The Beginnings of Spanish Settlement in the El Paso District Anne E. Hughes

Autor: Hackett, Charles W.

Publikováno v: The Southwestern Historical Quarterly, 1914 Oct 01. 18(2), 222-225.

Externí odkaz: https://www.jstor.org/stable/30234638

Susceptibility to invasive meningococcal disease: polymorphism of complement system genes and Neisseria meningitidis factor H binding protein.

Autor: Declan T Bradley, Thomas W Bourke, Derek J Fairley, Raymond Borrow, Michael D Shields, Peter F Zipfel, Anne E Hughes

Publikováno v: PLoS ONE, Vol 10, Iss 3, p e0120757 (2015)

Neisseria meningitidis can cause severe infection in humans. Polymorphism of Complement Factor H (CFH) is associated with altered risk of invasive meningococcal disease (IMD). We aimed to find whether polymorphism of other complement genes altered ri

Externí odkaz: https://doaj.org/article/a132c76cb3814764850efb788597a855

Deletion of complement factor H-related genes CFHR1 and CFHR3 is associated with atypical hemolytic uremic syndrome.

Autor: Peter F Zipfel, Matthew Edey, Stefan Heinen, Mihály Józsi, Heiko Richter, Joachim Misselwitz, Bernd Hoppe, Danny Routledge, Lisa Strain, Anne E Hughes, Judith A Goodship, Christoph Licht, Timothy H J Goodship, Christine Skerka

Publikováno v: PLoS Genetics, Vol 3, Iss 3, p e41 (2007)

Atypical hemolytic uremic syndrome (aHUS) is associated with defective complement regulation. Disease-associated mutations have been described in the genes encoding the complement regulators complement factor H, membrane cofactor protein, factor B, a

Externí odkaz: https://doaj.org/article/5dbab60a997e4d30ae0bf040891b6ada

Sequence and expression of complement factor H gene cluster variants and their roles in age-related macular degeneration risk

Autor: Weihua Meng, Declan Bradley, Dwight Stambolian, Mingyao Li, Christine A. Curcio, Anne E. Hughes, Stephen Bridgett

Publikováno v: Hughes, A E, Bridgett, S, Meng, W, Li, M, Curcio, C A, Stambolian, D & Bradley, D T 2016, ' Sequence and expression of complement factor H gene cluster variants and their roles in age-related macular degeneration risk ', Investigative Ophthalmology and Visual Science, vol. 57, no. 6, pp. 2763-2769 . https://doi.org/10.1167/iovs.15-18744
Investigative Ophthalmology & Visual Science

Purpose: To investigate how potentially functional genetic variants are coinherited on each of four common complement factor H (CFH) and CFH-related gene haplotypes and to measure expression of these genes in eye and liver tissues.Methods: We sequenc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40c3b7681322c91ba559cd18028193dc
https://pure.qub.ac.uk/en/publications/sequence-and-expression-of-complement-factor-h-gene-cluster-variants-and-their-roles-in-agerelated-macular-degeneration-risk(83356758-1280-4a78-90e3-fb43285c72f0).html

Complement in age-related macular degeneration: a focus on function

Autor: Anne E. Hughes, Declan Bradley, Peter F. Zipfel

Publikováno v: Eye. 25:683-693

Age-related macular degeneration (AMD) is an inflammatory disease, which causes visual impairment and blindness in older people. The proteins of the complement system are central to the development of this disease. Local and systemic inflammation in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0efb1eb4fd87f736cb7da1b419a7a728
https://doi.org/10.1038/eye.2011.37