Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Anne E, Jedlicka"'
Autor:
Victoria A. Balta, Deborah Stiffler, Abeer Sayeed, Abhai K. Tripathi, Rubayet Elahi, Godfree Mlambo, Rahul P. Bakshi, Amanda G. Dziedzic, Anne E. Jedlicka, Elizabeth Nenortas, Keyla Romero-Rodriguez, Matthew A. Canonizado, Alexis Mann, Andrew Owen, David J. Sullivan, Sean T. Prigge, Photini Sinnis, Theresa A. Shapiro
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-9 (2023)
Abstract Long-acting injectable medications, such as atovaquone, offer the prospect of a “chemical vaccine” for malaria, combining drug efficacy with vaccine durability. However, selection and transmission of drug-resistant parasites is of concer
Externí odkaz:
https://doaj.org/article/4b2f7c80b9964c198820bdffbbda7944
Autor:
Han-Sol Park, Janna R. Shapiro, Ioannis Sitaras, Bezawit A. Woldemeskel, Caroline C. Garliss, Amanda Dziedzic, Jaiprasath Sachithanandham, Anne E. Jedlicka, Christopher A. Caputo, Kimberly E. Rousseau, Manjusha Thakar, San Suwanmanee, Pricila Hauk, Lateef Aliyu, Natalia I. Majewska, Sushmita Koley, Bela Patel, Patrick Broderick, Giselle Mosnaim, Sonya L. Heath, Emily S. Spivak, Aarthi Shenoy, Evan M. Bloch, Thomas J. Gniadek, Shmuel Shoham, Arturo Casadevall, Daniel Hanley, Andrea L. Cox, Oliver Laeyendecker, Michael J. Betenbaugh, Steven M. Cramer, Heba H. Mostafa, Andrew Pekosz, Joel N. Blankson, Sabra L. Klein, Aaron A.R. Tobian, David Sullivan, Kelly A. Gebo
Publikováno v:
JCI Insight, Vol 7, Iss 5 (2022)
Benchmarks for protective immunity from infection or severe disease after SARS-CoV-2 vaccination are still being defined. Here, we characterized virus neutralizing and ELISA antibody levels, cellular immune responses, and viral variants in 4 separate
Externí odkaz:
https://doaj.org/article/1448fb71cc4d4418b5b5b5d6f96c013c
Autor:
Patrick S. Creisher, Jun Lei, Morgan L. Sherer, Amanda Dziedzic, Anne E. Jedlicka, Harish Narasimhan, Anna Chudnovets, Ariana D. Campbell, Anguo Liu, Andrew Pekosz, Irina Burd, Sabra L. Klein
Publikováno v:
Frontiers in Virology, Vol 2 (2022)
Zika virus (ZIKV) infection during pregnancy causes serious adverse outcomes to the developing fetus, including fetal loss and birth defects known as congenital Zika syndrome (CZS). The mechanism by which ZIKV infection causes these adverse outcomes,
Externí odkaz:
https://doaj.org/article/1f978747f788452cb9e38df1c63b0626
Autor:
Santosh Dhakal, Camilo A. Ruiz-Bedoya, Ruifeng Zhou, Patrick S. Creisher, Jason S. Villano, Kirsten Littlefield, Jennie Ruelas Castillo, Paula Marinho, Anne E. Jedlicka, Alvaro A. Ordonez, Melissa Bahr, Natalia Majewska, Michael J. Betenbaugh, Kelly Flavahan, Alice R. L. Mueller, Monika M. Looney, Darla Quijada, Filipa Mota, Sarah E. Beck, Jacqueline Brockhurst, Alicia M. Braxton, Natalie Castell, Mitchel Stover, Franco R. D’Alessio, Kelly A. Metcalf Pate, Petros C. Karakousis, Joseph L. Mankowski, Andrew Pekosz, Sanjay K. Jain, Sabra L. Klein
Publikováno v:
mBio, Vol 12, Iss 4 (2021)
ABSTRACT In the coronavirus disease 2019 (COVID-19) pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), more severe outcomes are reported in males than in females, including hospitalizations and deaths. Animal models
Externí odkaz:
https://doaj.org/article/c26a3303ffd040088f12495ee7b31392
Autor:
Amde Selassie Shifera, Christopher Pockrandt, Natalia Rincon, Yuchen Ge, Jennifer Lu, Steven L. Salzberg, Charles Eberhart, Jennifer E. Thorne, Ales Varabyou, Anne E. Jedlicka, Karen Sun, Alan L. Scott
Publikováno v:
F1000Research, Vol 10 (2021)
Background: Metagenomic sequencing has the potential to identify a wide range of pathogens in human tissue samples. Sarcoidosis is a complex disorder whose etiology remains unknown and for which a variety of infectious causes have been hypothesized.
Externí odkaz:
https://doaj.org/article/2007947481804759b89e87f38c8b1796
Autor:
Russell P Swift, Krithika Rajaram, Cyrianne Keutcha, Hans B Liu, Bobby Kwan, Amanda Dziedzic, Anne E Jedlicka, Sean T Prigge
Publikováno v:
eLife, Vol 9 (2020)
The apicoplast of Plasmodium falciparum parasites is believed to rely on the import of three-carbon phosphate compounds for use in organelle anabolic pathways, in addition to the generation of energy and reducing power within the organelle. We genera
Externí odkaz:
https://doaj.org/article/8ba230931280402babefe27f33d8cdda
Autor:
Russell P Swift, Krithika Rajaram, Hans B Liu, Amanda Dziedzic, Anne E Jedlicka, Aleah D Roberts, Krista A Matthews, Hugo Jhun, Namandje N Bumpus, Shivendra G Tewari, Anders Wallqvist, Sean T Prigge
Publikováno v:
PLoS Pathogens, Vol 16, Iss 2, p e1008316 (2020)
Malaria parasites rely on a plastid organelle for survival during the blood stages of infection. However, the entire organelle is dispensable as long as the isoprenoid precursor, isopentenyl pyrophosphate (IPP), is supplemented in the culture medium.
Externí odkaz:
https://doaj.org/article/ae89fcfe1c5546e892dac3f249d96b6d
Autor:
Hye-Youn Cho, Anne E. Jedlicka, Frederick H. Chang, Jacqui Marzec, Alison K. Bauer, Steven R. Kleeberger
Publikováno v:
Antioxidants, Vol 10, Iss 9, p 1489 (2021)
Ozone (O3) is the predominant oxidant air pollutant associated with airway inflammation, lung dysfunction, and the worsening of preexisting respiratory diseases. We previously demonstrated the injurious roles of pulmonary immune receptors, tumor necr
Externí odkaz:
https://doaj.org/article/9dc3c50c2d91438d910a53b0197ee3e3
Autor:
Darius A Paduch, Stephanie Hilz, Andrew Grimson, Peter N Schlegel, Anne E Jedlicka, William W Wright
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0216586 (2019)
Sertoli cell-only (SCO) syndrome is a severe form of human male infertility seemingly characterized by the lack all spermatogenic cells. However, tubules of some SCO testes contain small patches of active spermatogenesis and thus spermatogonial stem
Externí odkaz:
https://doaj.org/article/5c445acec69c46aa8420035924eb2e0b
Autor:
Victoria A. Balta, Deborah Stiffler, Abeer Sayeed, Abhai K. Tripathi, Rubayet Elahi, Godfree Mlambo, Rahul P. Bakshi, Amanda G. Dziedzic, Anne E. Jedlicka, Elizabeth Nenortas, Keyla Romero-Rodriguez, Matthew A. Canonizado, Alexis Mann, Andrew Owen, David J. Sullivan, Sean T. Prigge, Photini Sinnis, Theresa A. Shapiro
Publikováno v:
bioRxiv
Rising numbers of malaria cases and deaths underscore the need for new interventions. Long-acting injectable medications, such as those now in use for HIV prophylaxis, offer the prospect of a malaria “chemical vaccine”, combining the efficacy of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8adb17cfb4ac3652a40f6dd9c6651947
https://doi.org/10.1101/2023.02.07.527535
https://doi.org/10.1101/2023.02.07.527535
