Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Anne Edenro"'
Autor:
Kenneth B. Jonsson, Harriet Andersén, Lijuan Hu, Thomas Lind, Håkan Melhus, Anne Edenro, Mohammad Bohlooly-Y
Publikováno v:
Journal of Bone and Mineral Metabolism. 30:304-311
ADAMTS1, a secreted multifunctional metalloproteinase with disintegrin and thrombospondin motifs, is an early response gene of parathyroid hormone (PTH) in osteoblasts. Mice engineered to lack Adamts1 are smaller compared to wild-type (WT) mice and A
Autor:
Annelie Lindqvist, Ylva Terelius, Anne Edenro, Susanne Löfgren, Masahiro Hiratsuka, Sarah C. Sim, Meint Schülke, R. Michael Baldwin, Anne Carlberg, Michael Snait, Magnus Ingelman-Sundberg, Ronny Fransson-Steen
Publikováno v:
Drug Metabolism and Disposition. 36:955-962
CYP2C19 is an important enzyme for human drug metabolism, and it also participates in the metabolism of endogenous substrates, whereas the CYP2C18 enzyme is not expressed in human liver despite high mRNA expression. Mice transgenic for the human CYP2
Autor:
Anna Karin Gerdin, Michael Snaith, Alaa Saad, Ronny Fransson-Steen, Meint Schuelke, Elisabeth Jensen Lundgren, Vikas V. Surve, Mohammad Bohlooly-Y, Sivert Bjurström, Anne Edenro, Mikael Bjursell, Jan Törnell, Anna-Lena Berg, Marie Jönsson, Maria Björkman
Publikováno v:
Biochemical and biophysical research communications. 349(2)
Using the mouse as a model organism in pharmaceutical research presents unique advantages as its physiology in many ways resembles the human physiology, it also has a relatively short generation time, low breeding and maintenance costs, and is availa