Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Anne H. Turberfield"'
Autor:
Amy L. Hughes, Aleksander T. Szczurek, Jessica R. Kelley, Anna Lastuvkova, Anne H. Turberfield, Emilia Dimitrova, Neil P. Blackledge, Robert J. Klose
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Here the authors discover that SET1 complexes function as transcription anti-termination factors that bind to CpG islands and protect low to moderately transcribed genes from the pervasive termination activity of the ZC3H4 complex.
Externí odkaz:
https://doaj.org/article/fa7131c1d5964b9e91a8afdc60047753
Autor:
David A. Brown, Vincenzo Di Cerbo, Angelika Feldmann, Jaewoo Ahn, Shinsuke Ito, Neil P. Blackledge, Manabu Nakayama, Michael McClellan, Emilia Dimitrova, Anne H. Turberfield, Hannah K. Long, Hamish W. King, Skirmantas Kriaucionis, Lothar Schermelleh, Tatiana G. Kutateladze, Haruhiko Koseki, Robert J. Klose
Publikováno v:
Cell Reports, Vol 20, Iss 10, Pp 2313-2327 (2017)
Chromatin modifications and the promoter-associated epigenome are important for the regulation of gene expression. However, the mechanisms by which chromatin-modifying complexes are targeted to the appropriate gene promoters in vertebrates and how th
Externí odkaz:
https://doaj.org/article/9b58edca6b994f178ed582935538118f
Autor:
Anna Lastuvkova, Anne H. Turberfield, Paula Dobrinić, Neil P. Blackledge, Nadezda A. Fursova, Miles K. Huseyin, Robert J. Klose, Emma L. Findlater
Publikováno v:
Genes & Development
bioRxiv
Genes Dev
bioRxiv
Genes Dev
Histone-modifying systems play fundamental roles in gene regulation and the development of multicellular organisms. Histone modifications that are enriched at gene regulatory elements have been heavily studied, but the function of modifications found
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84a556ff69356202b654d87e22eac2bc
Publikováno v:
EMBO Reports
Histone methylation plays fundamental roles in regulating chromatin‐based processes. With the discovery of histone demethylases over a decade ago, it is now clear that histone methylation is dynamically regulated to shape the epigenome and regulate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b07ec529a533b5985d53fe907999c913
https://pubmed.ncbi.nlm.nih.gov/26564907
https://pubmed.ncbi.nlm.nih.gov/26564907
Autor:
Haruhiko Koseki, Anne H. Turberfield, Manabu Nakayama, Takashi Kondo, Yoko Koseki, Robert J. Klose, Hamish W King
Publikováno v:
Nucleic Acids Research
CpG islands (CGIs) are associated with the majority of mammalian gene promoters and function to recruit chromatin modifying enzymes. It has therefore been proposed that CGIs regulate gene expression through chromatin-based mechanisms, however in most
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64e6ddcc5fd5545c8f439336269a9122