Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Anne Gegonne"'
Autor:
Sheetal Uppal, Anne Gegonne, Qingrong Chen, Petria S. Thompson, Dan Cheng, Jie Mu, Daoud Meerzaman, Hari S. Misra, Dinah S. Singer
Publikováno v:
Cell Reports, Vol 29, Iss 8, Pp 2450-2460.e5 (2019)
Summary: The bromodomain protein 4 (BRD4) is an atypical kinase and histone acetyl transferase (HAT) that binds to acetylated histones and contributes to chromatin remodeling and early transcriptional elongation. During transcription, BRD4 travels wi
Externí odkaz:
https://doaj.org/article/a0a7baa9ece248b081b81f1d1e967938
Autor:
Anne Gegonne, Qing-Rong Chen, Anup Dey, Ruth Etzensperger, Xuguang Tai, Alfred Singer, Daoud Meerzaman, Keiko Ozato, Dinah S. Singer
Publikováno v:
Cell Reports, Vol 24, Iss 1, Pp 117-129 (2018)
Summary: T cell differentiation in the thymus proceeds in an ordered sequence of developmental events characterized by variable expression of CD4 and CD8 coreceptors. Here, we report that immature single-positive (ISP) thymocytes are molecularly dist
Externí odkaz:
https://doaj.org/article/69f3e19e9a5c4397a55ab00523c4b6eb
Autor:
Dan Cheng, Kevin Semmens, Elizabeth McManus, Qingrong Chen, Daoud Meerzaman, Xiantao Wang, Markus Hafner, Brian A. Lewis, Hidehisa Takahashi, Ballachanda N. Devaiah, Anne Gegonne, Dinah S. Singer
Publikováno v:
Science Advances
Description
Transcription factor TAF7 links transcription and translation by delivering its transcripts to polysomes for translation.
The TFIID component, TAF7, has been extensively characterized as essential for transcription and is critic
Transcription factor TAF7 links transcription and translation by delivering its transcripts to polysomes for translation.
The TFIID component, TAF7, has been extensively characterized as essential for transcription and is critic
Autor:
Qing-Rong Chen, Sheetal Uppal, Hari S. Misra, Dinah S. Singer, Anne Gegonne, Petria S. Thompson, Jie Mu, Daoud Meerzaman, Dan Cheng
Publikováno v:
Cell Reports, Vol 29, Iss 8, Pp 2450-2460.e5 (2019)
Summary: The bromodomain protein 4 (BRD4) is an atypical kinase and histone acetyl transferase (HAT) that binds to acetylated histones and contributes to chromatin remodeling and early transcriptional elongation. During transcription, BRD4 travels wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61751a7939ddf1c7ff72b794deb65f44
https://europepmc.org/articles/PMC6893865/
https://europepmc.org/articles/PMC6893865/
Autor:
Daoud Meerzaman, Xuguang Tai, Alfred Singer, Ruth Etzensperger, Anup Dey, Dinah S. Singer, Keiko Ozato, Anne Gegonne, Qing-Rong Chen
Publikováno v:
Cell Reports, Vol 24, Iss 1, Pp 117-129 (2018)
Cell reports
Cell reports
SUMMARY T cell differentiation in the thymus proceeds in an ordered sequence of developmental events characterized by variable expression of CD4 and CD8 coreceptors. Here, we report that immature single-positive (ISP) thymocytes are molecularly disti
Bromodomain protein 4 (BRD4) is an atypical kinase and a histone acetyl transferase (HAT) which plays an important role in chromatin remodeling and early transcriptional elongation. During transcription elongation, BRD4 travels with the elongation co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::516099a1fd55cff76111dbc3871d3c53
Autor:
Daoud Meerzaman, Anup Dey, Chanelle Case-Borden, Dinah S. Singer, Chih Hao Hsu, Qing-Rong Chen, Anne Gegonne, Ballachanda N. Devaiah, Keiko Ozato
Publikováno v:
Nat Struct Mol Biol
Bromodomain protein 4 (BRD4) is a chromatin-binding protein implicated in cancer and autoimmune diseases that functions as a scaffold for transcription factors at promoters and super-enhancers. Although chromatin decompaction and transcriptional acti
Autor:
Xuguang Tai, Anne Gegonne, Ruth Etzensperger, Daoud Meerzaman, Keiko Ozato, Dinah S. Singer, Qing-Rong Chen, Anup Dey, Alfred Singer
The bromodomain protein BRD4 is a driver in both inflammatory diseases and cancers. It has multiple functions, contributing to chromatin structure and transcription through its intrinsic HAT and kinase activities. Despite the wide-ranging characteriz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::288c628af85bad2ec14d92e77ae15ddd
https://doi.org/10.1101/245662
https://doi.org/10.1101/245662
Publikováno v:
Transcription. 4:29-33
TAF7, a component of the TFIID complex, controls the first steps of transcription. It interacts with and regulates the enzymatic activities of transcription factors that regulate RNA polymerase II progression. Its diverse functions in transcription i
Publikováno v:
Journal of leukocyte biology. 100(4)
Bromodomain protein 4 (BRD4) is a transcriptional and epigenetic regulator that plays a pivotal role in cancer and inflammatory diseases. BRD4 binds and stays associated with chromatin during mitosis, bookmarking early G1 genes and reactivating trans