Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Anne G. Bang"'
Autor:
Ben Boyarko, Sonia Podvin, Barry Greenberg, Jeremiah D. Momper, Yadong Huang, William H. Gerwick, Anne G. Bang, Luisa Quinti, Ana Griciuc, Doo Yeon Kim, Rudolph E. Tanzi, Howard H. Feldman, Vivian Hook
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Therapeutics discovery and development for Alzheimer’s disease (AD) has been an area of intense research to alleviate memory loss and the underlying pathogenic processes. Recent drug discovery approaches have utilized in silico computational strate
Externí odkaz:
https://doaj.org/article/d3f3f5cf111246e3bec8557366792dd9
Autor:
Deborah Pré, Alexander T. Wooten, Steven Biesmans, Sandy Hinckley, Haowen Zhou, Sean P. Sherman, Priyanka Kakad, Jeffrey Gearhart, Anne G. Bang
Publikováno v:
Stem Cell Reports, Vol 18, Iss 1, Pp 412- (2023)
Externí odkaz:
https://doaj.org/article/f23c50984ddd420dac008a62ec997763
Autor:
Neha R. Dhoke, Hyunkee Kim, Sridhar Selvaraj, Karim Azzag, Haowen Zhou, Nelio A.J. Oliveira, Sudheer Tungtur, Carolina Ortiz-Cordero, James Kiley, Qi Long Lu, Anne G. Bang, Rita C.R. Perlingeiro
Publikováno v:
Cell Reports, Vol 36, Iss 2, Pp 109360- (2021)
Summary: Mutations in the fukutin-related protein (FKRP) gene result in a broad spectrum of muscular dystrophy (MD) phenotypes, including the severe Walker-Warburg syndrome (WWS). Here, we develop a gene-editing approach that replaces the entire muta
Externí odkaz:
https://doaj.org/article/6c28b824295349c796db8b9112b5789f
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Despite advancements in the development of cell-based in-vitro neuronal network models, the lack of appropriate computational tools limits their analyses. Methods aimed at deciphering the effective connections between neurons from extracellular spike
Externí odkaz:
https://doaj.org/article/55eb21003c7d4d628198467a5310af71
Autor:
Sean P. Sherman, Anne G. Bang
Publikováno v:
Disease Models & Mechanisms, Vol 11, Iss 2 (2018)
Development of technology platforms to perform compound screens of human induced pluripotent stem cell (hiPSC)-derived neurons with relatively high throughput is essential to realize their potential for drug discovery. Here, we demonstrate the feasib
Externí odkaz:
https://doaj.org/article/6a47be523b7f419682ae98538dcfbdbb
Autor:
Do Hyung Kim, Rita C.R. Perlingeiro, Anne G. Bang, Carolina Ortiz-Cordero, Haowen Zhou, Sridhar Selvaraj, Alessandro Magli, Claudia Bincoletto, Neha R. Dhoke
Publikováno v:
Stem Cell Reports
Summary Fukutin-related protein (FKRP) is a glycosyltransferase involved in glycosylation of alpha-dystroglycan (α-DG). Mutations in FKRP are associated with muscular dystrophies (MD) ranging from limb-girdle LGMDR9 to Walker-Warburg Syndrome (WWS),
Autor:
Deborah Pré, Alexander T. Wooten, Steven Biesmans, Sandy Hinckley, Haowen Zhou, Sean P. Sherman, Priyanka Kakad, Jeffrey Gearhart, Anne G. Bang
Publikováno v:
Stem cell reports. 17(9)
Impairment of long-term potentiation (LTP) is a common feature of many pre-clinical models of neurological disorders; however, studies in humans are limited by the inaccessibility of the brain. Human induced pluripotent stem cells (hiPSCs) provide a
Autor:
Renata Santos, Fred H. Gage, Anne G. Bang, Arianna Mei, Dekel Galor, Martin Alda, Shani Stern, Tchelet Stern, Yam Stern, Maria C. Marchetto, Anindita Sarkar, Lynne Randolph-Moore, Ana P.D. Mendes, Guy A. Rouleau
Publikováno v:
Biological Psychiatry. 88:150-158
Background We recently reported a hyperexcitability phenotype displayed in dentate gyrus granule neurons derived from patients with bipolar disorder (BD) as well as a hyperexcitability that appeared only in CA3 pyramidal hippocampal neurons that were
Autor:
Katelyn Daman, Dongsheng Guo, Jennifer JC Chen, Meng-Jiao Shi, Jing Yan, Zdenka Matijasevic, Amanda M Rickard, Monica H Bennett, Alex Kiselyov, Haowen Zhou, Anne G Bang, Kathryn R Wagner, René Maehr, Oliver D King, Lawrence J Hayward, Charles P Emerson
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b391c162ae6d9e4f68d0a2c4485d31d
https://doi.org/10.7554/elife.70341.sa2
https://doi.org/10.7554/elife.70341.sa2
Autor:
Haowen Zhou, Rita C.R. Perlingeiro, Nélio A. J. Oliveira, Carolina Ortiz-Cordero, Karim Azzag, Neha R. Dhoke, Qi Long Lu, James Kiley, Anne G. Bang, Sridhar Selvaraj, Hyunkee Kim, Sudheer Tungtur
Publikováno v:
Cell Reports, Vol 36, Iss 2, Pp 109360-(2021)
Cell reports
Cell reports
SUMMARY Mutations in the fukutin-related protein (FKRP) gene result in a broad spectrum of muscular dystrophy (MD) phenotypes, including the severe Walker-Warburg syndrome (WWS). Here, we develop a gene-editing approach that replaces the entire mutan