Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Anne H. Cutler"'
Cutting Edge: BAFF Regulates CD21/35 and CD23 Expression Independent of Its B Cell Survival Function
Autor:
Dianna E. Shea, Anne H. Cutler, Leonid Gorelik, Susan L. Kalled, Lihe Su, Greg Thill, Christine Ambrose, Sarah A. Bixler, Steven D. Miklasz, Martin L. Scott
Publikováno v:
The Journal of Immunology. 172:762-766
Herein we demonstrate that B cell-activating factor of the TNF family (BAFF), a B cell survival factor, also regulates CD21/35 and CD23 expression. BAFF blockade in wild-type mice down-modulates CD21/35 and CD23 on B cells while survival remains inta
Autor:
Joanna Groom, Susan L. Kalled, Anne H. Cutler, Carl Olson, Stephen A. Woodcock, Pascal Schneider, Jurg Tschopp, Teresa G. Cachero, Marcel Batten, Julie Wheway, Davide Mauri, Dana Cavill, Tom P. Gordon, Charles R. Mackay, Fabienne Mackay
Publikováno v:
Journal of Clinical Investigation. 109:59-68
Publikováno v:
Lupus. 10:9-22
The CD154=CD40 pathway is required for the development and progression of disease in a variety of autoimmune model systems. We have demonstrated previously that long-term anti-CD154 treatment of nephritic (SWR×NZB)F1 mice prolonged survival and pres
Publikováno v:
The Journal of Immunology. 160:2158-2165
Prior studies have demonstrated that treatment of young, prenephritic lupus-prone mice with Ab directed against CD40 ligand (CD40L) prolongs survival and decreases the incidence of severe nephritis. In this report, we show that for (SWR × NZB)F1 (SN
Autor:
Christopher D. Benjamin, Ellen Garber, Norma S. Kenyon, Yen Ming Hsu, Renee I. Shapiro, Linda C. Burkly, David M. Harlan, Janine Ferrant, Frederick R. Taylor, Susan L. Kalled, Anne H. Cutler, Hess Donna M, Allan D. Kirk
Publikováno v:
International immunology. 16(11)
Blockade of the CD154-CD40 co-stimulatory pathway with anti-CD154 mAbs has shown impressive efficacy in models of autoimmunity and allotransplantation. Clinical benefit was also demonstrated in systemic lupus erythematosus (SLE) and idiopathic thromb
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 167(3)
Autoimmunity results from a failure in central and/or peripheral tolerance; however, the events that initiate and maintain this dysfunction remain unclear. To better understand the mediators involved in autoimmunity, we investigated the cellular mech
Autor:
Janine L. Ferrant, Christopher D. Benjamin, Anne H. Cutler, Susan L. Kalled, Yen-Ming Hsu, Ellen A. Garber, Donna M. Hess, Renee I. Shapiro, Norma S. Kenyon, David M. Harlan, Allan D. Kirk, Linda C. Burkly, Frederick R. Taylor
Publikováno v:
International Immunology; Nov2004, Vol. 16 Issue 11, p1583-1594, 12p