Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Anne E. Geller"'
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-3 (2023)
Externí odkaz:
https://doaj.org/article/72630e2c24d1463ab4ab1a3d73d05aee
Autor:
Anne E. Geller, Rejeena Shrestha, Matthew R. Woeste, Haixun Guo, Xiaoling Hu, Chuanlin Ding, Kalina Andreeva, Julia H. Chariker, Mingqian Zhou, David Tieri, Corey T. Watson, Robert A. Mitchell, Huang-ge Zhang, Yan Li, Robert C. G. Martin II, Eric C. Rouchka, Jun Yan
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
The advent of immunotherapy has revolutionised cancer therapeutics, but its application in the context of pancreatic ductal adenocarcinoma has been limited. Here authors explore the effect of innate trained responses to fungal β-glucan and assess it
Externí odkaz:
https://doaj.org/article/60896ee968874b53b16e34db9dd843ba
Autor:
Samantha M. Morrissey, Anne E. Geller, Xiaoling Hu, David Tieri, Chuanlin Ding, Christopher K. Klaes, Elizabeth A. Cooke, Matthew R. Woeste, Zachary C. Martin, Oscar Chen, Sarah E. Bush, Huang-ge Zhang, Rodrigo Cavallazzi, Sean P. Clifford, James Chen, Smita Ghare, Shirish S. Barve, Lu Cai, Maiying Kong, Eric C. Rouchka, Kenneth R. McLeish, Silvia M. Uriarte, Corey T. Watson, Jiapeng Huang, Jun Yan
Publikováno v:
JCI Insight, Vol 6, Iss 9 (2021)
SARS coronavirus 2 (SARS-CoV-2) is a novel viral pathogen that causes a clinical disease called coronavirus disease 2019 (COVID-19). Although most COVID-19 cases are asymptomatic or involve mild upper respiratory tract symptoms, a significant number
Externí odkaz:
https://doaj.org/article/cd228fc8771e4fcab54acb1172e0ffbe
Publikováno v:
Cellular & Molecular Immunology. 19:1330-1332
Autor:
Matthew R Woeste, Rejeena Shrestha, Anne E Geller, Shu Li, Diego Montoya-Durango, Chuanlin Ding, Xiaoling Hu, Hong Li, Aaron Puckett, Robert A Mitchell, Traci Hayat, Min Tan, Yan Li, Kelly M McMasters, Robert C G Martin, Jun Yan
Publikováno v:
Journal for ImmunoTherapy of Cancer. 11:e006221
BackgroundPancreatic cancer (PC) is a challenging diagnosis that is yet to benefit from the advancements in immuno-oncologic treatments. Irreversible electroporation (IRE), a non-thermal method of tumor ablation, is used in treatment of select patien
Publikováno v:
Annals of Surgical Oncology. 28:1499-1510
Hepatocellular carcinoma (HCC), the most common primary hepatic malignancy worldwide, is the second leading cause of cancer-related death. Underlying liver dysfunction and advanced stage of disease require treatments to be optimally timed and impleme
Autor:
Harriet Eldridge-Hindy, Kelly M. McMasters, Nicolas Ajkay, Matthew R. Woeste, Neal Bhutiani, Anne E. Geller
Publikováno v:
Annals of Surgical Oncology. 27:993-1001
Women who undergo mastectomy for breast cancer may be prone to prolonged opioid use (POU). However, risk factors for long-term opioid use after mastectomy remain unclear. This study seeks to identify risk factors for POU after mastectomy. A single-in
Autor:
Chuanlin Ding, Rejeena Shrestha, Xiaojuan Zhu, Anne E. Geller, Shouzhen Wu, Matthew R. Woeste, Wenqian Li, Haomin Wang, Fang Yuan, Raobo Xu, Julia H. Chariker, Xiaoling Hu, Hong Li, David Tieri, Huang-Ge Zhang, Eric C. Rouchka, Robert Mitchell, Leah J. Siskind, Xiang Zhang, Xiaoji G. Xu, Kelly M. McMasters, Yan Yu, Jun Yan
Publikováno v:
Nature immunology.
Metastasis is the leading cause of cancer-related deaths and myeloid cells are critical in the metastatic microenvironment. Here, we explore the implications of reprogramming pre-metastatic niche myeloid cells by inducing trained immunity with whole
Autor:
Eun Jung Kim, Becca V. Baby, Ronald C. Bruntz, Matthew S. Gentry, Lindsey R. Conroy, Mariana Barbosa de Souza Rizzo, Kelly M. McMasters, Jordan T. Noe, Anne E. Geller, Hayley C. Affronti, Beatriz E. Rendon, Lance A. Johnson, Ramon C. Sun, Brian F. Clem, Robert A. Mitchell, Kathryn E. Wellen, Samantha M. Morrissey, Lyndsay E.A. Young, Ashley Wise-Mitchell, Jun Yan, Eric R. Relich
Publikováno v:
Science Advances
Description
Macrophages use mitochondrial lactate metabolism for ACLY-dependent histone acetylation, immune suppression, and tumor progression.
Lactate accumulation is a hallmark of solid cancers and is linked to the immune suppressive phen
Macrophages use mitochondrial lactate metabolism for ACLY-dependent histone acetylation, immune suppression, and tumor progression.
Lactate accumulation is a hallmark of solid cancers and is linked to the immune suppressive phen
Autor:
Zachary C Martin, Shirish Barve, David Tieri, Maiying Kong, Elizabeth A Cooke, Huang-Ge Zhang, Silvia M. Uriarte, Xiaoling Hu, Rodrigo Cavallazzi, Christopher K. Klaes, Oscar Chen, Kenneth R. McLeish, Lu Cai, James Ming Chen, Smita Ghare, Corey T. Watson, Sarah E Bush, Chuanlin Ding, Jiapeng Huang, Eric C. Rouchka, Sean P. Clifford, Jun Yan, Matthew R. Woeste, Samantha M. Morrissey, Anne E. Geller
Publikováno v:
JCI Insight, Vol 6, Iss 9 (2021)
JCI Insight
JCI Insight
SARS coronavirus 2 (SARS-CoV-2) is a novel viral pathogen that causes a clinical disease called coronavirus disease 2019 (COVID-19). Although most COVID-19 cases are asymptomatic or involve mild upper respiratory tract symptoms, a significant number