Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Anne Eugster"'
Autor:
Anne Eugster, Anna Lorenc, Martin Kotrulev, Yogesh Kamra, Manisha Goel, Katja Steinberg-Bains, Shereen Sabbah, Sevina Dietz, Ezio Bonifacio, Mark Peakman, Iria Gomez-Tourino
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Autoimmune diseases result from autoantigen-mediated activation of adaptive immunity; intriguingly, autoantigen-specific T cells are also present in healthy donors. An assessment of dynamic changes of this autoreactive repertoire in both hea
Externí odkaz:
https://doaj.org/article/232b3f7f7b544729b1e9d70d032e0c11
Autor:
Anne Eugster, Denise Müller, Anne Gompf, Susanne Reinhardt, Annett Lindner, Michelle Ashton, Nick Zimmermann, Stefan Beissert, Ezio Bonifacio, Claudia Günther
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/7203cfb05b9f4baeb29fa431d030cfb6
Autor:
Anne Eugster, Denise Müller, Anne Gompf, Susanne Reinhardt, Annett Lindner, Michelle Ashton, Nick Zimmermann, Stefan Beissert, Ezio Bonifacio, Claudia Günther
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Heterozygous TREX1 mutations are associated with monogenic familial chilblain lupus and represent a risk factor for developing systemic lupus erythematosus. These interferonopathies originate from chronic type I interferon stimulation due to sensing
Externí odkaz:
https://doaj.org/article/817b4a005bfd4d63a3713bff11c81cea
Autor:
Johannes Trück, Anne Eugster, Pierre Barennes, Christopher M Tipton, Eline T Luning Prak, Davide Bagnara, Cinque Soto, Jacob S Sherkow, Aimee S Payne, Marie-Paule Lefranc, Andrew Farmer, The AIRR Community, Magnolia Bostick, Encarnita Mariotti-Ferrandiz
Publikováno v:
eLife, Vol 10 (2021)
Use of adaptive immune receptor repertoire sequencing (AIRR-seq) has become widespread, providing new insights into the immune system with potential broad clinical and diagnostic applications. However, like many high-throughput technologies, it comes
Externí odkaz:
https://doaj.org/article/818c2fca5da7403ca21771e78fa6a176
Autor:
Tatyana Grinenko, Anne Eugster, Lars Thielecke, Beáta Ramasz, Anja Krüger, Sevina Dietz, Ingmar Glauche, Alexander Gerbaulet, Malte von Bonin, Onur Basak, Hans Clevers, Triantafyllos Chavakis, Ben Wielockx
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Dependence of hematopoietic stem cell (HSC) fate on the phase of the cell cycle has not been demonstrated in vivo. Here, the authors find that HSCs can differentiate into a downstream progenitor without physical division, even before progressing into
Externí odkaz:
https://doaj.org/article/681a9eaa5b95419b80609eae18b557be
Autor:
Sumeet Pal Singh, Sharan Janjuha, Theresa Hartmann, Özge Kayisoglu, Judith Konantz, Sarah Birke, Priyanka Murawala, Ezzaldin Ahmed Alfar, Kei Murata, Anne Eugster, Naoki Tsuji, Edward R. Morrissey, Michael Brand, Nikolay Ninov
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
Βeta-cells have recently been shown to be heterogeneous with regard to morphology and function. Here, the authors show that β-cells in zebrafish switch from proliferative to functional states with increasing time since β-cell birth, leading to fun
Externí odkaz:
https://doaj.org/article/09d63bb2e4484ac98df9ddecef7e0e11
Autor:
Yannick F. Fuchs, Virag Sharma, Anne Eugster, Gloria Kraus, Robert Morgenstern, Andreas Dahl, Susanne Reinhardt, Andreas Petzold, Annett Lindner, Doreen Löbel, Ezio Bonifacio
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
CD8+ T cells are important effectors of adaptive immunity against pathogens, tumors, and self antigens. Here, we asked how human cognate antigen-responsive CD8+ T cells and their receptors could be identified in unselected single-cell gene expression
Externí odkaz:
https://doaj.org/article/d40caab940694d05ab121ac4096494be
Autor:
Cornelia S. Link-Rachner, Anne Eugster, Elke Rücker-Braun, Falk Heidenreich, Uta Oelschlägel, Andreas Dahl, Christian Klesse, Matthias Kuhn, Jan Moritz Middeke, Martin Bornhäuser, Ezio Bonifacio, Johannes Schetelig
Publikováno v:
Haematologica, Vol 104, Iss 3 (2019)
Alloreactivity or opportunistic infections following allogeneic stem cell transplantation are difficult to predict and contribute to post-transplantation mortality. How these immune reactions result in changes to the T-cell receptor repertoire remain
Externí odkaz:
https://doaj.org/article/92e0ce6b2ae34144ad4705cb523e49b9
Autor:
Falk Heidenreich, Elke Rücker-Braun, Juliane S. Walz, Anne Eugster, Denise Kühn, Sevina Dietz, Annika Nelde, Antje Tunger, Rebekka Wehner, Cornelia S. Link, Jan M. Middeke, Friedrich Stölzel, Torsten Tonn, Stefan Stevanovic, Hans-Georg Rammensee, Ezio Bonifacio, Michael Bachmann, Matthias Zeis, Gerhard Ehninger, Martin Bornhäuser, Johannes Schetelig, Marc Schmitz
Publikováno v:
Haematologica, Vol 102, Iss 11 (2017)
Externí odkaz:
https://doaj.org/article/176e4e3303e44d22aec608b09d162794
Autor:
Manisha Goel, Anne Eugster, Johannes Schetelig, Ezio Bonifacio, Martin Bornhäuser, Cornelia S. Link-Rachner
Publikováno v:
Bone Marrow Transplantation. 58:239-246
Graft-versus-host disease (GvHD) remains one of the major complications following allogeneic haematopoietic stem cell transplantation (allo-HSCT). GvHD can occur in almost every tissue, with the skin, liver, and intestines being the mainly affected o