Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Anne Hertenstein"'
Publikováno v:
The Lancet Oncology. 17:e529-e541
Summary Neurological complications of cancer and of anticancer treatments can be substantially disabling to patients, especially with classic chemotherapies. As a rare but important complication, targeted therapies might also result in similar unwant
Autor:
Felix Sahm, Michael Platten, Frank Winkler, Martina Ott, Zhen Dong, Ann Catherine Steffen, Markus Weiler, Wolfgang Wick, Edward W. Green, Sarah Löw, Hans Werner Pledl, Jonas Blaes, Markus Zorn, Dieter Lemke, Anne Hertenstein, Manfred Jugold
Publikováno v:
Oncotarget
// Dieter Lemke 1, 2, 3 , Hans-Werner Pledl 1, 2, 3 , Markus Zorn 4 , Manfred Jugold 5 , Ed Green 1, 6 , Jonas Blaes 1, 2 , Sarah Low 1, 2, 3 , Anne Hertenstein 1, 2, 3 , Martina Ott 1, 6 , Felix Sahm 1, 7, 8 , Ann-Catherine Steffen 1, 2 , Markus Wei
Autor:
Christiane A. Opitz, Andreas von Deimling, Ahmed Sadik, Michael Weller, Ulrich Sure, Michael Sabel, Michael Platten, Joachim P. Steinbach, Anca L. Grosu, Martin Bendszus, Stefan M. Pfister, Dietmar Krex, Tobias Kessler, Anne Hertenstein, David T.W. Jones, Ghazaleh Tabatabai, Wolfgang Wick, Melanie Bewerunge-Hudler, Damian Stichel, Guido Reifenberger, Angela Zacher, Felix Sahm
BACKGROUND: O(6)-methylguanine-DNA-methyltransferase (MGMT) promoter methylation status is a predictive biomarker in glioblastoma. We investigated whether this marker furthermore defines a molecularly distinct tumor subtype with clinically different
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::485501fc15764106ebd86189b69175a2
https://www.ncbi.nlm.nih.gov/pubmed/29016808
https://www.ncbi.nlm.nih.gov/pubmed/29016808
Autor:
Severino Urban, Markus Weiler, Martin Bendszus, David Milford, Matthias Osswald, Leonie Jestaedt, Anne Hertenstein, Sabine Heiland, Frank Winkler, Philipp Niclas Pfenning, Felix Sahm, Tobias Kessler, Michael Platten, Carmen Ruiz de Almodovar, Petra Rübmann, Wolfgang Wick, Andreas von Deimling, Antje Wick, Jonas Blaes
Publikováno v:
Oncotarget
// Tobias Kessler 1, * , Felix Sahm 3, 6, * , Jonas Blaes 1 , Matthias Osswald 1, 4 , Petra Rubmann 1 , David Milford 7 , Severino Urban 8 , Leonie Jestaedt 7 , Sabine Heiland 7 , Martin Bendszus 7 , Anne Hertenstein 2, 4 , Philipp-Niclas Pfenning 1
Autor:
Petra Rübmann, Michael Platten, Katrin Deumelandt, Jonas Blaes, Anne Hertenstein, Michael O. Breckwoldt, Tobias Kessler, Wolfgang Wick, Carina M. Thome, Jana K. Sonner
BACKGROUND: Malignant gliomas belong to the most aggressive neoplasms in humans. The interactions and intercellular communication between malignant and non-malignant cells in the tumor microenvironment are tumor-promoting and critically to improve th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acd245a722090883976c8b3e8cc4bd55
https://europepmc.org/articles/PMC5463658/
https://europepmc.org/articles/PMC5463658/
Autor:
Michael Platten, Felix Sahm, Anne Hertenstein, Martin Bendszus, Tobias Kessler, Wolfgang Wick, Ahmed Sadik, A. von Deimling
Background: O6-methylguanine-DNA-methyltransferase (MGMT) promoter methylation status is a biomarker for patients with glioblastoma treated with alkylating agents. We investigated whether this marker just predicts the efficacy of alkylating chemother
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47b57891c7a3a09b7294577400bd4b3c
https://europepmc.org/articles/PMC5463725/
https://europepmc.org/articles/PMC5463725/
Autor:
Dtw Jones, Gnana Prakash Balasubramanian, W. Wick, Michael Platten, Edward W. Green, Anne Hertenstein, Theresa Bunse, Felix Sahm, Lukas Bunse, Khwab Sanghvi
Publikováno v:
Europe PubMed Central
Background: Checkpoint inhibitors for cancer immunotherapy have been shown to unleash a subdued endogenous T-cell response against mutated tumor antigens, so-called neoepitopes. However, tumors with a low burden of non-synonymous mutations - includin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0da15d878360d98e7f849d2ae7b15ab8
https://europepmc.org/articles/PMC5463760/
https://europepmc.org/articles/PMC5463760/
Publikováno v:
JAMA oncology. 2(12)
Autor:
Diana Tichy, Sina Burth, Heinz Peter Schlemmer, Antje Wick, Lukas D. Weberling, Martha Nowosielski, Anne Hertenstein, Philipp Kickingereder, Wolfgang Wick, Oliver Eidel, Alexander Radbruch, Sarah Löw, David Bonekamp, Martin Bendszus
Background The purpose of this study was to determine the relevance of clinical data, apparent diffusion coefficient (ADC), and relative cerebral blood volume (rCBV) from dynamic susceptibility contrast (DSC) perfusion and the volume transfer constan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3da176e7813a37a22fd1840fecedbd07
https://europepmc.org/articles/PMC5744248/
https://europepmc.org/articles/PMC5744248/
Autor:
Michael Platten, Antje Wick, Frank Winkler, Thomas Hielscher, Wolfgang Wick, Benedikt Wiestler, Anne Hertenstein, Oliver Menn
Publikováno v:
Journal of neuro-oncology. 129(3)
Bevacizumab is frequently used in patients with progressive glioblastoma raising questions regarding frequency of treatments, dosage, duration of therapy and the possibility of tapering and discontinuation for selected patient groups. We retrospectiv