuria, Joseph P. Mizgerd, Alicia M. Soucy, Anna C. Belkina, Brian R. Tilton, Wesley N. Goltry, I.M.C. Martin, Isabelle Salwig, Lee J. Quinton
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Nature Communications
Nature Communications
Barrier tissues are populated by functionally plastic CD4+ resident memory T (TRM) cells. Whether the barrier epithelium regulates CD4+ TRM cell locations, plasticity and activities remains unclear. Here we report that lung epithelial cells, includin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63fc2412b2ecaab97ee450408d6d92ec
https://doaj.org/article/c4c893d49d55411c8e49e957418469ec
https://doaj.org/article/c4c893d49d55411c8e49e957418469ec
Autor:
Rhiannon B. Werder, Tao Liu, Kristine M. Abo, Jonathan Lindstrom-Vautrin, Carlos Villacorta-Martin, Jessie Huang, Anne Hinds, Nathan Boyer, Esther Bullitt, Marc Liesa, Edwin K. Silverman, Darrell N. Kotton, Michael H. Cho, Xiaobo Zhou, Andrew A. Wilson
Publikováno v:
Science advances. 8(28)
Genome-wide association studies (GWAS) have identified dozens of loci associated with chronic obstructive pulmonary disease (COPD) susceptibility; however, the function of associated genes in the cell type(s) affected in disease remains poorly unders
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6080724d29fb0756ce5fbcad6ad99e0f
https://pubmed.ncbi.nlm.nih.gov/35857525
https://pubmed.ncbi.nlm.nih.gov/35857525
Autor:
Judith Olejnik, Aditya Mithal, Esther Bullitt, Gustavo Mostoslavsky, Anne Hinds, Carlos Villacorta-Martin, Elke Mühlberger, Adam J. Hume, Jonathan Lindstrom-Vautrin
Publikováno v:
Stem Cell Reports
Summary Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection leading to coronavirus disease 2019 (COVID-19) usually results in respiratory disease, but extrapulmonary manifestations are of major clinical interest. Intestinal symptom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8aa9f45fabac9a548d35dfc06217b992
https://doi.org/10.1016/j.stemcr.2021.02.019
https://doi.org/10.1016/j.stemcr.2021.02.019
Autor:
Joseph E Kaserman, Rhiannon B. Werder, Feiya Wang, Taylor Matte, Michelle I. Higgins, Mark Dodge, Jonathan Lindstrom-Vautrin, Anne Hinds, Esther Bullitt, Ignacio S. Caballero, Xu Shi, Robert E. Gerszten, Nicola Brunetti-Pierri, Marc Liesa, Carlos Villacorta-Martin, Anthony N. Hollenberg, Darrell N. Kotton, Andrew A. Wilson
Individuals homozygous for the pathogenic “Z” mutation in alpha-1 antitrypsin deficiency (AATD) are known to be at increased risk for chronic liver disease. That some degree of risk is similarly conferred by the heterozygous state, estimated to a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd9f7fbd45d0460140df381244d84521
https://doi.org/10.1101/2022.02.01.478663
https://doi.org/10.1101/2022.02.01.478663