Zobrazeno 1 - 10
of 247
pro vyhledávání: '"Anne Gatignol"'
Publikováno v:
Retrovirology, Vol 21, Iss 1, Pp 1-20 (2024)
Abstract Human immunodeficiency virus (HIV) and human T cell leukemia virus (HTLV) have replicative and latent stages of infection. The status of the viruses is dependent on the cells that harbour them and on different events that change the transcri
Externí odkaz:
https://doaj.org/article/18956beaf97b4d17ad061a534a53541a
Autor:
Ryan P. Goguen, Olivier Del Corpo, Camille M.G. Malard, Aïcha Daher, Sergio P. Alpuche-Lazcano, Michelle J. Chen, Robert J. Scarborough, Anne Gatignol
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 23, Iss , Pp 1020-1034 (2021)
The expression of short hairpin RNAs (shRNAs) in cells has many potential therapeutic applications, including as a functional cure for HIV. The RNA polymerase III promoters H1, 7SK, and U6 have all been used to express shRNAs. However, there have bee
Externí odkaz:
https://doaj.org/article/5c5eb089f6c0434f859658bd9d510f3c
Autor:
Olivier Del Corpo, Ryan P. Goguen, Camille M.G. Malard, Aïcha Daher, Susan Colby-Germinario, Robert J. Scarborough, Anne Gatignol
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 18, Iss , Pp 815-830 (2019)
U1 interference (U1i) RNAs can be designed to correct splicing defects and target pathogenic RNA, such as HIV-1 RNA. In this study, we show that U1i RNAs that enhance HIV-1 RNA splicing are more effective at inhibiting HIV-1 production compared to to
Externí odkaz:
https://doaj.org/article/206069a0580241bc868024ce2fed03c8
Autor:
Sergio P Alpuche-Lazcano, James Saliba, Vivian V Costa, Gabriel H Campolina-Silva, Fernanda M Marim, Lucas S Ribeiro, Volker Blank, Andrew J Mouland, Mauro M Teixeira, Anne Gatignol
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 5, p e0009425 (2021)
Zika virus (ZIKV) infection of neurons leads to neurological complications and congenital malformations of the brain of neonates. To date, ZIKV mechanism of infection and pathogenesis is not entirely understood and different studies on gene regulatio
Externí odkaz:
https://doaj.org/article/435c988ad546417cb6504fb2c5fd46d2
Autor:
Damien Vitour, Sébastien Nisole, Nicolas Lévêque, Aure Saulnier, Noël Tordo, Anne Gatignol, David Gilmer
Publikováno v:
Virologie. 26:405-408
Publikováno v:
Expert Opinion on Drug Discovery. 18:163-179
Long-term control of HIV-1 infection can potentially be achieved using autologous stem cell transplants with gene-modified cells. Non-coding RNAs represent a diverse class of therapeutic agents including ribozymes, RNA aptamers and decoys, small inte
Publikováno v:
Retrovirology, Vol 14, Iss 1, Pp 1-14 (2017)
Externí odkaz:
https://doaj.org/article/f217e09fbe1b410fbc1c9fc16ada5a02
Autor:
Sergio P. Alpuche-Lazcano, Owen R. S. Dunkley, Robert J. Scarborough, Sylvanne M. Daniels, Aïcha Daher, Marin Truchi, Mario C. Estable, Bernard Mari, Andrew J. Mouland, Anne Gatignol
Micro (mi)RNAs are critical regulators of gene expression in human cells, the functions of which can be affected during viral replication. Here, we show that the human immunodeficiency virus type 1 (HIV-1) structural precursor Gag protein interacts w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a7c519e37863b9594f74ca3a7cfa7a2
https://doi.org/10.1101/2023.05.24.542197
https://doi.org/10.1101/2023.05.24.542197
Publikováno v:
Journal of Virus Eradication, Vol 3, Iss , Pp 10- (2017)
Externí odkaz:
https://doaj.org/article/b8f8f5a59f2e4b07aae556c610fdce60
Publikováno v:
Virologie (Montrouge, France). 26(1)