Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Anne Flament"'
Autor:
Thủy Nguyễn, Caroline Lonez, Eytan Breman, Fanny Huberty, Celine Jacques-Hespel, Anne Flament, Jennifer Bolsee, Benjamin Demoulin
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/1d1643df61a147c982e23ae86ed284e1
Autor:
David Gilham, Caroline Lonez, Anne Flament, Frédéric Lehmann, Erik Alcantar-Orozco, Emilie Cerf, Charles Morris
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/5abb03e9bf154957a7c05352f8a771ee
Autor:
David A Sallman, Tessa Kerre, Violaine Havelange, Xavier Poiré, Philippe Lewalle, Eunice S Wang, Jason B Brayer, Marco L Davila, Ine Moors, Jean-Pascal Machiels, Ahmad Awada, Erik M Alcantar-Orozco, Rossitza Borissova, Nathalie Braun, Marie-Sophie Dheur, David E Gilham, Caroline Lonez, Frédéric F Lehmann, Anne Flament
Publikováno v:
The Lancet Haematology. 10:e191-e202
Autor:
Caroline Lonez, Ahmad-Samer Al-Homsi, Dries Deeren, Nathalie Meuleman, Anne Flament, David E. Gilham, Taiga Nishihori, Marie-Sophie Dheur, Maher Abdul-Hay, Nathalie Braun, Erik Alcantar-Orozco, Gareth J. Morgan, Sébastien Anguille, Jason Brayer, Frederic Lehmann
Publikováno v:
Blood. 138:2817-2817
Off-the-shelf allogeneic CAR T cells derived from healthy donor cells have the potential to overcome many of the issues associated with the time-consuming manufacturing of autologous CAR T cells. However, adoptive transfer of allogeneic T cells carri
Autor:
Yves Beguin, David E. Gilham, Erik Alcantar-Orozco, Anne Flament, Caroline Lonez, Dries Deeren, Tara L. Lin, Nathalie Braun, Frederic Lehmann, Eytan Breman, Johan Maertens, Marie-Sophie Dheur
Publikováno v:
Blood. 138:408-408
While CAR T cell therapy has delivered impressive clinical efficacy in B cell malignancies, similar levels of clinical activity have not been demonstrated in acute myeloid leukemia (AML). One underlying reason for this lack of translation is the rela
Autor:
Frederic Lehmann, Caroline Lonez, Charles Morris, Anne Flament, David E. Gilham, Emilie Cerf, Erik Alcantar-Orozco
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
BackgroundThe peptide-based allogeneic chimeric antigen receptor (CAR) T-cell treatment CYAD-101 utilizes an NKG2D receptor that targets eight ligands expressed on tumor cells and non-malignant stromal cells of many cancer types. CYAD-101 also co-exp
Autor:
Marc Van den Eynde, Alain Hendlisz, Hans Prenen, Mateusz Opyrchal, Javier Carrasco, Jean-Luc Canon, Lorraine Springuel, Frederic Lehmann, Caroline Lonez, Anne Flament, Jean-Pascal Machiels, Sylvie Rottey, David E. Gilham, Kunle Odunsi, Leila Shaza, Eric Van Cutsem, Bertrand Alexandre
Publikováno v:
BIODRUGS
BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy, Vol. 33, no. 5, p. 515-537 (2019)
Biodrugs
BioDrugs
BioDrugs, Vol. 33, no. 5, p. 515-537 (2019)
BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy, Vol. 33, no. 5, p. 515-537 (2019)
Biodrugs
BioDrugs
BioDrugs, Vol. 33, no. 5, p. 515-537 (2019)
Chimeric antigen receptor-T cells (CAR-Ts) are an exciting new cancer treatment modality exemplified by the recent regulatory approval of two CD19-targeted CAR-T therapies for certain B cell malignancies. However, this success in the hematological se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81d4b739c3db93b42e03d57d5d8542f7
https://lirias.kuleuven.be/handle/123456789/641740
https://lirias.kuleuven.be/handle/123456789/641740
Publikováno v:
Annals of Hematology
Although immunomodulatory drugs, alkylating agents, corticosteroids, protease inhibitors, and therapeutic monoclonal antibodies improve multiple myeloma outcomes, treatment burden is still an issue. Neutropenia is a known complication of cytotoxic ca
Autor:
A. Samer Al-Homsi, Marie-Sophie Dheur, Nathalie Braun, Daniel A. Pollyea, David A. Sallman, Ine Moors, David E. Gilham, Anne Flament, William Blum, Frederic Lehmann, Erik Alcantar-Orozco, Philippe Lewalle, Caroline Lonez, Eytan Breman, Violaine Havelange, Marco L. Davila, Tessa Kerre, Xavier Poiré, Panagiota A. Sotiropoulou, Eunice S. Wang, Benjamin Demoulin
Publikováno v:
Blood. 136:40-41
Background CYAD-01 is a T-cell product engineered to express a chimeric antigen receptor (CAR) based on the NKG2D receptor (NKG2D CAR) which binds 8 ligands (MICA/B, ULBP1-6) over-expressed by a large variety of malignancies, including acute myeloid
Autor:
Panagiota A. Sotiropoulou, Frederic Lehmann, Laure Twyffels, Nathalie Meuleman, Anne Flament, Dries Deeren, Caroline Lonez, Nathalie Braun, Jason Brayer, Gareth J. Morgan, David E. Gilham, Taiga Nishihori, A. Samer Al-Homsi, Sébastien Anguille, Jennifer Bolsée
Publikováno v:
Blood. 136:27-28
Background Autologous CAR T-cell therapy targeting the B-cell maturation antigen (BCMA) has shown impressive objective response rates in patients with advanced multiple myeloma (MM). Clinical grade manufacturing of autologous CAR T-cells has limitati