Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Anne Harbig"'
Autor:
Thorsten Stiewe, Linda Bittel, Marco Mernberger, Stephan Pleschka, Eva Böttcher-Friebertshäuser, Klaus Schughart, Torsten Steinmetzer, Anne Harbig, Andrea Nist
Publikováno v:
J Biol Chem
The Journal of biological chemistry
United States
The Journal of biological chemistry
United States
Cleavage of influenza virus hemagglutinin (HA) by host proteases is essential for virus infectivity. HA of most influenza A and B (IAV/IBV) viruses is cleaved at a monobasic motif by trypsin-like proteases. Previous studies have reported that transme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b13c3837fe791ac7045de4125a4e49b3
https://doi.org/10.1074/jbc.ra120.012635
https://doi.org/10.1074/jbc.ra120.012635
Autor:
Mikhail Matrosovich, Hannah Limburg, Elsayed M. Abdelwhab, Diana Kruhl, Jürgen Stech, David A. Stein, Anne Harbig, Dorothea Bestle, Hong M. Moulton, Eva Böttcher-Friebertshäuser
Publikováno v:
J Virol
Cleavage of the influenza A virus (IAV) hemagglutinin (HA) by host proteases is indispensable for virus replication. Most IAVs possess a monobasic HA cleavage site cleaved by trypsin-like proteases. Previously, the transmembrane protease TMPRSS2 was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce147e5beacf7a7e19df7d425af82389
https://doi.org/10.1128/jvi.00906-21
https://doi.org/10.1128/jvi.00906-21
Autor:
Oliver Pilgram, Aline Keils, Gerrit E. Benary, Janis Müller, Stefan Merkl, Sandrine Ngaha, Simon Huber, Florent Chevillard, Anne Harbig, Viktor Magdolen, Andreas Heine, Eva Böttcher-Friebertshäuser, Torsten Steinmetzer
Publikováno v:
European Journal of Medicinal Chemistry. 238:114437
A rational structure-based approach was employed to develop novel 3-amidinophenylalanine-derived matriptase inhibitors with improved selectivity against thrombin and factor Xa. Of all 23 new derivatives, several monobasic inhibitors exhibit high matr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::596ca53eb97d37935e8f489e4a18582a
https://doi.org/10.1016/j.ejmech.2022.114437
https://doi.org/10.1016/j.ejmech.2022.114437
Autor:
Anne Harbig
Publikováno v:
The FASEB Journal. 35
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca62bff2940738328a74649c35959afe
https://doi.org/10.1096/fasebj.2021.35.s1.04516
https://doi.org/10.1096/fasebj.2021.35.s1.04516
Autor:
Andreas Rembert Koczulla, Hans-Dieter Klenk, Julia Jaeger, Hannah Limburg, Dorothea Bestle, Hong M. Moulton, Leon N. Schulte, David A. Stein, Harshavardhan Janga, Kornelia Hardes, Janine Koepke, Bernd Schmeck, Eva Böttcher-Friebertshäuser, Anne Harbig
Publikováno v:
Journal of Virology
Cleavage of influenza virus hemagglutinin (HA) by host cell proteases is essential for virus infectivity and spread. We previously demonstrated in vitro that the transmembrane protease TMPRSS2 cleaves influenza A virus (IAV) and influenza B virus (IB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57d992e5e7e325f2dea835b738d3df67
https://pubmed.ncbi.nlm.nih.gov/31391268
https://pubmed.ncbi.nlm.nih.gov/31391268