Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Anne Granger"'
Publikováno v:
PLoS ONE, Vol 14, Iss 9, p e0214829 (2019)
Tamoxifen is a mixed agonist/antagonist estrogen analogue that is frequently used to induce conditional gene deletion in mice using Cre-loxP mediated gene recombination. Tamoxifen is routinely employed in extremely high-doses relative to typical huma
Externí odkaz:
https://doaj.org/article/add5045f70bc482788ab2d59d78b525a
Autor:
Kristen N Stevens, Hakon Hakonarson, Cecilia E Kim, Pieter A Doevendans, Bobby P C Koeleman, Seema Mital, Jennifer Raue, Joseph T Glessner, John G Coles, Victor Moreno, Anne Granger, Stephen B Gruber, Peter J Gruber
Publikováno v:
PLoS ONE, Vol 5, Iss 5, p e10855 (2010)
Congenital heart disease (CHD) is the most common birth abnormality and the etiology is unknown in the overwhelming majority of cases. ISLET1 (ISL1) is a transcription factor that marks cardiac progenitor cells and generates diverse multipotent cardi
Externí odkaz:
https://doaj.org/article/132bd25ef1cd45e7ad612e10cb094c68
Autor:
Carol Anne Granger
Publikováno v:
European Journal of Integrative Medicine. 48:101934
Publikováno v:
PLoS ONE, Vol 14, Iss 9, p e0214829 (2019)
PLoS ONE
PLoS ONE
Tamoxifen is a mixed agonist/antagonist estrogen analogue that is frequently used to induce conditional gene deletion in mice using Cre-loxP mediated gene recombination. Tamoxifen is routinely employed in extremely high-doses relative to typical huma
Publikováno v:
Cell metabolism. 26(1)
At Cell Metabolism, we often banter that “all roads lead to metabolism.” Over the years, we have witnessed the spectacular growth and integration of the metabolism field with other disciplines such as cancer biology, microbiology, and neurobiolog
Publikováno v:
Cell metabolism. 25(3)
Despite being in the age of information technology, with a wealth of molecular data at our fingertips, relatively simple clinical parameters such as BMI and fasting glucose are used to diagnose complex metabolic disorders. These clinical markers have
Autor:
Anne-Laure Schang, Bruno Quérat, Anne Granger, Christian Bleux, Jean-Noël Laverrière, Joëlle Cohen-Tannoudji
Publikováno v:
Molecular Endocrinology. 27:74-91
GATA2 transcription factor and LIM homeodomain proteins Islet1 (ISL1) and LIM homeobox 3 (LHX3) are suspected to be involved in gonadotrope cell fate and maintenance. The GnRH receptor gene (Gnrhr), crucial for gonadotrope function, is expressed in t
Autor:
Anne Granger, Nikla Emambokus
Publikováno v:
Cell metabolism. 24(3)
“How do you deal with data manipulation and retractions?” Indicative of the nebulous nature of the issue, this is a question often posed to us in hushed tones, late at night at meetings or toward the end of a phone call. Though certainly not our
Autor:
Solange Magre, Valerie Ngô-Muller, Marie-Claude Chenut, Muhammad Ishaq, Anne Granger, Anne-Laure Schang, Jean-Noël Laverrière, Christian Bleux, Joëlle Cohen-Tannoudji, Raymond Counis
Publikováno v:
Annals of the New York Academy of Sciences. 1220:16-22
In the pituitary of mammals, the GnRH receptor (GnRHR) plays crucial roles in the neuroendocrine control of reproductive function. This receptor is specifically expressed by the gonadotrope cells scattered among the five other endocrine cell types co
Publikováno v:
Cell Metabolism. 24:643-644
Otto Warburg is generally credited to be the “father” of cancer metabolism for his seminal discovery of how cancer cells predominantly generate energy through glycolysis rather than oxidative phosphorylation, even in the presence of oxygen. While