Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Anne Fåne"'
Autor:
Nadia Mensali, Hakan Köksal, Sandy Joaquina, Patrik Wernhoff, Nicholas P. Casey, Paola Romecin, Carla Panisello, René Rodriguez, Lene Vimeux, Asta Juzeniene, Marit R. Myhre, Anne Fåne, Carolina Castilla Ramírez, Solrun Melkorka Maggadottir, Adil Doganay Duru, Anna-Maria Georgoudaki, Iwona Grad, Andrés Daniel Maturana, Gustav Gaudernack, Gunnar Kvalheim, Angel M. Carcaboso, Enrique de Alava, Emmanuel Donnadieu, Øyvind S. Bruland, Pablo Menendez, Else Marit Inderberg, Sébastien Wälchli
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Osteosarcoma (OS) remains a dismal malignancy in children and young adults, with poor outcome for metastatic and recurrent disease. Immunotherapies in OS are not as promising as in some other cancer types due to intra-tumor heterogeneity and
Externí odkaz:
https://doaj.org/article/aeb35d7698f54300a9d32846913690b0
Autor:
Nadia Mensali, Pierre Dillard, Michael Hebeisen, Susanne Lorenz, Theodossis Theodossiou, Marit Renée Myhre, Anne Fåne, Gustav Gaudernack, Gunnar Kvalheim, June Helen Myklebust, Else Marit Inderberg, Sébastien Wälchli
Publikováno v:
EBioMedicine, Vol 40, Iss , Pp 106-117 (2019)
Background: Adoptive T-cell transfer of therapeutic TCR holds great promise to specifically kill cancer cells, but relies on modifying the patient's own T cells ex vivo before injection. The manufacturing of T cells in a tailor-made setting is a long
Externí odkaz:
https://doaj.org/article/baa96d23750c455aa947c1f06061880a
Autor:
Even Walseng, Hakan Köksal, Ibrahim M. Sektioglu, Anne Fåne, Gjertrud Skorstad, Gunnar Kvalheim, Gustav Gaudernack, Else Marit Inderberg, Sébastien Wälchli
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract Effector T cells equipped with engineered antigen receptors specific for cancer targets have proven to be very efficient. Two methods have emerged: the Chimeric Antigen Receptors (CARs) and T-cell Receptor (TCR) redirection. Although very po
Externí odkaz:
https://doaj.org/article/0e8a6236e1d04796a5c036d02bcd1d20
Publikováno v:
OncoImmunology, Vol 8, Iss 4 (2019)
Adoptive cell therapy (ACT) with retargeted T cells has produced remarkable clinical responses against cancer, but also serious toxicity. Telomerase is overexpressed in most cancers, but also expressed in some normal cells, raising safety concerns. W
Externí odkaz:
https://doaj.org/article/0f3fa1a201b24142b902978565ba5d00
Autor:
Mensali, Nadia, Köksal, Hakan, Joaquina, Sandy, Vernhoff, Håkan Patrik, Casey, Nicholas Paul, Romecin, Paola, Panisello, Carla, Rodriguez, René, Vimeux, Lene, Juzenienne, Asta, Myhre, Marit Renee, Bøthun, Anne Fåne, Ramírez, Carolina Castilla, Maggadottir, Solrun Melkorka, Duru, Adil Doganay, Georgoudaki, Anna-Maria, Grad, Iwona, Maturana, Andrés Daniel, Gaudernack, Gustav, Kvalheim, Gunnar, Carcaboso, Angel M., de Alava, Enrique, Donnadieu, Emmanuel, Bruland, Øyvind, Menendez, Pablo, Inderberg, Else Marit, Wälchli, Sébastien
Publikováno v:
Mensali, Nadia Köksal, Hakan Joaquina, Sandy Vernhoff, Håkan Patrik Casey, Nicholas Paul Romecin, Paola Panisello, Carla Rodriguez, René Vimeux, Lene Juzenienne, Asta Myhre, Marit Renee Bøthun, Anne Fåne Ramírez, Carolina Castilla Maggadottir, Solrun Melkorka Duru, Adil Doganay Georgoudaki, Anna-Maria Grad, Iwona Maturana, Andrés Daniel Gaudernack, Gustav Kvalheim, Gunnar Carcaboso, Angel M. de Alava, Enrique Donnadieu, Emmanuel Bruland, Øyvind Menendez, Pablo Inderberg, Else Marit Wälchli, Sébastien . ALPL-1 is a target for chimeric antigen receptor therapy in osteosarcoma. Nature Communications. 2023, 14
Nature Communications
Nature Communications
Externí odkaz:
http://hdl.handle.net/10852/107419
Autor:
Casey, Nicholas Paul, Klee, Clara Helena, Bøthun, Anne Fåne, Caulier, Benjamin William, Graczyk-Jarzynka, Agnieszka, Krawczyk, Marta, Fidyt, Klaudyna, Josefsson, Sarah Elisabet, Köksal, Hakan, Dillard, Pierre, Patkowska, Elzbieta, Firczuk, Malgorzata, Smeland, Erlend Bremertun, Winiarska, Magdalena, Myklebust, June Helen, Inderberg, Else Marit, Wälchli, Sébastien
Publikováno v:
Casey, Nicholas Paul Klee, Clara Helena Bøthun, Anne Fåne Caulier, Benjamin William Graczyk-Jarzynka, Agnieszka Krawczyk, Marta Fidyt, Klaudyna Josefsson, Sarah Elisabet Köksal, Hakan Dillard, Pierre Patkowska, Elzbieta Firczuk, Malgorzata Smeland, Erlend Bremertun Winiarska, Magdalena Myklebust, June Helen Inderberg, Else Marit Wälchli, Sébastien . Efficient chimeric antigen receptor targeting of a central epitope of CD22. Jo
Jo
Jo
Externí odkaz:
http://hdl.handle.net/10852/107210
Publikováno v:
Methods in cell biology. 167
Pre-clinical evaluation of CAR T cells includes procedures testing T-cell efficacy and safety in as close to real world conditions as possible. An important step in efficacy testing is the in vivo study, most often using immunodeficient murine models
Publikováno v:
Methods in Cell Biology ISBN: 9780323855013
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db872ec0f1404415514490be6207837f
https://doi.org/10.1016/bs.mcb.2021.11.001
https://doi.org/10.1016/bs.mcb.2021.11.001
Autor:
June Helen Myklebust, Sébastien Wälchli, Are Kolstad, Yngvild Nuvin Blaker, Solrun Melkorka Maggadottir, Sarah Elisabet Josefsson, Kanutte Huse, Pierre Dillard, Gunnar Kvalheim, Hakan Köksal, Else Marit Inderberg, Anne Fåne, Harald Holte, Sylvie Pollmann, Erlend B. Smeland, Klaus Beiske
Publikováno v:
Blood Advances. 3:1230-1243
T cells modified to express chimeric antigen receptor (CAR) targeting CD19 (CD19CAR) have produced remarkable clinical responses in patients with relapsed/refractory B-cell acute lymphoblastic leukemia. CD19CAR T-cell therapy has also demonstrated pr
Autor:
June Helen Myklebust, Oddmund Bakke, Grethe Elisabeth Stenvik, Nadia Mensali, Lars Egil Fallang, Cinzia Progida, Anne Fåne, Gunnar Kvalheim, Gjertrud Skorstad, Else Marit Inderberg, Sébastien Wälchli, Morten P. Oksvold
Publikováno v:
Cancer Immunology, Immunotherapy. 67:525-536
Adoptive cell therapy with T-cell receptor (TCR)-engineered T cells represents a powerful method to redirect the immune system against tumours. However, although TCR recognition is restricted to a specific peptide-MHC (pMHC) complex, increasing numbe