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pro vyhledávání: '"Anne Hallas"'
Prostaglandins PGE2and PGF2αin Human Fetal Lung: Immunohistochemistry and Release from Organ Culture
Autor:
Rodney W. Kelly, Merete Giles, Robert Hume, David Cossar, Anne Hallas, Margaret Gourlay, Jeanne E. Bell
Publikováno v:
Experimental Lung Research. 18:259-273
Immunohistochemical studies in human fetal lung have shown that epithelial and endothelial cells are both strongly and equally reactive for PGE2. In contrast, epithelial PGF2 alpha reactivity varied between fetuses, in some as intense as endothelial
Publikováno v:
Blood. 87(2)
Recently, using immunohistochemical methods, we surprisingly found that endoplasmic reticulum glucose-6-phosphatase is present in human embryonic and fetal red blood cells (RBCs) but not in adult RBCs. The fact that an endoplasmic reticulum enzyme, w
Publikováno v:
In vitro cellulardevelopmental biology. Animal. 32(1)
Human fetal lung at 16-19 weeks gestation has a partially differentiated epithelium, and in organ culture, distal airsacs dilate and the epithelium autodifferentiates to type I and II pneumatocytes, processes regulated by endogenous prostaglandin PGE
Publikováno v:
Early human development. 42(2)
We have shown for the first time that the microsomal glucose-6-phosphatase enzyme protein is present in human embryonic and fetal red blood cells and the ontogeny of its expression has been determined. In the earliest embryos, red cells are predomina
Publikováno v:
Histochemistry. 101(6)
The objective of our study was to determine the cellular localisation of glucose-6-phosphatase in developing human kidney using monospecific antiserum and a standard immunohistochemical method (peroxidase-antiperoxidase, PAP) on formalin fixed and pa
Autor:
Merete Giles, Margaret Gourlay, Anne Hallas, Jeanne E. Bell, Rodney W. Kelly, Robert Hume, David Cossar
Publikováno v:
Experimental lung research. 19(3)
PGE2 and PGF2 alpha are released into the media of human fetal lung organ cultures in decreasing amounts with time. This decline in PGs is not due to culture failure or loss of synthetic capacity, which can be stimulated by fetal bovine serum, nor is
Autor:
Anne Hallas, Rodney W. Kelly, Merete Giles, Robert Hume, David Cossar, Margaret Gourlay, Jeanne E. Bell
Publikováno v:
Experimental cell research. 194(1)
Addition of PGE2, but not PGF2 alpha, to fetal lung organ cultures accelerates the process of self-differentiation with increased dilatation of terminal airsacs and differentiation of the epithelial lining. Indomethacin reduces the endogenous product