Výsledky vyhledávání - "Anne E. Wiktor"

Data from Association of HER2/ErbB2 Expression and Gene Amplification with Pathologic Features and Prognosis in Esophageal Adenocarcinomas

Autor: Frank A. Sinicrope, Robert B. Jenkins, Robert B. Diasio, Tsung-Teh Wu, Axel Grothey, Christopher A. Sattler, Maliha Khan, Anne E. Wiktor, William R. Sukov, Qian Shi, Harry H. Yoon

Purpose: We examined the frequency, tumor characteristics, and prognostic impact of HER2 protein expression and gene amplification in patients with curatively resected esophageal adenocarcinoma (EAC).Experimental Design: HER2 expression was analyzed

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dec9967d1363fee8d0978632042d1e1
https://doi.org/10.1158/1078-0432.c.6519704.v1

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Identification of Adenosquamous Carcinoma as a Rare Aggressive HER2-negative Subgroup of Esophageal/Gastroesophageal Junction Adenocarcinoma

Autor: William R. Sukov, Harry H. Yoon, Marie Holubek, Anne E. Wiktor, Tsung-Teh Wu, Robert B. Jenkins, Zhaohui Jin, Christopher A. Sattler

Publikováno v: American journal of clinical oncology. 42(2)

BACKGROUND: Our purpose was to evaluate the prognostic impact of pathologically-confirmed esophageal adenosquamous carcinoma (ASC) and its association with HER2 status and clinicopathologic characteristics. METHODS: Among 796 patients with esophageal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2258f83c130984124a4e0249186d06dc
https://pubmed.ncbi.nlm.nih.gov/30516569

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Central nervous system relapse in patients with untreated HER2-positive esophageal or gastroesophageal junction adenocarcinoma

Autor: Anne E. Wiktor, Harry H. Yoon, Mark A. Lewis, Robert B. Jenkins, Nathan R. Foster, Christopher A. Sattler, Maliha Khan, William R. Sukov, Tsung Teh Wu, Frank A. Sinicrope

Publikováno v: International Journal of Cancer. 139:1626-1631

Although HER2-positive breast cancers demonstrate a propensity for central nervous system (CNS) metastasis, it is unknown whether other HER2-positive tumors, including adenocarcinomas of the esophagus/gastroesophageal junction (EAC), share this chara

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1c0ed48ecb459683a185560b95aada74
https://doi.org/10.1002/ijc.30200

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Is It Time for a New Gold Standard? FISH vs Cytogenetics in AML DiagnosisThe Authors’ Reply

Autor: Richard D. Hammer, Mark R. Litzow, Curtis A. Hanson, Rong He, Daniel L. Van Dyke, Paul J. Kurtin, Anne E. Wiktor, Donald C. Doll, Rhett P. Ketterling, Lester J. Layfield, Kaaren K. Reichard, Matthew T. Howard

Publikováno v: American Journal of Clinical Pathology. 145:430-432

We read with interest the recent article by He et al1 comparing conventional karyotyping and fluorescence in situ hybridization (FISH) in acute myeloid leukemia (AML). While the authors clearly show no advantage to FISH when karyotyping is adequate a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::606716c2902b2386a3d9d4bab4d2e148
https://doi.org/10.1093/ajcp/aqw008

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Molecular cytogenetic analysis for TFE3 rearrangement in Xp11.2 renal cell carcinoma and alveolar soft part sarcoma: validation and clinical experience with 75 cases

Autor: Andre M. Oliveira, Jennelle C. Hodge, Patricia T. Greipp, Xiaoke Wang, Anne E. Wiktor, Kathryn E. Pearce

Publikováno v: Modern Pathology. 27:113-127

Renal cell carcinoma with TFE3 rearrangement at Xp11.2 is a distinct subtype manifesting an indolent clinical course in children, with recent reports suggesting a more aggressive entity in adults. This subtype is morphologically heterogeneous and can

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ddcffafb8f356b98c2d4c097001de06
https://doi.org/10.1038/modpathol.2013.83

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HER-2/neugene amplification in relation to expression of HER2 and HER3 proteins in patients with esophageal adenocarcinoma

Autor: Anne E. Wiktor, Christopher A. Sattler, Robert B. Diasio, Robert B. Jenkins, Tsung Teh Wu, William R. Sukov, Frank A. Sinicrope, Qian Shi, Harry H. Yoon

Publikováno v: Cancer. 120:415-424

BACKGROUND Human epidermal growth factor receptor 2 (HER2) is a therapeutic target in patients with esophageal adenocarcinoma (EAC), with gene amplification used as a selection criterion for treatment, although to the authors' knowledge the concordan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7a8e3b1c3143ee8a23046c2e8a15610f
https://doi.org/10.1002/cncr.28435

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Abstract PD02-05: Comparison of fluorescence in situ hybridization (FISH) and dual-ISH (D-ISH) in the determination of HER2 status

Autor: William R. Sukov, Aaron S. Mansfield, Ahmet Dogan, Anne E. Wiktor, FJ Walsh, Y Sakai, Robert B. Jenkins

Publikováno v: Cancer Research. 72:PD02-05

Introduction: The appropriate assessment of HER2 amplification status is critical to determining which patients should receive HER2-directed therapy. An alternative to FISH is D-ISH (Ventana Medical Systems Tucson, Arizona) which utilizes chromogenic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::406b4fcd4ac1eacb0313eec1f9600273
https://doi.org/10.1158/0008-5472.sabcs12-pd02-05

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