Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Anne G, Savitt"'
Autor:
Berhane Ghebrehiwet, Michal Zaniewski, Audrey Fernandez, Mathew DiGiovanni, Tiana N. Reyes, Ping Ji, Anne G. Savitt, Jennie L. Williams, Markus A. Seeliger, Ellinor I. B. Peerschke
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Understanding at the molecular level of the cell biology of tumors has led to significant treatment advances in the past. Despite such advances however, development of therapy resistance and tumor recurrence are still unresolved major challenges. Thi
Externí odkaz:
https://doaj.org/article/9414afff38834c27959bcaf27d0e7a86
Autor:
Annika Sünderhauf, Maren Hicken, Heidi Schlichting, Kerstin Skibbe, Mohab Ragab, Annika Raschdorf, Misa Hirose, Holger Schäffler, Arne Bokemeyer, Dominik Bettenworth, Anne G. Savitt, Sven Perner, Saleh Ibrahim, Ellinor I. Peerschke, Berhane Ghebrehiwet, Stefanie Derer, Christian Sina
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 1, Pp 229-250 (2021)
Background & Aims: Cell differentiation in the colonic crypt is driven by a metabolic switch from glycolysis to mitochondrial oxidation. Mitochondrial and goblet cell dysfunction have been attributed to the pathology of ulcerative colitis (UC). We hy
Externí odkaz:
https://doaj.org/article/3c9778069d6f49cc96087014960b017d
Autor:
Julien Pothlichet, Annalisa Meola, Florence Bugault, Louise Jeammet, Anne G. Savitt, Berhane Ghebrehiwet, Lhousseine Touqui, Philippe Pouletty, Frédéric Fiore, Alain Sauvanet, Jacques Thèze
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The origin of the impaired CD4 T-cell response and immunodeficiency of HIV-infected patients is still only partially understood. We recently demonstrated that PLA2G1B phospholipase synergizes with the HIV gp41 envelope protein in HIV viremic plasma t
Externí odkaz:
https://doaj.org/article/b03bd2678ba64c0090485102c4cbf5f9
Autor:
Vanessa K. A. Silva, Somanon Bhattacharya, Natalia Kronbauer Oliveira, Anne G. Savitt, Daniel Zamith-Miranda, Joshua D. Nosanchuk, Bettina C. Fries
Publikováno v:
mBio, Vol 13, Iss 1 (2022)
ABSTRACT Replicative aging is an underexplored field of research in medical mycology. Cryptococcus neoformans (Cn) and Candida glabrata (Cg) are dreaded fungal pathogens that cause fatal invasive infections. The fungal cell wall is essential for yeas
Externí odkaz:
https://doaj.org/article/254adcc416374002bd625ca8e9cbf4bb
Autor:
Anne G. Savitt, Samantha Manimala, Tiara White, Marina Fandaros, Wei Yin, Huiquan Duan, Xin Xu, Brian V. Geisbrecht, David A. Rubenstein, Allen P. Kaplan, Ellinor I. Peerschke, Berhane Ghebrehiwet
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Infection with SARS-CoV-2 triggers the simultaneous activation of innate inflammatory pathways including the complement system and the kallikrein-kinin system (KKS) generating in the process potent vasoactive peptides that contribute to severe acute
Externí odkaz:
https://doaj.org/article/6770e2f74e8948b8a62d2b8fa28fe7c4
Autor:
Dennis K. Galanakis, Anna Protopopova, Liudi Zhang, Kao Li, Clement Marmorat, Tomas Scheiner, Jaseung Koo, Anne G. Savitt, Miriam Rafailovich, John Weisel
Publikováno v:
TH Open, Vol 05, Iss 03, Pp e273-e285 (2021)
Objective Soluble fibrin (SF) is a substantial component of plasma fibrinogen (fg), but its composition, functions, and clinical relevance remain unclear. The study aimed to evaluate the molecular composition and procoagulant function(s) of SF. Mater
Externí odkaz:
https://doaj.org/article/3586f8fcaa7141abaab9d03888eab6a8
Autor:
Somanon Bhattacharya, Natalia Kronbauer Oliveira, Anne G. Savitt, Vanessa K. A. Silva, Rachel B. Krausert, Berhane Ghebrehiwet, Bettina C. Fries
Publikováno v:
Journal of Fungi, Vol 7, Iss 6, p 489 (2021)
Chronic meningoencephalitis is caused by Cryptococcus neoformans and is treated in many parts of the world with fluconazole (FLC) monotherapy, which is associated with treatment failure and poor outcome. In the host, C. neoformans propagates predomin
Externí odkaz:
https://doaj.org/article/666f46a3ccc649e7af43f5a2f05ed2bb
Autor:
Ellinor I. Peerschke, Elisa de Stanchina, Qing Chang, Katia Manova-Todorova, Afsar Barlas, Anne G. Savitt, Brian V. Geisbrecht, Berhane Ghebrehiwet
Publikováno v:
Antibodies, Vol 9, Iss 4, p 51 (2020)
gC1qR is highly expressed in breast cancer and plays a role in cancer cell proliferation. This study explored therapy with gC1qR monoclonal antibody 60.11, directed against the C1q binding domain of gC1qR, in a murine orthotopic xenotransplant model
Externí odkaz:
https://doaj.org/article/b3bfd026ac4f49ce814d26f8b134bf75
Autor:
Anna D. Protopopova, Dennis K. Galanakis, Anne G. Savitt, John W. Weisel, Clement Marmorat, Kao Li, Tomas Scheiner, Liudi Zhang, Jaseung Koo, Miriam Rafailovich
Publikováno v:
TH Open: Companion Journal to Thrombosis and Haemostasis
TH Open, Vol 05, Iss 03, Pp e273-e285 (2021)
TH Open, Vol 05, Iss 03, Pp e273-e285 (2021)
Objective Soluble fibrin (SF) is a substantial component of plasma fibrinogen (fg), but its composition, functions, and clinical relevance remain unclear. The study aimed to evaluate the molecular composition and procoagulant function(s) of SF. Mater
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::671217e38d7656ec49cb0d71a3883f6a
http://europepmc.org/articles/PMC8260279
http://europepmc.org/articles/PMC8260279
Autor:
Vanessa K.A. Silva, Somanon Bhattacharya, Natalia Kronbauer Oliveira, Anne G. Savitt, Daniel Zamith-Miranda, Joshua D. Nosanchuk, Bettina C. Fries
Replicative aging is an underexplored field of research in medical mycology. Cryptococcus neoformans (Cn) and Candida glabrata (Cg) are dreaded fungal pathogens that cause fatal invasive infections. The fungal cell wall is essential for yeast viabili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b3beb72e8476dc29ee03384dc78590bf
https://doi.org/10.1101/2022.01.25.477803
https://doi.org/10.1101/2022.01.25.477803
