Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Anne Hanneken"'
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 5, p 2712 (2021)
The identification of soluble fibroblast growth factor (FGF) receptors in blood and the extracellular matrix has led to the prediction that these proteins modulate the diverse biological activities of the FGF family of ligands in vivo. A recent struc
Externí odkaz:
https://doaj.org/article/50be81947c2e4e73b9e44602cd8e3c66
Autor:
Anne Hanneken, Silke Becker, Ludovic S. Mure, Fatima Abbas, Frans Vinberg, Satchidananda Panda, Bryan W. Jones
The retina, a highly metabolic tissue in the central nervous system, consumes the most oxygen and energy stores in the body by tissue mass/volume. Consequently, it is not surprising that retinal ischemia leads to a rapid loss of retinal light respons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef567e3cb2dcaa91b5809102d2bcb69d
https://doi.org/10.1101/2020.06.30.180497
https://doi.org/10.1101/2020.06.30.180497
Publikováno v:
Science
Sensing light without forming images In the rodent retina, intrinsically photosensitive retinal ganglion cells (ipRGCs) entrain circadian rhythms, modulate mood, and signal pupillary accommodation. Such responses are light-driven but not image-based.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55cd1007a51c9ddc68f4347613d99879
https://europepmc.org/articles/PMC7120228/
https://europepmc.org/articles/PMC7120228/
Autor:
M. Wade Calcutt, Yiannis Koutalos, Zsolt Ablonczy, Richard M. Caprioli, Anne Hanneken, David M. Anderson, Rosalie K. Crouch, Kevin L. Schey, Jeffrey M. Spraggins
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Scientific Reports
Scientific Reports
Stargardt disease is a juvenile onset retinal degeneration, associated with elevated levels of lipofuscin and its bis-retinoid components, such as N-retinylidene-N-retinylethanolamine (A2E). However, the pathogenesis of Stargardt is still poorly unde
Publikováno v:
Transactions of the American Ophthalmological Society. 115
To test the hypothesis that delayed dark adaptation in patients with macular degeneration is due to an excess of free unliganded opsin (apo-opsin) and a deficiency of the visual chromophore, 11A total of 50 human autopsy eyes were harvested from dono
Autor:
David M. Anderson, Rosalie K. Crouch, Kevin L. Schey, Nicholas P. Boyer, Anne Hanneken, Zsolt Ablonczy, Leopold Adler, Jeffrey M. Spraggins, Yiannis Koutalos
The bis-retinoid N-retinylidene-N-retinylethanolamine (A2E) is one of the major components of lipofuscin, a fluorescent material that accumulates with age in the lysosomes of the retinal pigment epithelium (RPE) of the human eye. Lipofuscin, as well
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1823ee23a02814059c4cdc9bd17cfadc
https://europepmc.org/articles/PMC4626405/
https://europepmc.org/articles/PMC4626405/
Autor:
Patrice W. Goletz, Zsolt Ablonczy, Rosalie K. Crouch, Lorie R. Blakeley, Kevin L. Schey, Danielle B. Gutierrez, Yiannis Koutalos, Anne Hanneken
Publikováno v:
Photochemical & Photobiological Sciences. 9:1513-1519
Orange autofluorescence from lipofuscin in the lysosomes of the retinal pigment epithelium (RPE) is a hallmark of aging in the eye. One of the major components of lipofuscin is A2E, the levels of which increase with age and in pathologic conditions,
Publikováno v:
Journal of Agricultural and Food Chemistry. 58:4001-4007
A long-standing yet controversial bioactivity attributed to polyphenols is their beneficial effects in vision. Although anecdotal case reports and in vitro research studies provide evidence for the visual benefits of anthocyanin-rich berries, rigorou
Publikováno v:
Investigative ophthalmologyvisual science. 54(2)
Purpose Visual hallucinations (VHs) occur in macular degeneration patients with poor vision but normal cognitive function. The underlying mechanisms are poorly understood. We report the identification of pharmaceutical agents that enhance VH and use
Publikováno v:
Proceedings of the National Academy of Sciences. 91:9170-9174
We have purified three acidic (FGF-1) and basic (FGF-2) fibroblast growth factor binding proteins (FGF-BP1, FGF-BP2, and FGF-BP3) from human plasma and calf serum and demonstrate the presence of these circulating FGF-BPs in blood. Each are truncated