Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Anne Engesser"'
Autor:
Carolina Rosswog, Rene Schmidt, André Oberthuer, Dilafruz Juraeva, Benedikt Brors, Anne Engesser, Yvonne Kahlert, Ruth Volland, Christoph Bartenhagen, Thorsten Simon, Frank Berthold, Barbara Hero, Andreas Faldum, Matthias Fischer
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 19, Iss 12, Pp 982-990 (2017)
BACKGROUND: Current risk stratification systems for neuroblastoma patients consider clinical, histopathological, and genetic variables, and additional prognostic markers have been proposed in recent years. We here sought to select highly informative
Externí odkaz:
https://doaj.org/article/c6f0641f7ed243fea6fcc8ab5e4a9724
Autor:
Matthias Fischer, Benedikt Brors, Frank Westermann, Frank Berthold, Jessica Theissen, Thorsten Simon, Roland Eils, Manfred Schwab, Chunxuan Shao, Monika Ortmann, Richard G. Grundy, Isaac Yaniv, Smadar Avigad, Alexander Valent, Jean Bénard, Marta Piqueras, Rosa Noguera, Frank Speleman, Jo Vandesompele, Gudrun Schleiermacher, Olivier Delattre, Isabelle Janoueix-Lerosey, Gian Paolo Tonini, Paola Scaruffi, Akira Nakagawara, Miki Ohira, Robert Seeger, Shahab Asgharzadeh, Anne Engesser, Yvonne Kahlert, Andreas Faldum, Rene Schmidt, Carolina Sterz, Ruth Volland, Barbara Hero, Dilafruz Juraeva, André Oberthuer
Supplementary Data 1. This supplementary data comprises a step-by-step description on how our gene-expression based classification models were generated and validated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::775a6802982592c68b0660667a5e03e7
https://doi.org/10.1158/1078-0432.22455450.v1
https://doi.org/10.1158/1078-0432.22455450.v1
Autor:
Matthias Fischer, Benedikt Brors, Frank Westermann, Frank Berthold, Jessica Theissen, Thorsten Simon, Roland Eils, Manfred Schwab, Chunxuan Shao, Monika Ortmann, Richard G. Grundy, Isaac Yaniv, Smadar Avigad, Alexander Valent, Jean Bénard, Marta Piqueras, Rosa Noguera, Frank Speleman, Jo Vandesompele, Gudrun Schleiermacher, Olivier Delattre, Isabelle Janoueix-Lerosey, Gian Paolo Tonini, Paola Scaruffi, Akira Nakagawara, Miki Ohira, Robert Seeger, Shahab Asgharzadeh, Anne Engesser, Yvonne Kahlert, Andreas Faldum, Rene Schmidt, Carolina Sterz, Ruth Volland, Barbara Hero, Dilafruz Juraeva, André Oberthuer
Supplementary Figure 1. Highlights the EFS and OS for the cohort of neuroblastoma patients with MYCN-amplified disease (n=114, Fig 1a) and for th subcohort of patients >18 months of age with stage 4, MYCN non-amplified disease (n=102, fig. 1b). F, fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c228f0350bfef9c250b0ac38eb3771c9
https://doi.org/10.1158/1078-0432.22455444
https://doi.org/10.1158/1078-0432.22455444
Autor:
Matthias Fischer, Benedikt Brors, Frank Westermann, Frank Berthold, Jessica Theissen, Thorsten Simon, Roland Eils, Manfred Schwab, Chunxuan Shao, Monika Ortmann, Richard G. Grundy, Isaac Yaniv, Smadar Avigad, Alexander Valent, Jean Bénard, Marta Piqueras, Rosa Noguera, Frank Speleman, Jo Vandesompele, Gudrun Schleiermacher, Olivier Delattre, Isabelle Janoueix-Lerosey, Gian Paolo Tonini, Paola Scaruffi, Akira Nakagawara, Miki Ohira, Robert Seeger, Shahab Asgharzadeh, Anne Engesser, Yvonne Kahlert, Andreas Faldum, Rene Schmidt, Carolina Sterz, Ruth Volland, Barbara Hero, Dilafruz Juraeva, André Oberthuer
Purpose: To optimize neuroblastoma treatment stratification, we aimed at developing a novel risk estimation system by integrating gene expression–based classification and established prognostic markers.Experimental Design: Gene expression profiles
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ca2b97b271ac1b8d0f69094ec95fac3
https://doi.org/10.1158/1078-0432.c.6523032
https://doi.org/10.1158/1078-0432.c.6523032
Autor:
Matthias Fischer, Benedikt Brors, Frank Westermann, Frank Berthold, Jessica Theissen, Thorsten Simon, Roland Eils, Manfred Schwab, Chunxuan Shao, Monika Ortmann, Richard G. Grundy, Isaac Yaniv, Smadar Avigad, Alexander Valent, Jean Bénard, Marta Piqueras, Rosa Noguera, Frank Speleman, Jo Vandesompele, Gudrun Schleiermacher, Olivier Delattre, Isabelle Janoueix-Lerosey, Gian Paolo Tonini, Paola Scaruffi, Akira Nakagawara, Miki Ohira, Robert Seeger, Shahab Asgharzadeh, Anne Engesser, Yvonne Kahlert, Andreas Faldum, Rene Schmidt, Carolina Sterz, Ruth Volland, Barbara Hero, Dilafruz Juraeva, André Oberthuer
Supplementary Table 1. Clinical co-variates for the 709 patients who participated in the study. This supplementary table comprises detailed information on clinical co-variates for all 709 neuroblastoma patients who participated in the study.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36153a937748ade2c45687cdfbb21a46
https://doi.org/10.1158/1078-0432.22455441
https://doi.org/10.1158/1078-0432.22455441
Autor:
Matthias Fischer, Benedikt Brors, Frank Westermann, Frank Berthold, Jessica Theissen, Thorsten Simon, Roland Eils, Manfred Schwab, Chunxuan Shao, Monika Ortmann, Richard G. Grundy, Isaac Yaniv, Smadar Avigad, Alexander Valent, Jean Bénard, Marta Piqueras, Rosa Noguera, Frank Speleman, Jo Vandesompele, Gudrun Schleiermacher, Olivier Delattre, Isabelle Janoueix-Lerosey, Gian Paolo Tonini, Paola Scaruffi, Akira Nakagawara, Miki Ohira, Robert Seeger, Shahab Asgharzadeh, Anne Engesser, Yvonne Kahlert, Andreas Faldum, Rene Schmidt, Carolina Sterz, Ruth Volland, Barbara Hero, Dilafruz Juraeva, André Oberthuer
Supplementary Table 2. External performance validation of the top five classifiers. This supplementary table comprises the external performance metrics of the top five classifiers. Indicated are the values for classification accuracy, sensitivity , s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14843685e084ad1f63fc9e206b7f0fe1
https://doi.org/10.1158/1078-0432.22455438.v1
https://doi.org/10.1158/1078-0432.22455438.v1
Autor:
Matthias Fischer, Benedikt Brors, Frank Westermann, Frank Berthold, Jessica Theissen, Thorsten Simon, Roland Eils, Manfred Schwab, Chunxuan Shao, Monika Ortmann, Richard G. Grundy, Isaac Yaniv, Smadar Avigad, Alexander Valent, Jean Bénard, Marta Piqueras, Rosa Noguera, Frank Speleman, Jo Vandesompele, Gudrun Schleiermacher, Olivier Delattre, Isabelle Janoueix-Lerosey, Gian Paolo Tonini, Paola Scaruffi, Akira Nakagawara, Miki Ohira, Robert Seeger, Shahab Asgharzadeh, Anne Engesser, Yvonne Kahlert, Andreas Faldum, Rene Schmidt, Carolina Sterz, Ruth Volland, Barbara Hero, Dilafruz Juraeva, André Oberthuer
Supplementary Table 4. Transcripts that contribute to the SVM_th10 classifier. This supplementary table highlights the transcripts that constitute the SVM_th10 classifier. Indicated for each feature are the Oligo-ID, the Gene symbols, the Entrez gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3154b4da0a902e14ed5e7efd16d71ed7
https://doi.org/10.1158/1078-0432.22455432
https://doi.org/10.1158/1078-0432.22455432
Autor:
Matthias Fischer, Benedikt Brors, Frank Westermann, Frank Berthold, Jessica Theissen, Thorsten Simon, Roland Eils, Manfred Schwab, Chunxuan Shao, Monika Ortmann, Richard G. Grundy, Isaac Yaniv, Smadar Avigad, Alexander Valent, Jean Bénard, Marta Piqueras, Rosa Noguera, Frank Speleman, Jo Vandesompele, Gudrun Schleiermacher, Olivier Delattre, Isabelle Janoueix-Lerosey, Gian Paolo Tonini, Paola Scaruffi, Akira Nakagawara, Miki Ohira, Robert Seeger, Shahab Asgharzadeh, Anne Engesser, Yvonne Kahlert, Andreas Faldum, Rene Schmidt, Carolina Sterz, Ruth Volland, Barbara Hero, Dilafruz Juraeva, André Oberthuer
Legends to Supplementaries. This documents comprises the legends to the supplementary figures and tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b8889226c2fd7d4c21a33b67d5117ad
https://doi.org/10.1158/1078-0432.22455453
https://doi.org/10.1158/1078-0432.22455453
Autor:
Matthias Fischer, Benedikt Brors, Frank Westermann, Frank Berthold, Jessica Theissen, Thorsten Simon, Roland Eils, Manfred Schwab, Chunxuan Shao, Monika Ortmann, Richard G. Grundy, Isaac Yaniv, Smadar Avigad, Alexander Valent, Jean Bénard, Marta Piqueras, Rosa Noguera, Frank Speleman, Jo Vandesompele, Gudrun Schleiermacher, Olivier Delattre, Isabelle Janoueix-Lerosey, Gian Paolo Tonini, Paola Scaruffi, Akira Nakagawara, Miki Ohira, Robert Seeger, Shahab Asgharzadeh, Anne Engesser, Yvonne Kahlert, Andreas Faldum, Rene Schmidt, Carolina Sterz, Ruth Volland, Barbara Hero, Dilafruz Juraeva, André Oberthuer
Supplementary Data 2. This supplementary data comprises the r-algorithm scripts required to perform the both model selection and validation as described in the step-by-step protocol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4acf7afd97b71e73dc73f5d55b06605c
https://doi.org/10.1158/1078-0432.22455447.v1
https://doi.org/10.1158/1078-0432.22455447.v1
Autor:
Andreas Faldum, Rene Schmidt, Benedikt Brors, Yvonne Kahlert, Frank Berthold, Thorsten Simon, André Oberthuer, Ruth Volland, Matthias Fischer, Christoph Bartenhagen, Barbara Hero, Dilafruz Juraeva, Anne Engesser, Carolina Rosswog
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 19, Iss 12, Pp 982-990 (2017)
Neoplasia (New York, N.Y.)
Neoplasia (New York, N.Y.)
BACKGROUND: Current risk stratification systems for neuroblastoma patients consider clinical, histopathological, and genetic variables, and additional prognostic markers have been proposed in recent years. We here sought to select highly informative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f86d6639a620d3bfab8a5d2b57d85639
https://doi.org/10.1016/j.neo.2017.09.006
https://doi.org/10.1016/j.neo.2017.09.006