Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Anne Gruaz-Guyon"'
Autor:
Aurélie, Prignon, Claire, Provost, Faisal, Alshoukr, Dominique, Wendum, Anne, Couvelard, Jacques, Barbet, Patricia, Forgez, Jean-Noël, Talbot, Anne, Gruaz-Guyon
Publikováno v:
Molecular pharmaceutics. 16(6)
Neurotensin receptor 1 (NTSR1) is overexpressed in human pancreatic ductal adenocarcinoma (PDAC). Specific noninvasive positron-emission tomography (PET) imaging probes may improve the diagnostic accuracy and the monitoring of therapy for patients wi
Autor:
Aurélie Prignon, Claire Provost, Jean-Noël Talbot, Françoise Montravers, Adrian D. Nunn, Laura E. Lantry, Aldo Cagnolini, Anne Gruaz-Guyon, Valérie Nataf
Publikováno v:
Nuclear Medicine and Biology. 42:92-98
Introduction AMBA is a bombesin analogue that binds to GRPr. In a mouse model of estrogen-dependent human breast cancer, we tested whether 68 Ga-AMBA can be used for PET detection of GRPr-expressing tumors and could be more accurate than 18 F-FDG to
Autor:
Anne Gruaz-Guyon, Jacques Barbet, Sandra Mendes, Jean-Noël Talbot, Abdelhak Jallane, Faisal Al-Shoukr, Luc Brans, Aurélie Prignon, Dirk Tourwé
Publikováno v:
Bioconjugate Chemistry. 22:1374-1385
Overexpression of the high affinity neurotensin receptor 1 (NTSR1), demonstrated in several human cancers, has been proposed as a new marker for human ductal pancreatic carcinoma and as an independent factor for poor prognosis for ductal breast cance
Autor:
Anne Gruaz-Guyon, André Pèlegrin, Anthony Romieu, Olivier Raguin, Marie-Claude Fournie-Zaluski, Jacques Barbet, Didier Pélaprat, Bernard P. Roques, François Chatelet
Publikováno v:
Angewandte Chemie International Edition. 44:4058-4061
F-FDG) have greatly improved the diag-nosis and staging of numerous tumors with somatostatin-receptor-subtype overexpression or active glucose metabo-lism,respectively.Thisentailedthedevelopmentofnumerousradiolabeled peptides that target other recept
Autor:
André Pèlegrin, Anne Gruaz-Guyon, Monique Dussaillant, William Rostène, Olivier Raguin, Jacques Barbet, Marc Hillairet de Boisferon, Cynthia Thiercelin
Publikováno v:
Bioconjugate Chemistry. 13:654-662
Radiolabeled peptides are emerging tools for diagnosis and therapy of tumors overexpressing receptors. However, binding to receptors expressed by nontumor tissues may cause toxicity. The objective of this study was to specifically enhance the binding
Autor:
Anne Gruaz-Guyon, William Rostène, Jacques Barbet, O. Raguin, Emmanuel Gautherot, Marc Hillairet de Boisferon, Corrine Manetti
Publikováno v:
Letters in Peptide Science. 4:331-339
The advantages of bivalent hapten-bearing peptides for the detection of tumours pretargeted with bispecific antibodies have been demonstrated. This technology is now considered for radioimmunotherapy and bivalent haptens designed to target131I are ne
Publikováno v:
International Journal of Cancer. 63:250-256
The efficiency of radioimmunotherapy with iodine-labelled antibodies is often limited by intracellular internalisation and catabolism after initial binding to the cellular targets. We have developed a technique called affinity enhancement system (AES
Autor:
Daniel Baty, Amélie Cornillon, Martine Pugnière, Ghislaine Behar, Isabelle Teulon, Anne Gruaz-Guyon, Françoise Roquet, Jean-Luc Teillaud, Patrick Chames, Faisal Al-Shoukr, André Pèlegrin
Publikováno v:
FEBS Journal
FEBS Journal, 2009, 276 (14), pp.3881-93. ⟨10.1111/j.1742-4658.2009.07101.x⟩
FEBS Journal, Wiley, 2009, 276 (14), pp.3881-93. ⟨10.1111/j.1742-4658.2009.07101.x⟩
FEBS Journal, Wiley, 2009, june (00), pp.00
FEBS Journal, 2009, 276 (14), pp.3881-93. ⟨10.1111/j.1742-4658.2009.07101.x⟩
FEBS Journal, Wiley, 2009, 276 (14), pp.3881-93. ⟨10.1111/j.1742-4658.2009.07101.x⟩
FEBS Journal, Wiley, 2009, june (00), pp.00
International audience; Single-domain antibodies (sdAbs), which occur naturally in camelids, are endowed with many characteristics that make them attractive candidates as building blocks to create new antibody-related therapeutic molecules. In this s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20e62ad09d5d7bd6a154fe2f239270f4
https://hal.science/hal-00420547
https://hal.science/hal-00420547
Autor:
Faisal Alshoukr, Cedric Rosant, Veronique Maes, Jallane Abdelhak, Olivier Raguin, Samuel Burg, Laure Sarda, Jacques Barbet, Dirk Tourwé, Didier Pelaprat, Anne Gruaz-Guyon
The increased expression of the neurotensin (NT) receptor NTS1 by different cancer cells, such as pancreatic adenocarcinoma and ductal breast cancer cells, as compared to normal epithelium. offers the opportunity to target these tumors with radiolabe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07ec5862097f1d8a813089dc5c137ab5
https://hdl.handle.net/20.500.14017/9d02dd52-1963-4f52-8008-e3f6c3a2ba6a
https://hdl.handle.net/20.500.14017/9d02dd52-1963-4f52-8008-e3f6c3a2ba6a
Autor:
Anne Gruaz-Guyon, F. Montravers, Cl. de Labriolle-Vaylet, Jacques Barbet, M. Malafosse, S. Askienazy, J.N. Talbot, C. Chastang, Cl. Billotey, Jean-Didier Rain, D. Gallot, Ch. Cywiner, G. Saumon, P.-O. Betton, F.P. Châtelet, Santos Carvajal-Gonzalez, Gérard Milhaud, A. Sézeur
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 13(18 Pt 2)
Purpose: Colorectal carcinoma is frequently accompanied by small lymph nodes metastases that often escape pathologic examination. We evaluated whether ex vivo radioimmunodetection with the Affinity Enhancement System (AES) could improve detection of