Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Anne G. Leary"'
Autor:
Johanna Olweus, Makio Ogawa, David William Buck, Sheri Miraglia, Graça Almeida-Porada, Esmail D. Zanjani, Anne G. Leary, John F. Kearney, Amy Yin
Publikováno v:
Blood. 90:5002-5012
AC133 is one of a new panel of murine hybridoma lines producing monoclonal IgG antibodies (mAbs) to a novel stem cell glycoprotein antigen with a molecular weight of 120 kD. AC133 antigen is selectively expressed on CD34bright hematopoietic stem and
Autor:
Judith Bard, Leonard D. Shultz, Helen Yeoman, Dominick DeLuca, Anne G. Leary, Edward A. Boyse, Catherine V. Bare, Ronald E. Gress, David T. Harris
Publikováno v:
Proceedings of the National Academy of Sciences. 90:10778-10782
Murine fetal thymus lobes isolated from both normal and scid/scid mice can be colonized by donor cells from either human bone marrow or human umbilical cord blood in vitro. Subsequent organ culture results in a transient production of a few CD4+ CD8+
Publikováno v:
Blood. 75:1960-1964
Leukemia inhibitory factor (LIF)/differentiation-inhibiting activity (DIA)/human interleukin for DA cells (HILDA) is a cytokine with biologic activities involving a variety of different types of target cells. Here we have tested LIF/DIA for possible
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 89(9)
In this study we have isolated populations of dormant human hemopoietic progenitors by two different approaches. First CD34+ cells isolated by panning were further separated on the basis of absence of HLA-DR expression by using fluorescence-activated
Autor:
Tatsutoshi Nakahata, Makio Ogawa, Anne G. Leary, Kimishige Ishizaka, A R Sterk, Teruko Ishizaka
Publikováno v:
Proceedings of the National Academy of Sciences. 80:4494-4498
Selective growth of human mast cells/basophils was obtained in suspension cultures of mononuclear cells from umbilical cord blood. A fraction of culture supernatant of phytohemagglutinin-stimulated T cells, which lacked interleukin 2, was required fo
Autor:
Makio Ogawa, Anne G. Leary
Publikováno v:
Blood. 69:953-956
We previously described candidate human blast cell colonies in culture of umbilical cord blood cells. However, their replating efficiencies were low, and we were unable to grow colonies from adult marrow cells. We report here a consistent method of g
Publikováno v:
Blood. 70:1343-1348
The genetic sequences encoding the gibbon and human interleukin 3 (IL 3) proteins were molecularly cloned. The amino acid sequence of the mature gibbon IL 3 protein proved to share 93% homology with the corresponding human protein. We examined the ef
Publikováno v:
Blood. 66:327-332
We analyzed the differentiation of hemopoietic colonies derived from human paired daughter cells. Candidate progenitor cells were isolated by use of a micromanipulation technique from cultures of My-10 antigen- positive cord blood cells. Then nine to
Autor:
Makio Ogawa, Anne G. Leary
Publikováno v:
Blood. 64:78-83
We present a colony assay system that allows in situ identification of human basophil/mast cell (basophil) colonies. In methylcellulose culture, in the presence of phytohemagglutinin-leukocyte conditioned media (PHA-LCM), human peripheral blood and b
Publikováno v:
Proceedings of the National Academy of Sciences. 86:4535-4538
Although it is generally held that hemopoietic stem cells in steady-state marrow are dormant in the cell cycle, the direct proof for this concept has been lacking. In the present study, we have documented the development of human multipotential blast